Patents by Inventor Oskar Adolfsson

Oskar Adolfsson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ANTI-TAU ANTIBODIES AND METHODS OF USE
    Publication number: 20190112361
    Abstract: The invention provides anti-Tau antibodies and methods of using the same.
    Type: Application
    Filed: September 24, 2018
    Publication date: April 18, 2019
    Applicants: GENENTECH, INC., AC IMMUNE SA
    Inventors: Oskar Adolfsson, Gai Ayalon, Isidro Hotzel, Danielle Marie Di Cara
  • Anti-Tau antibodies and methods of use
    Patent number: 10112990
    Abstract: The invention provides anti-Tau antibodies and methods of using the same.
    Type: Grant
    Filed: June 2, 2016
    Date of Patent: October 30, 2018
    Assignees: Genentech, Inc., AC Immune SA
    Inventors: Oskar Adolfsson, Gai Ayalon, Isidro Hotzel, Danielle Marie Di Cara
  • Methods of diagnosing tau-protein-associated disease
    Patent number: 10100104
    Abstract: The present invention relates to methods and compositions for the therapeutic and diagnostic use in the treatment of diseases and disorders which are caused by or associated with neurofibrillary tangles. In particular, the invention relates to antibodies, which specifically recognize and bind to phosphorylated pathological protein tau-conformers and to methods and compositions involving said antibodies for the therapeutic and diagnostic use in the treatment of tauopathies including Alzheimer's Disease (AD).
    Type: Grant
    Filed: February 17, 2016
    Date of Patent: October 16, 2018
    Assignees: KATHOLIEKE UNIVERSITEIT LEUVEN, AC IMMUNE S.A.
    Inventors: Andrea Pfeifer, Andreas Muhs, Fred Van Leuven, Maria Pihlgren, Oskar Adolfsson
  • Methods of diagnosing diseases caused by or associated with neurofibrillary tangles by phosphospecific antibodies recognising Tau
    Patent number: 10066010
    Abstract: The present invention relates to methods and compositions for the therapeutic and diagnostic use in the treatment of diseases and disorders which are caused by or associated with neurofibrillary tangles. In particular, the invention relates to antibodies, which specifically recognize and bind to phosphorylated pathological protein tau-conformers and to methods and compositions involving said antibodies for the therapeutic and diagnostic use in the treatment of tauopathies including Alzheimer's Disease (AD).
    Type: Grant
    Filed: October 28, 2016
    Date of Patent: September 4, 2018
    Assignees: AC IMMUNE S.A., KATHOLIEKE UNIVERSITEIT LEUVEN
    Inventors: Andrea Pfeifer, Andreas Muhs, Maria Pihlgren, Oskar Adolfsson, Fred Van Leuven
  • Humanized tau antibody
    Patent number: 9657091
    Abstract: The present invention provides methods and compositions for the therapeutic and diagnostic use in the treatment of diseases and disorders which are caused by or associated with neurofibrillary tangles. In particular, the invention relates to humanized antibodies, which specifically recognize and bind to phosphorylated pathological protein tau-conformers to methods and compositions involving said antibodies for the therapeutic and diagnostic use in the treatment of tauopathies including Alzheimer's Disease (AD).
    Type: Grant
    Filed: March 15, 2013
    Date of Patent: May 23, 2017
    Assignees: AC Immune S.A., Katholieke Universiteit Leuven
    Inventors: Andrea Pfeifer, Andreas Muhs, Maria Pihlgren, Oskar Adolfsson, Fred Van Leuven
  • PHOSPHOSPECIFIC ANTIBODIES RECOGNISING TAU
    Publication number: 20170137502
    Abstract: The present invention relates to methods and compositions for the therapeutic and diagnostic use in the treatment of diseases and disorders which are caused by or associated with neurofibrillary tangles. In particular, the invention relates to antibodies, which specifically recognize and bind to phosphorylated pathological protein tau-conformers and to methods and compositions involving said antibodies for the therapeutic and diagnostic use in the treatment of tauopathies including Alzheimer's Disease (AD).
