Patents by Inventor Osamu Sakuma
Osamu Sakuma has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
-
Patent number: 11927923Abstract: A management apparatus in a time synchronization system includes a time variation information receiving unit configured to acquire time variation information and position information of a time synchronization apparatus, a position information classifying unit configured to classify time synchronization apparatuses into predetermined categories based on the acquired position information, a time variation analysis configured to determine majority based on whether patterns of time variation of the time synchronization apparatuses belonging to an identical category are identical to each other, and to analyze the time variation based on the determined results, and a filtering and delivery unit configured to output an instruction to block the time information received from the positioning satellite, to the time synchronization apparatus having abnormal time variation.Type: GrantFiled: March 5, 2019Date of Patent: March 12, 2024Assignee: Nippon Telegraph and Telephone CorporationInventors: Takaaki Hisashima, Hiroki Sakuma, Kaoru Arai, Ryuta Sugiyama, Shunichi Tsuboi, Osamu Kurokawa, Kazuyuki Matsumura
-
Publication number: 20100152261Abstract: A nitrogen-containing heterocyclic derivative represented by the following general formula (I), or a hydrate or solvate thereof, which has a selective antagonistic action on the muscarinic M3 receptor and causes reduced cardiac side effect and thus is safe, and has superior pharmacological efficacy and prolonged action even by inhalation administration, and a pharmaceutical composition comprising the compound and a pharmaceutically acceptable carrier.Type: ApplicationFiled: July 25, 2006Publication date: June 17, 2010Applicant: MITSUBISHI TANABE PHARMA CORPORATIONInventors: Hideyuki Aizawa, Makoto Seki, Jun-ichi Endoh, Minoru Tanaka, Naoto Fujie, Osamu Sakuma, Takao Kamahori
-
Patent number: 5245034Abstract: Novel quinoline sulfonamino derivatives having a vessel smooth muscle relaxation activity as well as a platelet agglutination inhibitory activity and inhibitory activity to protein kinase A, myosin light chain kinase, proteinkinase C, and calmodulindependent proteinkinase II, but having little action or cardio function; a process for the production of the derivatives, and a pharmaceutical composition containing the derivative.Type: GrantFiled: March 23, 1992Date of Patent: September 14, 1993Assignee: Kiroyoshi HidakaInventors: Hiroyoshi Hidaka, Tomohiko Ishikawa, Masatoshi Hagiwara, Tsutomu Inoue, Kenji Naitoh, Osamu Sakuma, Masayuki Yuasa, Tadashi Morita, Tadashi Toshioka, Isao Umezawa, Takashi Inaba
-
Patent number: 5216150Abstract: Novel quinoline sulfonamino derivatives having a vessel smooth muscle relaxation activity as well as a platelet agglutination inhibitory activity and inhibitory activity to protein kinase A, myosin light chain kinase, proteinkinase C, and calmodulindependent proteinkinase II, but having little action or cardio function; a process for the production of the derivatives, and a pharmaceutical composition containing the derivative.Type: GrantFiled: September 12, 1991Date of Patent: June 1, 1993Assignees: Hiroyoshi Hidaka, Tobishi Yakuhin Kogyo Kabushiki KaishaInventors: Hiroyoshi Hidaka, Tomohiko Ishikawa, Masatoshi Hagiwara, Tsutomu Inoue, Kenji Naitoh, Osamu Sakuma, Masayuki Yuasa, Tadashi Morita, Tadashi Toshioka, Isao Umezawa, Takashi Inaba
-
Patent number: 5093370Abstract: A quaternary ammonium having a muscle relaxation activity compound represented by the formula (I): ##STR1## wherein R.sub.1 represents a methylene, a lower alkylenoxy, a lower alkenylene, a lower alkynylene, --CO--, --COO--, a lower alkylene carbonyloxy, --CH(OR.sub.5)--, a lower alkylenecarbonyl, a hydroxy lower alkylene, --O--, --S--, --SO--, or --SO.sub.2 --; R.sub.2 represents a hydrogen atom, a hydroxy lower alkyl, an aldehyde, a lower alkyl carbonyl, --NO.sub.2, or --NHR.sub.6 ; R.sub.3 represents a hydrogen atom of a group --R.sub.1 --(CH.sub.2).sub.a --[CH(CH.sub.2 A)--CH.sub.2 ].sub.b --A; R.sub.4 represents an anion; R.sub.5 and R.sub.6 represent a hydrogen atom or a acetyl; A represents a quaternary ammonium group; a represents an integer of 1 to 8; b represents 0 or 1; m represents an integer of 1 to 4; and (Z) represents a trivalent benzene ring, a trivalent naphthalene ring, a trivalent diphenyl or a trivalent ethane radical.Type: GrantFiled: April 9, 1990Date of Patent: March 3, 1992Assignee: Tobishi Yakuhin Kogyo Kabushiki KaishaInventors: Masayasu Kimura, Kenji Naito, Osamu Sakuma, Tadashi Morita
