Patents by Inventor Oska W. Rokhlin

Oska W. Rokhlin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Bispecific antibodies for retargeting anticancer cytotoxic lymphocytes
    Publication number: 20010001310
    Abstract: A bispecific antibody has binding specificity for a marker common to all prostate cells on one arm of the antibody, and binding specificity for T cell marker CD3 on the other antibody arm. The combined specificities bring together a tumor cell and a T effector cell, whose specificity is reprogrammed to kill the tumor cell. Invitro studies showed that the bispecific antibody achieves a much greater level of cytotoxicity than either individual antibody alone.
    Type: Application
    Filed: January 9, 2001
    Publication date: May 17, 2001
    Applicant: University of Iowa Research Foundation
    Inventors: George J. Weiner, Oska W. Rokhlin, Michael B. Cohen