Patents by Inventor Oskar Koch

Oskar Koch has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11964955
    Abstract: Described are specific mixtures comprising one or more (cannabinoid) compounds of the formula (A) and/or one or more of their salts as well was methods for their production. Further described are a compound of the formula (A), a salt of the formula (A) and a corresponding mixture for use as a medicament or, respectively, for use in a method for therapeutic treatment of the human or animal body. Described are also corresponding pharmaceutical formulations, cosmetic preparations and preparations for pleasure and/or nutrition, suitable for consumption, as well as methods for producing CBDV and THCV.
    Type: Grant
    Filed: December 7, 2020
    Date of Patent: April 23, 2024
    Assignee: SYMRISE AG
    Inventors: Oskar Koch, Marcus Rudolf Götz
  • Publication number: 20240108559
    Abstract: The present invention relates to a method for synthesizing sinapoyl malate comprising the steps of (a) (i) reacting syringaldehyde with acetic acid anhydride and an alkali metal acetate; or (ii) reacting sinapinic acid with acetic acid anhydride, and (b) cleaving the anhydride of the acetyl protected reaction product of (a) by exposing to water and an aliphatic alcohol to form protected sinapinic acid, (c) esterifyinig the protected sinapinic acid by reacting with an alkyl protected carboxylic acid ester to form protected sinapoyl malate, and (d) reacting the protected sinapoyl malate with aqueous acid to yield sinapoyl malate.
    Type: Application
    Filed: December 8, 2023
    Publication date: April 4, 2024
    Inventors: Nadine PERNODET, Chia-Wen CHEN, Kelly DONG, Jingyu HUANG, Oskar KOCH, Nikolas BUGDAHN
  • Patent number: 11485700
    Abstract: The present invention relates to a method of producing a compound of formula (I) or a salt of a compound of formula (I). The invention also relates to a compound of formula (I) or a salt of a compound of formula (I) for use in a therapeutic method to achieve one or more therapeutic effects as well as for use in the treatment and/or prevention of certain diseases. Furthermore, the invention provides a pharmaceutical composition comprising one or more compound(s) of formula (I) or salt(s) of compound(s) of formula (I).
    Type: Grant
    Filed: June 28, 2018
    Date of Patent: November 1, 2022
    Assignee: SYMRISE AG
    Inventors: Bernd Fiebich, Matthias Winkler, Marcus Rudolf Götz, Oskar Koch
  • Patent number: 11123272
    Abstract: Suggested is a cosmetic blend, comprising or consisting of (a) at least one TRPV1 and/or TRPV3 modulator and (b1) at least one 1,2-alkandiol having 5 to 12 carbon atoms and/or (b2) at least one polyol having 3 to 12 carbon atoms and 3 to 6 hydroxyl groups.
    Type: Grant
    Filed: December 2, 2016
    Date of Patent: September 21, 2021
    Assignee: Symrise AG
    Inventors: Caroline Baptiste, Aurélie Trunet, Gabriele Vielhaber, Sabine Lange, Dominik Stuhlmann, Benoit Join, Oskar Koch
  • Publication number: 20210253509
    Abstract: The present invention relates to a method of producing a compound of formula (I) or a salt of a compound of formula (I). The invention also relates to a compound of formula (I) or a salt of a compound of formula (I) for use in a therapeutic method to achieve one or more therapeutic effects as well as for use in the treatment and/or prevention of certain diseases. Furthermore, the invention provides a pharmaceutical composition comprising one or more compound(s) of formula (I) or salt(s) of compound(s) of formula (I).
    Type: Application
    Filed: June 28, 2018
    Publication date: August 19, 2021
    Inventors: Bernd FIEBICH, Matthias WINKLER, Marcus Rudolf GÖTZ, Oskar KOCH
  • Publication number: 20210137805
    Abstract: A topical composition comprising a synthetic compound that is an ester of sinapinic acid, a method for treating skin to provide one or more benefits selected from (a) protecting against UV radiation, (b) inhibiting DNA damage in skin cells, (c) inhibiting skin inflammation, and (d) scavenging free radicals by topically applying a composition containing the synthetic compound and a method for synthesizing the compound.
    Type: Application
    Filed: March 6, 2018
    Publication date: May 13, 2021
    Inventors: Nadine PERNODET, Chia-Wen CHEN, Kelly DONG, Jingyu HUANG, Oskar KOCH, Nikolas BUGDAHN
  • Patent number: 10988434
    Abstract: A fragrance mixture and its applications, in particular perfume oils, cosmetic agents, application agents or washing and cleaning agents, containing a sensory effective amount of (i) (E)-2-methyl-but-2-endicarboxylic acid diethyl ester, (ii) (Z)-2-methyl-but-2-endicarboxylic acid diethyl ester or (iii) 2-methylenebutanedicarboxylic acid diethyl ester and mixtures thereof and analogous esters derived from these compounds and mixtures.