-
Patent number: 5081246Abstract: Novel quinoline sulfonamino derivatives having a vessel smooth muscle relaxation activity as well as a platelet agglutination inhibitory activity and inhibitory activity to protein kinase A, myosin light chain kinase, proteinkinase C, and calmodulindependent proteinkinase II, but having little action or cardio function; a process for the production of the derivatives, and a pharmaceutical composition containing the derivative.Type: GrantFiled: December 20, 1989Date of Patent: January 14, 1992Assignees: Hiroyoshi Hidaka, Tobishi Yakuhin Kogyo Kabushiki KaishaInventors: Horoyoshi Hidaka, Tomohiko Ishikawa, Masatoshi Hagiwara, Tsutomu Inoue, Kenji Naitoh, Osamu Sakuma, Masayuki Yuasa, Tadashi Morita, Tadashi Toshioka, Isao Umezawa, Takashi Inaba
-
Patent number: 5059692Abstract: Novel compounds represented by the formula: ##STR1## wherein R.sub.1 represents an alkyl group having 1 to 3 carbon atoms, R.sub.2 represents an amino group or a group of formula ##STR2## in which R.sub.4 represents an alkyl group having 1 to 3 carbon atoms, R.sub.5 represents an alkyl group having 1 to 3 carbon atoms or may combine with R.sub.6 to form a five or six membered ring containing 4 to 5 carbon atoms, R.sub.6 represents a hydrogen atom or may combine with R.sub.5 to form a five or six membered ring containing 4 to 5 carbon atoms, R.sub.3 represents a hydrogen atom, an alkyl group having 1 to 3 carbon atoms or a halogen atom, X represents a carbonyl group or a methylene group, Y represents a sulfur atom or a vinylene group and pharmaceutically acceptable salts thereof which exhibit a vasodilating activity and inhibitory activity for platelet aggregation. Thus, they are useful as therapeutic agents for treatment of angina pectoris, hypertension, throbosis and the like.Type: GrantFiled: August 30, 1990Date of Patent: October 22, 1991Inventors: Hiroyoshi Hidaka, Tomohiko Ishikawa, Tsutomu Inoue, Masayuki Yuasa, Takashi Inaba, Kenji Naito, Osamu Sakuma, Tadashi Morita, Shinpei Kidokoro
-
Patent number: 4535384Abstract: A semiconductor device comprising at least one heat sink joined to a plurality of IC packages mounted on a mother board. Plural individual heat sinks are joined to respectively corresponding IC packages each comprising a central shaft joined to and extending in substantially perpendicular relationship from a respective said package and plural, parallel spaced fins extending outwardly from and in perpendicular relationship to the shaft.Type: GrantFiled: June 12, 1984Date of Patent: August 13, 1985Assignee: Fujitsu Ltd.Inventors: Tetsushi Wakabayashi, Norio Honda, Osamu Sakuma
-
Patent number: 4435772Abstract: An interactive graphic system is provided which introduces drawing data step by step in the form of interaction to describe figures, characters, numerical figures or the like with the aid of a microcomputer. The interactive graphic system consists of a keyboard for introducing drawing data, a plotter for recording the figures, a microcomputer, and a memory unit that are constructed as a unitary structure which features small size, reduced cost and enhanced operational performance. Further, the interactive graphic system is so constructed that application software packages can be freely exchanged to diversify the functions.Type: GrantFiled: June 15, 1981Date of Patent: March 6, 1984Assignee: Yokogawa Hokushin Electric Corp.Inventors: Yoshihiro Suzuki, Shuichi Nakagawa, Nobuhisa Kawamura, Shuichi Kurihara, Osamu Sakuma, Masahiro Ito
-
Patent number: D597864Type: GrantFiled: October 16, 2008Date of Patent: August 11, 2009Assignee: Yokogawa Electric CorporationInventors: Osamu Sakuma, Noriaki Semba