Patents by Inventor Osamu Watanabe

Osamu Watanabe has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10934351
    Abstract: An objective of the present invention is to obtain two types of substantively homogeneous cancer stem cell populations which can be characterized using the cell surface marker Lgr5, and to provide cancer therapeutics using an antibody against a cell membrane molecule specifically expressed in these cancer stem cells by identifying said cell membrane molecule. A further objective is to provide, using an antibody against a cell membrane molecule specifically expressed in cancer stem cells, a reagent for detecting cancer stem cells, and a method for diagnosing and sorting cancer patients. The present inventors discovered that highly pure large intestine cancer stem cells (CSC) can be obtained in a large quantity, and identified the two types of conditions of large intestine CSCs distinguishable through Lgr5 expression. Moreover, the present inventors discovered that an antibody against a cell membrane molecule specifically expressed in said cancer stem cells can damage said cells.
    Type: Grant
    Filed: February 12, 2016
    Date of Patent: March 2, 2021
    Assignee: CHUGAI SEIYAKU KABUSHIKI KAISHA
    Inventors: Tatsumi Yamazaki, Hisafumi Okabe, Shinta Kobayashi, Takeshi Watanabe, Koichi Matsubara, Osamu Natori, Atsuhiko Kato, Masami Suzuki
  • Patent number: 10912176
    Abstract: A vehicle lamp has a roof unit. The roof unit includes a plurality of types of light output units having different illumination functions, a light emission drive unit configured to cause the plurality of types of light output units to output lights, and a monitoring sensor. The roof unit is arranged at a roof part of a vehicle.
    Type: Grant
    Filed: June 7, 2019
    Date of Patent: February 2, 2021
    Assignee: KOITO MANUFACTURING CO., LTD.
    Inventors: Takeshi Masuda, Shigeyuki Watanabe, Hajime Takeda, Akihito Horikawa, Masaaki Nakabayashi, Yusuke Nakada, Osamu Endo
  • Publication number: 20210005570
    Abstract: [Problem] To bond an electronic component on a substrate via an adhesive material satisfactorily. [Solution] A bonding device 10 for thermally bonding an electronic component 100 to a substrate 110 or to another electronic component via an adhesive material 112, the bonding device being provided with: a bonding tool 40 comprising a bonding distal-end portion 42 which includes a bonding surface 44 and tapered side surfaces 46 formed in a tapering shape becoming narrower toward the bonding surface 44, the bonding surface 44 having a first suction hole 50 for suction-attaching the electronic component 100 via an individual piece of a porous sheet 130, the tapered side surfaces 46 having second suction holes 52, 54 for suction-attaching the porous sheet 130; and a bonding control unit 30 which controls the first suction hole 50 and the second suction holes 52, 54 independently from each other.
    Type: Application
    Filed: November 29, 2017
    Publication date: January 7, 2021
    Applicant: SHINKAWA LTD.
    Inventors: Osamu WATANABE, Tomonori NAKAMURA, Toru MAEDA, Satoru NAGAI, Yuichiro NOGUCHI
  • Publication number: 20210007218
    Abstract: The conductive wiring material composition includes (A) a polymer compound having a repeating unit “a” which has a structure selected from an ammonium salt, a lithium salt, a sodium salt, a potassium salt and a silver salt of any of fluorosulfonic acid, fluorosulfonimide and fluorosulfonamide and (B) metal powder, wherein the component (B) is contained with an amount exceeding 50 parts by mass based on 100 parts by mass of a solid content of the conductive wiring material composition excluding the component (B).
    Type: Application
    Filed: July 1, 2020
    Publication date: January 7, 2021
    Applicant: SHIN-ETSU CHEMICAL CO., LTD.
    Inventors: Jun HATAKEYAMA, Koji HASEGAWA, Osamu WATANABE
  • Publication number: 20200409436
    Abstract: An electronic apparatus includes: a chassis with an air outlet provided on a first side surface thereof; a cooling fan housed in the chassis; a duct lying between an air outlet of the cooling fan and the air outlet of the chassis; and an electronic component mounted on the duct.
    Type: Application
    Filed: October 2, 2019
    Publication date: December 31, 2020
    Applicant: LENOVO (SINGAPORE) PTE. LTD.
    Inventors: Ryota Watanabe, Akinori Uchino, Osamu Yamamoto, Takuroh Kamimura
  • Patent number: 10871208
    Abstract: Provided is a tensioner with which efficiency of recirculation of oil can be improved and dependency on oil supplied from an oil pump or the like can be reduced. The tensioner includes a pressure adjustment mechanism, wherein the pressure adjustment mechanism includes a cylinder portion and a piston that is disposed in the cylinder portion so as to be capable of moving in a front-rear direction and that divides an interior space into an oil storage chamber and an adjustment space, and a liquid-tight state is maintained between the cylinder portion and the piston in all positions between a position of the piston where the piston has moved closest to the oil storage chamber side and a position of the piston where the piston has moved closest to the adjustment space side.