    Type: Grant
    Filed: September 27, 2017
    Date of Patent: April 27, 2021
    Assignee: SYMRISE AG
    Inventors: Vijayanand Chandrasekaran, Johannes Panten, Oskar Koch, Edison Diaz Gomez
  • Publication number: 20210107885
    Abstract: Described are specific mixtures comprising one or more (cannabinoid) compounds of the formula (A) and/or one or more of their salts as well was methods for their production. Further described are a compound of the formula (A), a salt of the formula (A) and a corresponding mixture for use as a medicament or, respectively, for use in a method for therapeutic treatment of the human or animal body. Described are also corresponding pharmaceutical formulations, cosmetic preparations and preparations for pleasure and/or nutrition, suitable for consumption, as well as methods for producing CBDV and THCV.
    Type: Application
    Filed: December 7, 2020
    Publication date: April 15, 2021
    Inventors: Oskar KOCH, Marcus Rudolf GÖTZ
  • Patent number: 10913729
    Abstract: Described are specific mixtures comprising one or more (cannabinoid) compounds of the formula (A) and/or one or more of their salts as well was methods for their production. Further described are a compound of the formula (A), a salt of the formula (A) and a corresponding mixture for use as a medicament or, respectively, for use in a method for therapeutic treatment of the human or animal body. Described are also corresponding pharmaceutical formulations, cosmetic preparations and preparations for pleasure and/or nutrition, suitable for consumption, as well as methods for producing CBDV and THCV.
    Type: Grant
    Filed: November 6, 2018
    Date of Patent: February 9, 2021
    Assignee: SYMRISE AG
    Inventors: Oskar Koch, Marcus Rudolf Götz
  • Publication number: 20200121575
    Abstract: Suggested is a cosmetic blend, comprising or consisting of (a) at least one TRPV1 and/or TRPV3 modulator and (b1) at least one 1,2-alkandiol having 5 to 12 carbon atoms and/or (b2) at least one polyol having 3 to 12 carbon atoms and 3 to 6 hydroxyl groups.
    Type: Application
    Filed: December 2, 2016
    Publication date: April 23, 2020
    Inventors: Caroline BAPTISTE, Auélie TRUNET, Gabriele VIELHABER, Sabine LANGE, Dominik STUHLMANN, Benoit JOIN, Oskar KOCH
  • Publication number: 20200010402
    Abstract: A fragrance mixture and its applications, in particular perfume oils, cosmetic agents, application agents or washing and cleaning agents, containing a sensory effective amount of (i) (E)-2-methyl-but-2-endicarboxylic acid diethyl ester, (ii) (Z)-2-methyl-but-2-endicarboxylic acid diethyl ester or (iii) 2-methylenebutanedicarboxylic acid diethyl ester and mixtures thereof and analogous esters derived from these compounds and mixtures.
    Type: Application
    Filed: September 27, 2017
    Publication date: January 9, 2020
    Inventors: Vijayanand Chandrasekaran, Johannes Panten, Oskar Koch, Edison Diaz Gomez
  • Patent number: 10442751
    Abstract: The present invention relates to a method for producing a substituted alkyl cycloalkanone, comprising the alkylation of a cycloalkanone with an alkene derivative in the presence of a metal oxide, where n is 2 to 20, m is 0 to 10, and R is a functional group.
    Type: Grant
    Filed: January 13, 2016
    Date of Patent: October 15, 2019
    Assignee: SYMRISE AG
    Inventors: Atia Hanan, Reinhard Eckelt, Angela Koeckritz, Johannes Panten, Peter Esser, Oskar Koch
  • Publication number: 20190077783
    Abstract: Described are specific mixtures comprising one or more (cannabinoid) compounds of the formula (A) and/or one or more of their salts as well was methods for their production. Further described are a compound of the formula (A), a salt of the formula (A) and a corresponding mixture for use as a medicament or, respectively, for use in a method for therapeutic treatment of the human or animal body. Described are also corresponding pharmaceutical formulations, cosmetic preparations and preparations for pleasure and/or nutrition, suitable for consumption, as well as methods for producing CBDV and THCV.
    Type: Application
    Filed: November 6, 2018
    Publication date: March 14, 2019
    Inventors: Oskar KOCH, Marcus Rudolf GÖTZ
  • Publication number: 20180244642
    Abstract: Described are specific mixtures comprising one or more (cannabinoid) compounds of the formula (A) and/or one or more of their salts as well was methods for their production. Further described are a compound of the formula (A), a salt of the formula (A) and a corresponding mixture for use as a medicament or, respectively, for use in a method for therapeutic treatment of the human or animal body. Described are also corresponding pharmaceutical formulations, cosmetic preparations and preparations for pleasure and/or nutrition, suitable for consumption, as well as methods for producing CBDV and THCV.
