Patents by Inventor Oscar H. Frazier
Oscar H. Frazier has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
-
Patent number: 11173296Abstract: A medical devices and methods related thereto are disclosed. In an embodiment, the medical device including a pump configured to be inserted within an atrium of a heart, said pump comprising an inlet and an outlet. In addition, the pump includes a flexible outflow conduit coupled to the outlet and configured to carry blood. The outflow conduit includes a radially inner surface defining a throughbore, and a radially outer surface. Further, the pump comprises a driveline configured to conduct control and power signals between the pump and an external device. The driveline extends through the outflow conduit between the radially inner surface and the radially outer surface.Type: GrantFiled: February 23, 2017Date of Patent: November 16, 2021Assignee: Texas Heart InstituteInventors: Oscar H. Frazier, William E. Cohn
-
Publication number: 20190054223Abstract: A medical devices and methods related thereto are disclosed. In an embodiment, the medical device including a pump configured to be inserted within an atrium of a heart, said pump comprising an inlet and an outlet. In addition, the pump includes a flexible outflow conduit coupled to the outlet and configured to carry blood. The outflow conduit includes a radially inner surface defining a throughbore, and a radially outer surface. Further, the pump comprises a driveline configured to conduct control and power signals between the pump and an external device. The driveline extends through the outflow conduit between the radially inner surface and the radially outer surface.Type: ApplicationFiled: February 23, 2017Publication date: February 21, 2019Inventors: Oscar H. FRAZIER, William E. COHN
-
Patent number: 9504774Abstract: A medical device comprises a pump adapted to fit within an atrium of a heart, said pump comprising an inlet and an outlet. The device further comprises a flexible outflow conduit coupled to said outlet. A method of assisting ventricular function of a heart of a patient comprises: a) inserting a continuous flow pump having an inlet and an outlet into the heart via a subclavian or jugular vein; b) attaching the outlet of the continuous flow pump to an atrial septum, wherein the inlet of the continuous flow pump is directed into a heart atrium; c) attaching the distal end of the outflow conduit to an artery; and d) operating the pump at a volumetric rate ranging from about 2 L/min to about 3 L/min.Type: GrantFiled: October 1, 2008Date of Patent: November 29, 2016Assignee: MINVASC DEVICES, LLCInventors: Oscar H. Frazier, William E. Cohn
-
Publication number: 20160166747Abstract: A medical devices and methods related thereto are disclosed. In an embodiment, the medical device including a pump configured to be inserted within an atrium of a heart, said pump comprising an inlet and an outlet. In addition, the pump includes a flexible outflow conduit coupled to the outlet. The outflow conduit includes a radially inner surface defining a throughbore, and a radially outer surface. Further, the pump comprises a driveline configured to conduct control and power signals between the pump and an external device. The driveline extends through the outflow conduit between the radially inner surface and the radially outer surface.Type: ApplicationFiled: February 24, 2016Publication date: June 16, 2016Inventors: Oscar H. Frazier, William E. Cohn
-
Patent number: 8870951Abstract: The present invention is TAH system for auto-regulating blood flow and maintaining the asymmetric pressure balance in the mammalian cardiovascular system by decreasing the resistance in blood flow and minimizing the pressure gradients to exploit the in-flow pressure sensitivities of continuous flow pumps. The system further includes laminar flow generating manifolds connected to the atrium at one end and attached to pumps linked to the great vessels at the other, such that the in-let flow sensitivities of the pumps are maximized to auto-regulate blood flow, providing adequate pulmonary and systemic arterial flow to support normal metabolism and end-organ function and maintain the appropriate asymmetric physiologic pressure balance between the systemic and pulmonary systems of the mammalian cardiovascular system.Type: GrantFiled: May 9, 2012Date of Patent: October 28, 2014Assignee: Newheart Medical Devices LLCInventors: Oscar H. Frazier, William E. Cohn
-
Patent number: 8790399Abstract: The present invention provides a total artificial heart system for auto-regulating flow and pressure balance. In one embodiment the system comprises an atrial reservoir comprising inlets and outlets connectable to a mammalian cardiovascular system and at least first and second continuous pumps connected to the atrial reservoir. In further embodiments, the system comprises an atrial reservoir comprising at least two atrial chambers, and a means for transmitting fluid pressure between the atrial chambers. The means for transmitting fluid pressure include, but are not limited to a diaphragm, an interatrial window, a flexible membrane, a valve, a filter, or combinations thereof. In another embodiment, the means for transmitting fluid pressure comprises an implantable diaphragm comprising an outer rim attachable to biological tissue and a membrane anchored at its periphery by said outer rim.Type: GrantFiled: May 27, 2010Date of Patent: July 29, 2014Assignee: Newheart Medical Devices, LLCInventors: Oscar H. Frazier, William Cohn
-
Patent number: 8226712Abstract: The present invention is TAH system for auto-regulating blood flow and maintaining the asymmetric pressure balance in the mammalian cardiovascular system by decreasing the resistance in blood flow and minimizing the pressure gradients to exploit the in-flow pressure sensitivities of continuous flow pumps. The system further includes laminar flow generating manifolds connected to the atrium at one end and attached to pumps linked to the great vessels at the other, such that the in-let flow sensitivities of the pumps are maximized to auto-regulate blood flow, providing adequate pulmonary and systemic arterial flow to support normal metabolism and end-organ function and maintain the appropriate asymmetric physiologic pressure balance between the systemic and pulmonary systems of the mammalian cardiovascular system.Type: GrantFiled: June 15, 2009Date of Patent: July 24, 2012Assignee: Newheart Medical Devices LLCInventors: Oscar H. Frazier, William E. Cohn
-
Publication number: 20110098807Abstract: The present invention provides a total artificial heart system for auto-regulating flow and pressure balance. In one embodiment the system comprises an atrial reservoir comprising inlets and outlets connectable to a mammalian cardiovascular system and at least first and second continuous pumps connected to the atrial reservoir. In further embodiments, the system comprises an atrial reservoir comprising at least two atrial chambers, and a means for transmitting fluid pressure between the atrial chambers. The means for transmitting fluid pressure include, but are not limited to a diaphragm, an interatrial window, a flexible membrane, a valve, a filter, or combinations thereof. In another embodiment, the means for transmitting fluid pressure comprises an implantable diaphragm comprising an outer rim attachable to biological tissue and a membrane anchored at its periphery by said outer rim.Type: ApplicationFiled: May 27, 2010Publication date: April 28, 2011Inventors: Oscar H. Frazier, William Cohn
-
Publication number: 20090088597Abstract: A medical device comprises a pump adapted to fit within an atrium of a heart, said pump comprising an inlet and an outlet. The device further comprises a flexible outflow conduit coupled to said outlet. A method of assisting ventricular function of a heart of a patient comprises: a) inserting a continuous flow pump having an inlet and an outlet into the heart via a subclavian or jugular vein; b) attaching the outlet of the continuous flow pump to an atrial septum, wherein the inlet of the continuous flow pump is directed into a heart atrium; c) attaching the distal end of the outflow conduit to an artery; and d) operating the pump at a volumetric rate ranging from about 2 L/min to about 3 L/min.Type: ApplicationFiled: October 1, 2008Publication date: April 2, 2009Applicant: ALPHA DEV LLCInventors: Oscar H. Frazier, William E. Cohn