Patents by Inventor Oscar MIGUEL

Oscar MIGUEL has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240119247
    Abstract: Methods for manufacturing a magnetic stripe on a card element of a card-like data carrier. involve applying at least a portion of a magnetic stripe material layer onto a card element surface of the card element using different techniques. The application of the portion of the magnetic stripe material layer onto the card element surface generates a magnetic stripe on the card element surface such that the magnetic stripe has a stripe length that is less than a length of the card element surface and has a stripe width that is less than a width of the card element surface.
    Type: Application
    Filed: October 25, 2023
    Publication date: April 11, 2024
    Inventors: Oscar Miguel FERNANDEZ LOPEZ, Thomas TARANTINO
  • Publication number: 20230416263
    Abstract: Provided herein are compounds of Formula (I): and pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof, wherein X, R1, R1a, R2a, R2b, R2c, R2d, are as defined herein, and Ring HET is a 6-membered monocyclic heteroaryl ring system of Formula: wherein L2, R13, G8, G10, G11, and G12 are as defined herein. Compounds of the present invention are useful for inhibiting CARM1 activity. Methods of using the compounds for treating CARM1-mediated disorders are also described.
    Type: Application
    Filed: November 23, 2022
    Publication date: December 28, 2023
    Applicant: Epizyme, Inc.
    Inventors: Richard Chesworth, Oscar Miguel Moradei, Gideon Shapiro, Lei Jin, Robert E. Babine
  • Patent number: 11834455
    Abstract: Provided herein are compounds of Formula (I): and pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof; wherein X, R1, R1a, R2a, R2b, R2c, R2d, are as defined herein, and Ring HET is a 6-membered monocyclic heteroaryl ring system of Formula: wherein L2, R13, G8, G10, G11, and G12 are as defined herein. Compounds of the present invention are useful for inhibiting CARM1 activity. Methods of using the compounds for treating CARM1-mediated disorders are also described.
    Type: Grant
    Filed: March 18, 2020
    Date of Patent: December 5, 2023
    Assignee: Epizyme, Inc.
    Inventors: Richard Chesworth, Oscar Miguel Moradei, Gideon Shapiro, Lei Jin, Robert E. Babine
  • Publication number: 20230279020
    Abstract: Provided herein are compounds of Formula (I): and pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof, wherein X, R1, R1a, R2a, R2b, R2c, R2d, are as defined herein, and Ring HET is a 6-membered monocyclic heteroaryl ring system of Formula: wherein L2, R13, G8, G10, G11, and G12 are as defined herein. Compounds of the present invention are useful for inhibiting CARM1 activity. Methods of using the compounds for treating CARM1-mediated disorders are also described.
    Type: Application
    Filed: March 18, 2020
    Publication date: September 7, 2023
    Applicant: Epizyme, Inc.
    Inventors: Richard Chesworth, Oscar Miguel Moradei, Gideon Shapiro, Lei Jin, Robert E. Babine
  • Patent number: 11673145
    Abstract: Method and apparatus for transforming organic and inorganic solid urban waste into aggregates, comprising an extruding machine connected to a reactor. The extruding machine is formed by an extrusion cylinder through which a piston circulates inside an extrusion cavity, which comprises three sections and is fed with a parget obtained after pre-processing the waste. The end of the third section is connected to the reactor through an opening. The reactors longitudinal shaft is formed by a rotatory steel shaft in which some steel blades are arranged, whose ends play the roles of cutting, hammering, punching and hydraulic helix as they rotate. Between the end of the blades and the wall of the reactor, there is a clearance of more than 0.1 mm of thickness. The reactor has a discharge valve to discharge the parget present in the boundary area through some openings, once it has been processed by a series of pressure, vibration energy and decompression cycles.
    Type: Grant
    Filed: January 26, 2021
    Date of Patent: June 13, 2023
    Assignee: IBIRCOM S.A.
