Patents by Inventor Osker Zelder

Osker Zelder has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHOD OF REDUCING GENE EXPRESSION USING MODIFIED CODON USAGE
    Publication number: 20100041107
    Abstract: The present invention is directed to a method of reducing the amount of at least one polypeptide in a host cell by expressing a nucleotide sequence encoding for the polypeptide in the host cell wherein the nucleotide sequence uses codons that are rarely used according to the codon usage of the host organism. Furthermore, the present invention relates to nucleotide sequences encoding for a polypeptide with a codon usage that has been adjusted to use codons that are only rarely used according to the codon usage of the host organism. The present invention further relates to the use of such sequences and methods for producing fine chemicals such as amino acids, sugars, lipids, oils, carbohydrates, vitamins, cofactors etc.
    Type: Application
    Filed: October 18, 2007
    Publication date: February 18, 2010
    Applicant: BASF SE
    Inventors: Andrea Herold, Corinna Klopprogge, Hartwig Schröder, Osker Zelder, Weol Kyu Jeong