    Type: Grant
    Filed: October 1, 2018
    Date of Patent: December 22, 2020
    Assignee: TSUBAKIMOTO CHAIN CO.
    Inventors: Osamu Yoshida, Masanori Watanabe, Yudai Takagi, Yuji Kurematsu
  • Publication number: 20200393023
    Abstract: To provide a tensioner that can keep the oil pressure in an oil pressure chamber stable and consistently generate suitable reaction force and damping force to impact loads to reduce looseness in the chain and noise. A piston is set such as to partition an inner space of a plunger into an adjustment space on the front side and the oil pressure chamber on the rear side, a piston restricting member restricting the movement of the piston toward the adjustment space. An oil relief mechanism is configured to cause the piston to move forward when oil pressure in the oil pressure chamber rises so as to discharge oil inside the oil pressure chamber to the outside. The piston restricting member has an orifice function that can control the amount of discharged oil.
    Type: Application
    Filed: May 19, 2020
    Publication date: December 17, 2020
    Applicant: TSUBAKIMOTO CHAIN CO.
    Inventors: Yuichiro Ishikawa, Osamu Yoshida, Yuji Kurematsu, Masanori Watanabe
  • Patent number: 10864366
    Abstract: The present invention provides a bio-electrode composition including: a resin containing a urethane bond in a main chain and a silsesquioxane in a side chain; and an electro-conductive material, wherein the electro-conductive material is a polymer compound having one or more repeating units selected from fluorosulfonic acid salts shown by the following general formulae (1)-1 and (1)-2, sulfonimide salts shown by the following general formula (1)-3, and sulfonamide salts shown by the following general formula (1)-4. This can form a living body contact layer for a bio-electrode that is excellent in electric conductivity and biocompatibility, light in weight, manufacturable at low cost, and free from large lowering of the electric conductivity even when it is wetted with water or dried. The present invention also provides a bio-electrode in which the living body contact layer is formed from the bio-electrode composition, and a method for manufacturing the bio-electrode.
    Type: Grant
    Filed: October 24, 2018
    Date of Patent: December 15, 2020
    Assignee: SHIN-ETSU CHEMICAL CO., LTD.
    Inventors: Jun Hatakeyama, Motoaki Iwabuchi, Osamu Watanabe, Keisuke Niida
  • Patent number: 10857944
    Abstract: A periphery monitoring apparatus includes: a detector configured to detect a roughness state of a road surface in a traveling direction of a vehicle; an acquisition unit configured to acquire a guide marker to be superimposed onto an image based on captured image data output from an imager that captures an image of a peripheral region including the traveling direction of the vehicle, the guide marker being displayed in a manner that follows a roughness state of the road surface in the traveling direction of the vehicle; and a controller configured to superimpose the guide marker onto the image in the display manner that follows the roughness state and display the image on a display device.
    Type: Grant
    Filed: May 16, 2017
    Date of Patent: December 8, 2020
    Assignee: AISIN SEIKI KABUSHIKI KAISHA
    Inventors: Takayuki Nakasho, Kazuya Watanabe, Tetsuya Maruoka, Kinji Yamamoto, Takashi Hiramaki, Takuya Hashikawa, Naotaka Kubota, Osamu Kimura, Itsuko Ohashi, Yasumasa Yamamoto
  • Publication number: 20200361538
    Abstract: The present application discloses an engine room structure of a vehicle including: a partitioning wall configured to partition a storage space in which an engine is stored from a piping space to form an intake passage for supplying air to a combustion chamber of the engine; and an intake pipe which partially forms the intake passage in the piping space, wherein the intake pipe extends along the partitioning wall, the intake pipe being integrally formed with the partitioning wall.
    Type: Application
    Filed: August 1, 2018
    Publication date: November 19, 2020
    Inventors: Satoshi HARADA, Yousuke IWASAKI, Osamu KISHI, Masaki HARADA, Motohiro ARIKI, Yuta TAKAMURA, Kuniyoshi TASHIRO, Shigeaki WATANABE, Kazuki YAMAUCHI, Yoshiyuki KASUGA
  • Patent number: 10837527
    Abstract: To provide a tensioner capable of keeping, with a simple structure, oil pressure in an oil pressure chamber stable. The tensioner includes a pressure adjusting mechanism that adjusts oil pressure in the oil pressure chamber. The pressure adjusting mechanism includes a cylinder part, a piston unit set inside the cylinder part so as to be able to approach and separate from the oil pressure chamber, and piston biasing units that bias the piston unit toward the oil pressure chamber. A liquid tight seal condition is kept between the cylinder part and the piston unit at any position between a position where the piston unit has moved closest to the oil pressure chamber and a position where the piston unit has moved closest to the adjustment space. The piston biasing units include at least two piston springs.
