Abstract: Described herein are compositions and methods for treating retinal diseases or disorders using RPE cells.

Abstract: Bioprosthetic retinal grafts (or devices) comprising stem cell derived tissues and/or cells may be used to slow the progression of retinal degenerative disease, slow the progression of retinal degenerative disease after traumatic injury, slow the progression of age related macular degeneration (AMD), prevent retinal degenerative disease, prevent retinal degenerative disease after traumatic injury, prevent AMD, restore retinal pigment epithelium (RPE), photoreceptor cells (PRCs) and retinal ganglion cells (RGCs) lost from disease, injury or genetic abnormalities, increasing RPE, PRCs and RCGs, treat RPE, PRCs and RCG defects in a subject, or for other purposes. Bioprosthetic retinal grafts may comprise a bioprosthetic carrier or scaffold suitable for implantation into the ocular space of a subject's eye, to form a bioprosthetic retinal patch.

Abstract: The technology of this disclosure pertains generally to the correction of tissue volume deficits, and more particularly to the delivery of cells and tissue to treat soft tissue defects or to add volume to soft tissue where desired.

Abstract: Described herein are compositions and methods for treating retinal diseases or disorders using RPE cells.

Abstract: Apparatus and method for measuring Internal Ocular Pressure (IOP) comprises applying a perturbing vibration into an eye over a range of frequencies. A vibrational response of the surface of the eye is measured such as by using a laser velocimeter, the vibrational response including velocity and rate of change of the phase lag. Further, geometric properties such as volume of the eye are measured such as by using a laser interferometer to measure characteristics such as the eye's axial length and cornea thickness. Use of multiple characteristics normalizes the effect of an eye's mechanical and geometric properties and thereby more accurately determines the IOP.

Abstract: Apparatus and method for measuring Internal Ocular Pressure (IOP) comprises applying a perturbing vibration into an eye over a range of frequencies. A vibrational response of the surface of the eye is measured such as by using a laser velocimeter, said response including velocity and rate of change of the phase lag. Further, geometric properties such as volume of the eye are measured such as by using as a laser interferometer to measure characteristics such as the eye's axial length and cornea thickness. Use of multiple characteristics normalize the effect of an eye's mechanical and geometric properties and thereby more accurately determine the IOP.

Abstract: Apparatus and method for measuring intraocular pressure (IOP). comprising a vibrator which transmits a vibrational energy into an eyeball through the eyelid and measures at least one of a force or phase response in the eyeball. The measurements are taken by placing the tonometer against the eyelid to induce vibration in the underlying eyeball. A force transducer coupled to the vibrator measures the response of the eyeball from which a vibrational impedance of the eye is determined. Intraocular pressure is then calculated based on the vibrational impedance. In a preferred use of the apparatus, the tonometer is calibrated against a known intraocular pressure measurement permitting the patient to take subsequent relative IOP measurements at home or otherwise outside a traditional medical setting without the need for anesthetic or fear of infection.