    Inventors: Inaki Jose Garin Rotondaro, Oscar Miguel Gnadinger
  • Publication number: 20210155631
    Abstract: Provided herein are compounds of Formula (I): and pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof, wherein X, R1, R1a, R2a, R2b, R2c, R2d, are as defined herein, and Ring HET is a 6-membered monocyclic heteroaryl ring system of Formula: wherein L2, R13, G8, G10, G11, and G12 are as defined herein. Compounds of the present invention are useful for inhibiting CARM1 activity. Methods of using the compounds for treating CARM1-mediated disorders are also described.
    Type: Application
    Filed: March 18, 2020
    Publication date: May 27, 2021
    Inventors: Richard Chesworth, Oscar Miguel Moradei, Gideon Shapiro, Lei Jin, Robert E. Babine
  • Publication number: 20210146372
    Abstract: Method and apparatus for transforming organic and inorganic solid urban waste into aggregates, comprising an extruding machine connected to a reactor. The extruding machine is formed by an extrusion cylinder through which a piston circulates inside an extrusion cavity, which comprises three sections and is fed with a parget obtained after pre-processing the waste. The end of the third section is connected to the reactor through an opening. The reactors longitudinal shaft is formed by a rotatory steel shaft in which some steel blades are arranged, whose ends play the roles of cutting, hammering, punching and hydraulic helix as they rotate. Between the end of the blades and the wall of the reactor, there is a clearance of more than 0.1 mm of thickness. The reactor has a discharge valve to discharge the parget present in the boundary area through some openings, once it has been processed by a series of pressure, vibration energy and decompression cycles.
    Type: Application
    Filed: January 26, 2021
    Publication date: May 20, 2021
    Inventors: Inaki Jose GARIN ROTONDARO, Oscar Miguel GNADINGER
  • Patent number: 10933425
    Abstract: Method and apparatus (100) for transforming organic and inorganic solid urban waste into aggregates, comprising an extruding machine connected to a reactor. The extruding machine is formed by an extrusion cylinder (103) through which a piston circulates (104) inside an extrusion cavity (106), which comprises three sections (107, 110, 111) and is fed with a parget obtained after pre-processing the waste. The end (115) of the third section (111) is connected to the reactor (112) through an opening (114). The reactor's longitudinal shaft is formed by a rotatory steel shaft (116) in which some steel blades are arranged (108), whose ends play the roles of cutting, hammering, punching and hydraulic helix as they rotate. Between the end of the blades and the wall of the reactor, there is a clearance of more than 0.1 mm of thickness.
    Type: Grant
    Filed: July 17, 2015
    Date of Patent: March 2, 2021
    Assignee: IBIRCOM S.A.
    Inventors: Inaki Jose Garin Rotondaro, Oscar Miguel Gnadinger
  • Publication number: 20210043939
    Abstract: It is provided a lithium metal anode coated with a protective monolayer disposed on at least a portion of the lithium metal anode, the protective monolayer consisting of a polymer; at least one inorganic particle selected from the group consisting of Al2O3, MnO, MnO2, SiO2, TiO2, ZnO, ZrO2, Fe2O3, CuO, a silicate, an aluminosilicate, a borosilicate, and an oxysalt, or any one of the mentioned inorganic particles which are functionalized; wherein the protective monolayer has a thickness from 0.01 to 10 ?m, the inorganic particles have an average diameter from 1 to 500 nm, and the at least one inorganic particle is in an amount of 0.01 to 30 wt % related to the amount of polymer. It is also provided a method for the preparation of the protected anode, as well as a lithium metal battery comprising it.
    Type: Application
    Filed: February 4, 2019
    Publication date: February 11, 2021
    Applicant: REPSOL, S.A.
    Inventors: Rodrigo PARIS ESCRIBANO, Juan NICOLÁS AGUADO, Eneko AZACETA MUÑOZ, José Alberto BLAZQUEZ MARTÍN, Olatz LEONET BOUBETA, Idoia URDAMPILLETA GONZALEZ, Oscar MIGUEL CRESPO
  • Publication number: 20200176767
    Abstract: It is provided a chalcogenide polymer-carbon composite comprising from 70.0 to 99.0 mol % of a chalcogenide; from 0.5 to 20.0 mol % of carbon in the form of a carbonaceous material, and from 0.5 to 10.0 mol % of a crosslinking moiety, with respect to the total amount of chalcogenide, carbon, and crosslinking moiety, wherein the chalcogenide is in the form of chalcogenide chains bonded to the crosslinking moiety and they are forming a structure wherein the carbonaceous material is embedded. It is also provided a process for its preparation, as well as a cathode comprising the chalcogenide polymer-carbon composite, and a battery comprising the cathode.