    Type: Application
    Filed: October 28, 2016
    Publication date: May 18, 2017
    Applicants: AC IMMUNE S.A., KATHOLIEKE UNIVERSITEIT LEUVEN
    Inventors: Andrea Pfeifer, Andreas Muhs, Maria Pihlgren, Oskar Adolfsson, Fred Van Leuven
  • Anti-tau antibodies and methods of use
    Patent number: 9598485
    Abstract: The present invention relates to anti-Tau antibodies, such as antibodies that bind to a phosphorylated epitope on human Tau protein with high specificity and/or affinity, and methods of using the same.
    Type: Grant
    Filed: March 12, 2014
    Date of Patent: March 21, 2017
    Assignees: AC IMMUNE S.A., GENENTECH, INC.
    Inventors: Gai Ayalon, Danielle Marie Di Cara, Isidro Hotzel, Andrea Pfeifer, Andreas Muhs, Maria Pihlgren, Oskar Adolfsson
  • Phosphospecific antibodies recognising tau
    Patent number: 9540434
    Abstract: The present invention relates to methods and compositions for the therapeutic and diagnostic use in the treatment of diseases and disorders which are caused by or associated with neurofibrillary tangles, in particular, the invention relates to antibodies, which specifically recognize and bind to phosphorylated pathological protein tau-conformers and to methods and compositions involving said antibodies for the therapeutic and diagnostic use in the treatment of tauopathies including Alzheimer's Disease (AD).
    Type: Grant
    Filed: October 5, 2012
    Date of Patent: January 10, 2017
    Assignees: AC IMMUNE S.A., KATHOLIEKE UNIVERSITEIT LEUVEN
    Inventors: Andrea Pfeifer, Andreas Muhs, Maria Pihlgren, Oskar Adolfsson, Fred Van Leuven
  • ANTI-TAU ANTIBODIES AND METHODS OF USE
    Publication number: 20160376351
    Abstract: The invention provides anti-Tau antibodies and methods of using the same.
    Type: Application
    Filed: June 2, 2016
    Publication date: December 29, 2016
    Applicants: GENENTECH, INC., AC IMMUNE SA
    Inventors: Oskar Adolfsson, Gai Ayalon, Isidro Hotzel, Danielle Marie Di Cara
  • Pharmaceutical Composition
    Publication number: 20160304590
    Abstract: The present invention relates to methods and compositions for the therapeutic and diagnostic use in the treatment of diseases and disorders which are caused by or associated with neurofibrillary tangles. In particular, the invention relates to antibodies, which specifically recognize and bind to phosphorylated pathological protein tau-conformers and to methods and compositions involving said antibodies for the therapeutic and diagnostic use in the treatment of tauopathies including Alzheimer's Disease (AD).
    Type: Application
    Filed: February 17, 2016
    Publication date: October 20, 2016
    Inventors: Andrea Pfeifer, Andreas Muhs, Fred Van Leuven, Maria Pihlgren, Oskar Adolfsson
  • Pharmaceutical composition
    Patent number: 9304138
    Abstract: The present invention relates to methods and compositions for the therapeutic and diagnostic use in the treatment of diseases and disorders which are caused by or associated with neurofibrillary tangles. In particular, the invention relates to antibodies, which specifically recognize and bind to phosphorylated pathological protein tau-conformers and to methods and compositions involving said antibodies for the therapeutic and diagnostic use in the treatment of tauopathies including Alzheimer's Disease (AD).
    Type: Grant
    Filed: October 7, 2011
    Date of Patent: April 5, 2016
    Assignees: KATHOLIEKE UNIVERSITEIT LEUVEN, AC IMMUNE S.A.
    Inventors: Andrea Pfeifer, Andreas Muhs, Fred Van Leuven, Maria Pihlgren, Oskar Adolfsson
  • ANTI-TAU ANTIBODIES AND METHODS OF USE
    Publication number: 20160024193
    Abstract: The present invention relates to anti-Tau antibodies, such as antibodies that bind to a phosphorylated epitope on human Tau protein with high specificity and/or affinity, and methods of using the same.