    Type: Grant
    Filed: July 25, 2018
    Date of Patent: November 17, 2020
    Assignee: TSUBAKIMOTO CHAIN CO.
    Inventors: Masanori Watanabe, Yudai Takagi, Osamu Yoshida, Yuji Kurematsu
  • Patent number: 10839155
    Abstract: A morpheme analysis unit sets beforehand a meaning-candidate tag and a sentimental theme tag for a morpheme required to be input as a text. A syntax analysis unit generates an index where a clause including a meaning-candidate tag and a sentimental theme tag and a type of each tag. A meaning attribute extraction unit recognizes a clause including a meaning-candidate and a type of tag with reference to the index, and then applies a meaning attribute rule, sets a meaning attribute tag for a necessary clause, and updates the index. A sentimental analysis unit also recognizes a clause including a sentimental theme tag and a clause including a meaning attribute tag with reference to the index, and then applies a sentimental analysis rule and sets a sentimental attribute tag for a necessary clause.
    Type: Grant
    Filed: September 21, 2018
    Date of Patent: November 17, 2020
    Assignee: NOMURA RESEARCH INSTITUTE, LTD.
    Inventors: Osamu Oshima, Morio Watanabe
  • Patent number: 10809262
    Abstract: The present invention provides a specific combination of colon cancer markers based on statistical knowledge, which is capable of detecting a larger number of colon cancer patients in an earlier stage while maintaining high specificity. A multiplex colon cancer marker panel comprising a combination of five colon cancer markers of Carcinoembryonic antigen-related cell adhesion molecule 5, Carbohydrate antigen 19-9, Galectin-4, APEX nuclease and Actin-related protein 2. A method for analyzing colon cancer markers using multiplex colon cancer marker panel.
    Type: Grant
    Filed: September 11, 2015
    Date of Patent: October 20, 2020
    Assignees: Shimadzu Corporation, Osaka University
    Inventors: Makoto Watanabe, Eiichi Matsuo, Naoki Kaneko, Toshiya Matsubara, Osamu Nishimura, Masaki Mori, Hideo Matsuda, Shigeto Seno, Ichiro Takemasa
  • Patent number: 10811247
    Abstract: A cleaning and drying method of a semiconductor substrate capable of suppressing collapse or breakdown of a pattern which occur at the time of drying a cleaning solution after cleaning the substrate and decomposition of a resin at a bottom of the pattern, and capable of removing the cleaning solution with good efficiency without using a specific device.
    Type: Grant
    Filed: March 28, 2018
    Date of Patent: October 20, 2020
    Assignee: SHIN-ETSU CHEMICAL CO., LTD.
    Inventors: Tsutomu Ogihara, Osamu Watanabe, Takeshi Nagata, Naoki Kobayashi, Daisuke Kori
  • Publication number: 20200325222
    Abstract: An objective of the present invention is to obtain two types of substantively homogeneous cancer stem cell populations which can be characterized using the cell surface marker Lgr5, and to provide cancer therapeutics using an antibody against a cell membrane molecule specifically expressed in these cancer stem cells by identifying said cell membrane molecule. A further objective is to provide, using an antibody against a cell membrane molecule specifically expressed in cancer stem cells, a reagent for detecting cancer stem cells, and a method for diagnosing and sorting cancer patients. The present inventors discovered that highly pure large intestine cancer stem cells (CSC) can be obtained in a large quantity, and identified the two types of conditions of large intestine CSCs distinguishable through Lgr5 expression. Moreover, the present inventors discovered that an antibody against a cell membrane molecule specifically expressed in said cancer stem cells can damage said cells.
    Type: Application
    Filed: June 26, 2020
    Publication date: October 15, 2020
    Applicant: CHUGAI SEIYAKU KABUSHIKI KAISHA
    Inventors: Tatsumi Yamazaki, Hisafumi Okabe, Shinta Kobayashi, Takeshi Watanabe, Koichi Matsubara, Osamu Natori, Atsuhiko Kato, Masami Suzuki
  • Patent number: 10801589
    Abstract: The present invention provides a chain tensioner that, while being free from an increase in its size, reduces the number of processing parts and the number of assembling steps and reduces the outflow of oil to an outside. Inside a plunger, an inner sleeve including a check valve unit provided on a side of the inner sleeve facing a pressure oil chamber and a pressure regulating unit provided on an outer periphery of the inner sleeve is arranged. The inner sleeve has a cylinder part and a movement restricting part provided on the side of the inner sleeve facing the pressure oil chamber, and the pressure regulating unit has an annular relief valve slidably fitted onto an outer surface of the cylinder part and slidably contacting on an inner surface of the plunger and a relief spring urging the relief valve to a side of the movement restricting part.
