Abstract: The devices and methods can prevent pulmonary aspiration thereby allowing for procedures, such as an endoscopic procedure, to be performed under sedation without general anesthesia. The device may include a first end, a second end, and a length therebetween. The body may have a central lumen along the length. The device may include a first base member fixedly disposed at the first end and a second base member fixedly disposed at the second end. The device may also include an expandable assembly movable along the length of the body with respect to the first base member. The expandable assembly may be configured to move between a collapsed configuration and an expanded configuration. The expandable assembly may also be configured to expand radially with respect to the body when in the expanded configuration.

Abstract: This invention discloses an implant for regeneration of tissue with lesions, comprising a mixture with different types of cells, particularly, mesenchymal stem cells (MSC), endothelial cells, and specific functional cells according to the nature and function of the tissue, included into the biocompatible polymeric matrix, where the cells may or may not be organized in a specific way. This innovation also discloses a method to manufacture the implant. The implant of the present invention is useful for replacement or regeneration of animal and human tissues.

Abstract: A method for organ and tissue chimerization using bone marrow cellular treatment, which avoids rejection of transplanted organs and diminishes or suspends the use of immunosuppressant drugs in patients subjected to transplant procedures. The method comprises washing the organ in an electrolyte solution. A further step of washing the organ in a wash solution. The organ is then placed in a culture solution and incubated with bone marrow cells.

Abstract: The devices and methods can prevent pulmonary aspiration thereby allowing for procedures, such as an endoscopic procedure, to be performed under sedation without general anesthesia. The device may include a first end, a second end, and a length therebetween. The body may have a central lumen along the length. The device may include a first base member fixedly disposed at the first end and a second base member fixedly disposed at the second end. The device may also include an expandable assembly movable along the length of the body with respect to the first base member. The expandable assembly may be configured to move between a collapsed configuration and an expanded configuration. The expandable assembly may also be configured to expand radially with respect to the body when in the expanded configuration.

Abstract: An organ-chimerization maintenance device. The organ-chimerization device includes at least one large cannula connector that connects to at least one of an organ's vessels. The large cannula is configured to supply a chimerization solution to the organ. The organ-chimerization device also includes a an oxygenation cannula connector that facilitates oxygenation of the organ during chimerization.

Abstract: This invention relates to novel nanocompounds that are cytotoxic to tumor cells when combined with ultraviolet light, the nanocompounds comprising multilayered carbon nanotubes with anatase-phase titanium dioxide or anatase-phase titanium dioxide and folate. The invention also relates to a composition containing said nanocompounds and to a method for the treatment of cancer; comprising the administration of said composition in co-treatment with UV radiation. The invention further relates to a method for the synthesis of the nano-compounds.

Abstract: An electrode comprising a functionalized surface exposable to a fluid sample. The functionalized surface comprises at least one polymer capable of mediating a salting-out effect and at least one detection agent that binds to an analyte comprised in the fluid sample, wherein the polymer and the detection agent are distributed on the surface of the electrode such that the detection agent is present in essentially equal amounts per surface area throughout the electrode surface and the polymer is arranged around the detection agent present in an amount allowing the reduction of the ionic strength of the fluid in proximity to the detection agent, and allowing for binding an analyte comprised in the fluid sample. A method for manufacturing a functionalized surface on an electrode, an analyte detector comprising the electrode, and the use of the analyte detector for determining at least one analyte in a fluid sample are also provided.

Abstract: This invention discloses an implant for regeneration of tissue with lesions, comprising a mixture with different types of cells, particularly, mesenchymal stem cells (MSC), endothelial cells, and specific functional cells according to the nature and function of the tissue, included into the biocompatible polymeric matrix, where the cells may or may not be organized in a specific way. This innovation also discloses a method to manufacture the implant. The implant of the present invention is useful for replacement or regeneration of animal and human tissues.

Abstract: The present invention discloses a process for the manufacture of a thin-film multilayered coating used in treating biomedical substrates and a coating in multilayered thin-film form (S/TiN/Ti/TiZr) to treat biomedical substrates used in surgical implants.

Abstract: A method for organ and tissue chimerization using bone marrow cellular treatment, which avoids rejection of transplanted organs and diminishes or suspends the use of immunosuppressant drugs in patients subjected to transplant procedures. The method comprises washing the organ in an electrolyte solution. A further step of washing the organ in a wash solution. The organ is then placed in a culture solution and incubated with bone marrow cells.

Abstract: An organ-chimerization maintenance device. The organ-chimerization device includes at least one large cannula connector that connects to at least one of an organ's vessels. The large cannula is configured to supply a chimerization solution to the organ. The organ-chimerization device also includes a an oxygenation cannula connector that facilitates oxygenation of the organ during chimerization.

Abstract: This invention relates to novel nanocompounds that are cytotoxic to tumor cells when combined with ultraviolet light, the nanocompounds comprising multilayered carbon nanotubes with anatase-phase titanium dioxide or anatase-phase titanium dioxide and folate. The invention also relates to a composition containing said nanocompounds and to a method for the treatment of cancer; comprising the administration of said composition in co-treatment with UV radiation. The invention further relates to a method for the synthesis of the nano-compounds.

Abstract: The present invention relates to a briquette used for the production of rock wool and method for the production of said briquette, wherein the briquette contains a raw material comprising rock wool waste having a fiber morphology; contains a non-fibrous inorganic binder, such as sodium silicate, to bind the raw material; and an activating agent accelerating the curing process of the briquetted raw material.

Abstract: The present invention relates to a briquette used for the production of rock wool and method for the production of said briquette, wherein the briquette contains a raw material comprising rock wool waste having a fiber morphology; contains a non-fibrous inorganic binder, such as sodium silicate, to bind the raw material; and an activating agent accelerating the curing process of the briquetted raw material.

Abstract: The present invention relates to a briquette used for the production of rock wool and method for the production of said briquette, wherein the briquette contains a raw material comprising rock wool waste having a fiber morphology; contains a non-fibrous inorganic binder, such as sodium silicate, to bind the raw material; and an activating agent accelerating the curing process of the briquetted raw material.

Abstract: The present invention relates to a briquette used for the production of rock wool and method for the production of said briquette, wherein the briquette contains a raw material comprising rock wool waste having a fiber morphology; contains a non-fibrous inorganic binder, such as sodium silicate, to bind the raw material; and an activating agent accelerating the curing process of the briquetted raw material.

Abstract: The present invention discloses a process for the manufacture of a thin-film multilayered coating used in treating biomedical substrates and a coating in multilayered thin-film form (S/TiN/Ti/TiZr) to treat biomedical substrates used in surgical implants.