Abstract: A system and method for detecting gas concentrations in a target environment uses an array of sensors. Each sensor generates a respective voltammogram in response to the environment, and the voltammograms are collectively transformed into bins that each have a distribution and a height. Normalized bins are then matched with a training set to determine whether a selected gas is present. Also, an un-normalized bin is fitted with the training set to ascertain a concentration of the gas. For this operation, the training set includes normalized and un-normalized data references previously derived from empirically defined voltammograms.

Abstract: An ultrasound catheter adapted for accessing small vessels in the distal anatomy is disclosed. The ultrasound catheter comprises an elongate tubular body formed with a delivery lumen. The flexibility and dimensions of the tubular body allow access to the distal anatomy by advancement over the guidewire. An ultrasound radiating member is provided along the distal end portion of the tubular body for emitting ultrasound energy at a treatment site. A drug solution may also be delivered through the delivery lumen and out an exit port to the treatment site.

Abstract: A vascular catheter guidewire comprises a length of wire having a proximal end, a distal end, and a central portion between the ends having a first diameter range. Typically the range of first diameters is quite narrow and within the dimensions of 0.01 and 0.02 inch. Both the distal end and the proximal end of the guidewire catheter each comprise a tip of greater flexibility than the wire of the central portion of the guidewire. The distal end tip and the proximal end tip are each defined by a length of wire which is integral with the central portion of wire and each has a range of diameters that is less than the range of first diameters. Typically, the diameters of the tip portion wires are on the order of 0.006 to 0.008 inch. The proximal end tip is significantly shorter than the distal end tip. The distal end tip is typically of greater flexibility than the proximal end tip.