    Type: Grant
    Filed: April 24, 2018
    Date of Patent: October 13, 2020
    Assignee: TSUBAKIMOTO CHAIN CO.
    Inventors: Masanori Watanabe, Osamu Yoshida
  • Publication number: 20200321311
    Abstract: A method of mounting a die includes: preparing a die having a bump formation surface on which a plurality of bump electrodes are formed; disposing a vacuum suction tool having a suction surface above the die such that the suction surface faces toward the bump formation surface; sandwiching a porous sheet between the suction surface and the bump formation surface and suctioning the die by the vacuum suction tool; and mounting the die that has been suctioned by the vacuum suction tool in a bonding region of a substrate with an adhesive material interposed therebetween, the porous sheet having a thickness equal to or greater than the protrusion height of the bump electrodes on the bump formation surface. Stabilization and ease of maintenance of vacuum suction can thereby be improved.
    Type: Application
    Filed: May 30, 2017
    Publication date: October 8, 2020
    Applicants: SHINKAWA LTD., VALQUA, LTD.
    Inventors: Osamu WATANABE, Tomonori NAKAMURA, Yoshihito HAGIWARA, Yuji KANAI
  • Patent number: 10793070
    Abstract: A periphery monitoring apparatus having an acquisition unit that acquires a three-dimensional model image. The three-dimensional model image indicates an irregular state of a road surface. The three-dimensional model image includes image data outputted from an imaging unit that takes a peripheral image including the road surface in a traveling direction of a vehicle and includes height data that indicates heights of individual regions of the road surface represented in the peripheral image. The periphery monitoring apparatus also includes a control that superimposes an indicator of a height of the road surface based on the height data onto each region included in the acquired three-dimensional model image and displays the three-dimensional model image on a display device.
    Type: Grant
    Filed: March 23, 2017
    Date of Patent: October 6, 2020
    Assignee: AISIN SEIKI KABUSHIKI KAISHA
    Inventors: Kazuya Watanabe, Yoji Inui, Kinji Yamamoto, Takashi Hiramaki, Takuya Hashikawa, Tetsuya Maruoka, Naotaka Kubota, Osamu Kimura, Itsuko Ohashi
  • Patent number: 10797077
    Abstract: According to one embodiment, it includes a stacked body including N-number of layers (N is an integer of 2 or more) stacked on a semiconductor substrate, opening portions penetrating the stacked body in a stacking direction, columnar bodies respectively disposed in the opening portions, and a slit dividing M-number of layers (M is an integer of 1 or more and (N?2) or less) of the stacked body in a horizontal direction from above, wherein the slit is formed with lateral surfaces respectively having a spatial periodicity in a horizontal plane.
    Type: Grant
    Filed: December 3, 2019
    Date of Patent: October 6, 2020
    Assignee: Toshiba Memory Corporation
    Inventors: Genki Kawaguchi, Masanari Fujita, Hideki Inokuma, Osamu Matsuura, Takeshi Imamura, Hideo Wada, Makoto Watanabe, Hajime Kaneko, Kenichi Fujii, Takanobu Itoh
  • Publication number: 20200291548
    Abstract: A PTFE sheet in which PTFE fibers having a diameter of 1 ?m or less are spun, the PTFE sheet having a Gurley value in the range of 1 s/100 cc/in2 to 3 s/100 cc/in2 and a shrinkage factor in a direction orthogonal to a sheet winding direction of no more than 10% when heated to 300° C. The PTFE sheet makes a die adsorbable via a tool, which is for heating the die when the die is mounted on a mounting body, by being sandwiched between the die and the tool, and suppresses the adhesion, to an adsorption surface of the tool or to the die, of an adhesion member for fixing the die to the mounted body. Through this configuration, a PTFE sheet capable of stabilizing vacuum adsorption and improving maintainability and a method for mounting a die are provided.
    Type: Application
    Filed: November 28, 2018
    Publication date: September 17, 2020
    Applicants: SHINKAWA LTD., VALQUA, LTD.
    Inventors: Osamu WATANABE, Tomonori NAKAMURA, Yoshihito HAGIWARA, Yuji KANAI