    Type: Application
    Filed: February 26, 2016
    Publication date: August 30, 2018
    Inventors: Oskar KOCH, Marcus Rudolf GÖTZ
  • Publication number: 20180022683
    Abstract: The present invention relates to a method for producing a substituted alkyl cycloalkanone of formula (I), having the alkylation of a cycloalkanone of formula (II) with an alkene derivative of formula (III) in the presence of a metal oxide, where n is 2 to 20, m is 0 to 10, and R is a functional group.
    Type: Application
    Filed: January 13, 2016
    Publication date: January 25, 2018
    Applicant: SYMRISE AG
    Inventors: Atia HANAN, Reinhard ECKELT, Angela KOECKRITZ, Johannes PANTEN, Peter ESSER, Oskar KOCH
  • Patent number: 9820923
    Abstract: The invention relates generally to new compounds of formula (I), wherein R1, R?1, R2, R?2, R3, R?3, R4 R?4, R5, R?5, R6, R7 are independently of one another and denote hydrogen, hydroxyl, C1 to C6-alkyl group or R6 and R7 form together a C5-C6 ring system, and wherein n=0, 1, 2, 3, or 4. Moreover, the invention relates to the use of one or more compounds of formula (I) in cosmetic or pharmaceutical compositions, which are preferably dermatological compositions and are preferably used topically.
    Type: Grant
    Filed: June 4, 2014
    Date of Patent: November 21, 2017
    Assignee: Symrise AG
    Inventors: Dominik Stuhlmann, Imke Meyer, Oskar Koch, Helko Oertling, Martina Herrmann, Claudia Gömann
  • Patent number: 9676691
    Abstract: A method is described for producing a compound having the formula (I) or an admixture comprising a compound having the formula (I), having the following steps: dissolving an indanone having the formula (II) in a solvent or in an admixture which contains a solvent, the solvent being selected from the group of solvents which form an azeotrope with water, converting the indanone having the formula (II) with an aromatic aldehyde having the formula (III) in the presence of at least one organic base, according to the drawing: where R1 and R2 independently of each other signify hydrogen or a branched or unbranched alkyl group having from 1 to 12 carbon atoms and where R3, R4, R5, R6, R7, R8, R9, R10 and R11 independently of each other signify hydrogen, hydroxy or a branched or unbranched alkyl or alkoxy group having from 1 to 12 carbon atoms and removing water formed from the reaction admixture during the conversion.
    Type: Grant
    Filed: August 24, 2012
    Date of Patent: June 13, 2017
    Assignee: SYMRISE AG
    Inventors: Oskar Koch, Dietmar Schatkowski, William Johncock, Christel Jahnke, Karl-Georg Fahlbusch
  • Patent number: 9670133
    Abstract: Specific compositions comprising one or multiple (cannabinoid) compound(s) of formula (A) and/or one or multiple salt(s) thereof are described as well as methods for their manufacture. A compound of formula (A), a salt of formula (A) and a respective composition for use as medicine and for use in a method for the therapeutic treatment of the human or animal body, respectively, are also described. Furthermore, corresponding pharmaceutical formulations, cosmetic preparations and foodstuff and/or gourmet or snack preparations fit for consumption as well as a method for the manufacture of delta-9-tetrahydrocannabinol are described.
    Type: Grant
    Filed: June 30, 2014
    Date of Patent: June 6, 2017
    Assignee: SYMRISE AG
    Inventors: Oskar Koch, Marcus Rudolf Götz, Jan Looft, Tobias Vössing
  • Publication number: 20160128923
    Abstract: The invention relates generally to new compounds of formula (I), wherein R1, R?1, R2, R?2, R3, R?3, R4 R?4, R5, R?5, R6, R7 are independently of one another and denote hydrogen, hydroxyl, C1 to C6-alkyl group or R6 and R7 form together a C5-C6 ring system, and wherein n=0, 1, 2, 3, or 4. Moreover, the invention relates to the use of one or more compounds of formula (I) in cosmetic or pharmaceutical compositions, which are preferably dermatological compositions and are preferably used topically.
    Type: Application
    Filed: June 4, 2014
    Publication date: May 12, 2016
    Inventors: Dominik STUHLMANN, Imke MEYER, Oskar KOCH, Helko OERTLING, Martina HERRMANN, Claudia GÖMANN
  • Publication number: 20160100574
    Abstract: Suggested is an antimicrobial agent comprising at least one glycerylether of formula (I) in which R1 represents a benzyl, methylbenzyl, phenlethyl, or phenylpropyl radical, or a glycerylether of formula (II) in which R2 stands for a linear or branched alkyl radical having 2 to 12 carbon atoms, on condition that in case of glycerylethers of formula (II) two or three of said species are present.
    Type: Application
    Filed: May 20, 2014
    Publication date: April 14, 2016
    Applicant: SYMRISE AG
    Inventors: Manuel Pesaro, Oskar Koch, Gerhard Schmaus, Antje Köhler, Jessica Grieger