    Type: Application
    Filed: May 2, 2018
    Publication date: June 4, 2020
    Inventors: Luisa María FRAGA TRILLO, Juan NICOLÁS AGUADO, Rodrigo PARIS ESCRIBANO, José Alberto BLAZQUEZ MARTÍN, Olatz LEONET BOUBETA, Eneko AZACETA MUÑOZ, Idoia URDAMPILLETA GONZALEZ, Oscar MIGUEL
  • Patent number: 10633389
    Abstract: Provided herein are compounds of Formula (I): and pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof, wherein X, R1, R1a, R2a, R2b, R2c, R2d, are as defined herein, and Ring HET is a 6-membered monocyclic heteroaryl ring system of Formula: wherein L2, R13, G8, G10, G11, and G12 are as defined herein. Compounds of the present invention are useful for inhibiting CARM1 activity. Methods of using the compounds for treating CARM1-mediated disorders are also described.
    Type: Grant
    Filed: October 2, 2018
    Date of Patent: April 28, 2020
    Assignee: Epizyme, Inc.
    Inventors: Richard Chesworth, Oscar Miguel Moradei, Gideon Shapiro, Lei Jin, Robert E. Babine
  • Patent number: 10545752
    Abstract: An integrated circuit including a ferroelectric random access memory (FRAM) for storing firmware, and a method of updating that firmware. The FRAM is constructed to selectively operate as a 2T2C FRAM memory in a normal operating mode, and as a 1T1C FRAM memory in an update mode. Updating of the stored firmware is performed by placing the FRAM in its update (1T1C) mode and writing the updated code into alternate rows of the 1T1C half-cells at each of a plurality of memory locations, while the other 1T1C half-cells in the other alternate rows retain the original data. Following verification of the updated contents, the original data in the other half-cells are overwritten with the verified updated data, and the operating mode is changed back to the normal (2T2C) operating mode.
    Type: Grant
    Filed: November 6, 2018
    Date of Patent: January 28, 2020
    Assignee: TEXAS INSTRUMENTS INCORPORATED
    Inventors: Ralf Brederlow, Oscar Miguel Guillen-Hernandez, Peter Wongeun Chung
  • Publication number: 20190135819
    Abstract: Provided herein are compounds of Formula (I): and pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof, wherein X, R1, R1a, R2a, R2b, R2c, R2d, are as defined herein, and Ring HET is a 6-membered monocyclic heteroaryl ring system of Formula: wherein L2, R13, G8, G10, G11, and G12 are as defined herein. Compounds of the present invention are useful for inhibiting CARM1 activity. Methods of using the compounds for treating CARM1-mediated disorders are also described.
    Type: Application
    Filed: October 2, 2018
    Publication date: May 9, 2019
    Inventors: Richard Chesworth, Oscar Miguel Moradei, Gideon Shapiro, Lei Jin, Robert E. Babine
  • Publication number: 20190087171
    Abstract: An integrated circuit including a ferroelectric random access memory (FRAM) for storing firmware, and a method of updating that firmware. The FRAM is constructed to selectively operate as a 2T2C FRAM memory in a normal operating mode, and as a 1T1C FRAM memory in an update mode. Updating of the stored firmware is performed by placing the FRAM in its update (1T1C) mode and writing the updated code into alternate rows of the 1T1C half-cells at each of a plurality of memory locations, while the other 1T1C half-cells in the other alternate rows retain the original data. Following verification of the updated contents, the original data in the other half-cells are overwritten with the verified updated data, and the operating mode is changed back to the normal (2T2C) operating mode.