    Type: Application
    Filed: March 12, 2014
    Publication date: January 28, 2016
    Inventors: Gai Ayalon, Danielle Marie Di Cara, Isidro Hotzel, Andrea Pfeifer, Andreas Muhs, Maria Pihlgren, Oskar Adolfsson
  • Methods for identifying safe and functional humanized antibodies
    Patent number: 9221900
    Abstract: The present invention is related to safe and functional antibodies for the therapeutic and diagnostic use in the treatment of an amyloidosis, a group of disorders and abnormalities associated with amyloid protein, such as Alzheimer's disease.
    Type: Grant
    Filed: July 29, 2011
    Date of Patent: December 29, 2015
    Assignees: AC IMMUNE S.A., GENENTECH, INC.
    Inventors: Andrea Pfeifer, Andreas Muhs, Oskar Adolfsson, Ryan J. Watts
  • HUMANIZED TAU ANTIBODY
    Publication number: 20150175682
    Abstract: The present invention provides, methods end composites for the therapeutic and diagnostic use in the treatment of diseases and disorders which are caused by or associated with neurofibrillary tangles. In particular, the Invention relates to humanized antibodies, which specifically recognize and bind to phosphorylated pathological protein tau-conformers to methods and compositions involving antibodies for the therapeutic and diagnostic use In the treatment of tauopathies including Alzheimer's Disease (AD).
    Type: Application
    Filed: March 15, 2013
    Publication date: June 25, 2015
    Inventors: Andrea Pfeifer, Andreas Muhs, Maria Pihlgren, Oskar Adolfsson, Fred Van Leuven, Gai Ayalon, Danielle Marie Di Cara, Isidro Hotzel
  • PHOSPHOSPECIFIC ANTIBODIES RECOGNISING TAU
    Publication number: 20140294731
    Abstract: The present invention relates to methods and compositions for the therapeutic and diagnostic use in the treatment of diseases and disorders which are caused by or associated with neurofibrillary tangles, in particular, the invention relates to antibodies, which specifically recognize and bind to phosphorylated pathological protein tau-conformers and to methods and compositions involving said antibodies for the therapeutic and diagnostic use in the treatment of tauopathies including Alzheimer's Disease (AD).
    Type: Application
    Filed: October 5, 2012
    Publication date: October 2, 2014
    Inventors: Andrea Pfeifer, Andreas Muhs, Maria Pihlgren, Oskar Adolfsson, Fred Van Leuven
  • PHARMACEUTICAL COMPOSITION
    Publication number: 20120276009
    Abstract: The present invention relates to methods and compositions for the therapeutic and diagnostic use in the treatment of diseases and disorders which are caused by or associated with neurofibrillary tangles. In particular, the invention relates to antibodies, which specifically recognize and bind to phosphorylated pathological protein tau-conformers and to methods and compositions involving said antibodies for the therapeutic and diagnostic use in the treatment of tauopathies including Alzheimer's Disease (AD).
    Type: Application
    Filed: October 7, 2011
    Publication date: November 1, 2012
    Applicants: KATHOLIEKE UNIVERSITEIT LEUVEN, AC IMMUNE S.A.
    Inventors: Andrea Pfeifer, Andreas Muhs, Fred Van Leuven, Maria Pihlgren, Oskar Adolfsson
  • Safe and functional humanized antibodies
    Publication number: 20120064065
    Abstract: The present invention is related to safe and functional antibodies for the therapeutic and diagnostic use in the treatment of an amyloidosis, a group of disorders and abnormalities associated with amyloid protein, such as Alzheimer's disease.
    Type: Application
    Filed: July 29, 2011
    Publication date: March 15, 2012
    Inventors: Andrea Pfeifer, Andreas Muhs, Oskar Adolfsson, Ryan J. Watts