    Type: Application
    Filed: November 6, 2018
    Publication date: March 21, 2019
    Inventors: Ralf Brederlow, Oscar Miguel Guillen-Hernandez, Peter Wongeun Chung
  • Publication number: 20190022064
    Abstract: Described herein are compounds of Formula (I-a) and (I-b), pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof. Compounds of the present invention are useful for inhibiting PRMT1 activity. Methods of using the compounds for treating PRMT1-mediated disorders are also described.
    Type: Application
    Filed: July 23, 2018
    Publication date: January 24, 2019
    Inventors: Lorna Helen Mitchell, Gideon Shapiro, Richard Chesworth, Paula Ann Boriack-Sjodin, Oscar Miguel Moradei, Kevin Wayne Kuntz
  • Patent number: 10120674
    Abstract: An integrated circuit including a ferroelectric random access memory (FRAM) for storing firmware, and a method of updating that firmware. The FRAM is constructed to selectively operate as a 2T2C FRAM memory in a normal operating mode, and as a 1T1C FRAM memory in an update mode. Updating of the stored firmware is performed by placing the FRAM in its update (1T1C) mode and writing the updated code into alternate rows of the 1T1C half-cells at each of a plurality of memory locations, while the other 1T1C half-cells in the other alternate rows retain the original data. Following verification of the updated contents, the original data in the other half-cells are overwritten with the verified updated data, and the operating mode is changed back to the normal (2T2C) operating mode.
    Type: Grant
    Filed: April 27, 2016
    Date of Patent: November 6, 2018
    Assignee: TEXAS INSTRUMENTS INCORPORATED
    Inventors: Ralf Brederlow, Oscar Miguel Guillen-Hernandez, Peter Wongeun Chung
  • Patent number: 10118931
    Abstract: Provided herein are compounds of Formula (I): and pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof, wherein X, R1, R1a, R2a, R2b, R2c, R2d, are as defined herein, and Ring HET is a 6-membered monocyclic heteroaryl ring system of Formula: wherein L2, R13, G8, G10, G11, and G12 are as defined herein. Compounds of the present invention are useful for inhibiting CARM1 activity. Methods of using the compounds for treating CARM1-mediated disorders are also described.
    Type: Grant
    Filed: December 8, 2017
    Date of Patent: November 6, 2018
    Assignee: Epizyme, Inc.
    Inventors: Richard Chesworth, Oscar Miguel Moradei, Gideon Shapiro, Lei Jin, Robert E. Babine
  • Publication number: 20180282343
    Abstract: Provided herein are compounds of Formula (I): and pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof; wherein X, R1, R1a, R2a, R2b, R2c, R2d, are as defined herein, and Ring HET is a 6-membered monocyclic heteroaryl ring system of Formula: wherein L2, R13, G8, G10, G11, and G12 are as defined herein. Compounds of the present invention are useful for inhibiting CARM1 activity. Methods of using the compounds for treating CARM1-mediated disorders are also described.
    Type: Application
    Filed: December 8, 2017
    Publication date: October 4, 2018
    Inventors: Richard Chesworth, Oscar Miguel Moradei, Gideon Shapiro, Lei Jin, Robert E. Babine
  • Publication number: 20180237397
    Abstract: Described herein are compounds of Formula (I), pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof. Compounds described herein are useful for inhibiting arginine methyltransferase activity. Methods of using the compounds for treating arginine methyltransferase-mediated disorders are also described. Formula (I).
    Type: Application
    Filed: August 15, 2017
    Publication date: August 23, 2018
    Inventors: Richard Chesworth, Lorna Helen Mitchell, Gideon Shapiro, Paula Ann Boriack-Sjodin, Oscar Miguel Moradei, Lei Jin, Kenneth W. Duncan
  • Patent number: 10039748
    Abstract: Described herein are compounds of Formula (I-a) and (I-b), pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof. Compounds of the present invention are useful for inhibiting PRMT1 activity. Methods of using the compounds for treating PRMT1-mediated disorders are also described.
    Type: Grant
    Filed: August 8, 2016
    Date of Patent: August 7, 2018
    Assignee: Epizyme, Inc.
    Inventors: Lorna Helen Mitchell, Gideon Shapiro, Richard Chesworth, Paula Ann Boriack-Sjodin, Oscar Miguel Moradei, Kevin Wayne Kuntz