Patents by Inventor Osman A. Basaran
Osman A. Basaran has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20210389221Abstract: A method is provided for determining the surface viscosity of a liquid in which a thread is formed from a drop of the liquid. The thread is lengthened and its minimum radius h0 is determined at multiple times between the thread formation and thread pinch-off. The minimum radius and associated time values are used to determine a linear relationship of minimum radius and time, with the coefficient of the linear relationship, or the slope X of the line in the linear relationship, corresponding to the surface viscosity ?s of the liquid according to one of the following equations: x = 0 . 0 ? 7 ? 0 ? 9 1 + 5 ? B s0 / 3 ? ? h 0 , ( 1 ) where Bs0=?s/?R in which h0 is defined as above, R is the dimension of the feature on which the drop is provided and ? is the bulk viscosity of the liquid, or x = 0 .Type: ApplicationFiled: June 11, 2021Publication date: December 16, 2021Inventors: Hansol Wee, Brayden W. Wagoner, Pritish M. Kamat, Vishrut Garg, Osman A. Basaran
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Patent number: 8186790Abstract: Apparatus and methods for producing a drop from a Drop on demand (DOD) dispenser, the drop having a radius that is much smaller than the radius of the nozzle that expels the drop. Generally, the Ohnesorge number is less than about 0.1. Various embodiments of the invention are found within a four dimensional space defined in terms of the Ohnesorge number, the Weber number, the actuation frequency, and the initial conditions.Type: GrantFiled: March 16, 2009Date of Patent: May 29, 2012Assignee: Purdue Research FoundationInventors: Osman Basaran, Qi Xu
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Patent number: 7374944Abstract: Bioanalytical device that includes a biofunctional component and an optional sensor component. The device includes arrays of addressable, durable, asymmetric biofunctional membranes containing protein transducers capable of unidirectional transport of analytes. Suitable protein transducers include members of the ATP-binding cassette family, such as P-glycoprotein.Type: GrantFiled: October 3, 2002Date of Patent: May 20, 2008Assignee: Purdue Research FoundationInventors: David H. Thompson, Christine A. Hrycyna, Gil U. Lee, Osman A. Basaran, Kinam Park, Igal Szleifer
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Publication number: 20050175501Abstract: Bioanalytical device that includes a biofunctional component and an optional sensor component. The device includes arrays of addressable, durable, asymmetric biofunctional membranes containing protein transducers capable of unidirectional transport of analytes. Suitable protein transducers include members of the ATP-binding cassette family, such as P-glycoprotein.Type: ApplicationFiled: October 3, 2002Publication date: August 11, 2005Inventors: David Thompson, Christine Hrycyna, Gil Lee, Osman Basaran, Kinam Park, Igal Szleifer
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Patent number: 6599627Abstract: A solvent exchange method is employed to provide microencapsulated compositions, such as microcapsules of pharmaceutical preparations. The method is based on an exchange of water and a hydrophilic organic solvent, whereby a decline in solvent quality for the organic solvent causes a polymer dissolved therein to be deposited onto an aqueous core. Optimal results are rationalized in terms of a balance of water solubility and surface tension for the organic solvent. In a preferred embodiment, microcapsules of selected drugs are formed by contacting microdroplets of an aqueous solution containing the drug with the organic solvent containing a polymer dissolved therein. A preferred method employs biodegradable poly(lactic acid-co-glycolic acid) (PLGA) dissolved in acetic acid, ethyl acetate, methyl acetate, or ethyl formate, to form a PLGA membrane around an aqueous drug core. The method is particularly attractive for encapsulating protein-based drugs without substantial denaturation.Type: GrantFiled: December 13, 2001Date of Patent: July 29, 2003Assignee: Purdue Research FoundationInventors: Yoon Yeo, Alvin Un-Teh Chen, Osman A. Basaran, Kinam Park
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Patent number: 6513894Abstract: A method and apparatus for dispensing fluid from a drop-on-demand (DOD) fluid dispenser. The method involves withdrawing fluid in the dispenser for a first duration of time, followed by a second duration of time during which the fluid is propelled toward the orifice of the dispenser. Following the period during which the fluid is propelled, there is a second withdrawing of the fluid into the dispenser. The duration of the propelling period is shorter than the duration of either the first withdrawing or the second withdrawing. The propelling of the fluid results in the extension of a small tongue of fluid from the meniscus of the fluid. The second withdrawing of the fluid results in a retraction of the meniscus into the passageway such that only the small tongue of fluid separates and is ejected from the dispenser.Type: GrantFiled: November 20, 2000Date of Patent: February 4, 2003Assignee: Purdue Research FoundationInventors: Alvin U. Chen, Osman A. Basaran
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Publication number: 20020160109Abstract: A solvent exchange method is employed to provide microencapsulated compositions, such as microcapsules of pharmaceutical preparations. The method is based on an exchange of water and a hydrophilic organic solvent, whereby a decline in solvent quality for the organic solvent causes a polymer dissolved therein to be deposited onto an aqueous core. Optimal results are rationalized in terms of a balance of water solubility and surface tension for the organic solvent. In a preferred embodiment, microcapsules of selected drugs are formed by contacting microdroplets of an aqueous solution containing the drug with the organic solvent containing a polymer dissolved therein. A preferred method employs biodegradable poly(lactic acid-co-glycolic acid) (PLGA) dissolved in acetic acid, ethyl acetate, methyl acetate, or ethyl formate, to form a PLGA membrane around an aqueous drug core. The method is particularly attractive for encapsulating protein-based drugs without substantial denaturation.Type: ApplicationFiled: December 13, 2001Publication date: October 31, 2002Inventors: Yoon Yeo, Alvin Un-Teh Chen, Osman A. Basaran, Kinam Park
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Patent number: 5759228Abstract: A nozzle for an electric dispersion reactor includes two coaxial cylindrical bodies, the inner one of the two delivering disperse phase fluid into a continuous phase fluid. A potential difference generated by a voltage source creates a dispersing electric field at the end of the inner electrode.Type: GrantFiled: January 16, 1996Date of Patent: June 2, 1998Assignee: Martin Marietta Energy Systems, Inc.Inventors: Warren G. Sisson, Michael T. Harris, Timothy C. Scott, Osman A. Basaran
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Patent number: 5738821Abstract: A nozzle for an electric dispersion reactor includes two concentric electrodes, the inner one of the two delivering disperse phase fluid into a continuous phase fluid. A potential difference generated by a voltage source creates a dispersing electric field at the end of the inner electrode.Type: GrantFiled: September 29, 1995Date of Patent: April 14, 1998Assignee: Lockheed Martin Energy Research CorporationInventors: Warren G. Sisson, Osman A. Basaran, Michael T. Harris
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Patent number: 5603819Abstract: The present invention provides a method for preparing irreversible linear aggregates (fibrils) of metal oxide powders by utilizing static or pulsed DC electrical fields across a relatively non-conducting liquid solvent in which organometal compounds or silicon alkoxides have been dissolved. The electric field is applied to the relatively non-conducting solution throughout the particle formation and growth process promoting the formation of either linear aggregates (fibrils) or spherical shaped particles as desired. Thus the present invention provides a physical method for altering the size, shape and porosity of precursor hydrous metal oxide or hydrous silicon oxide powders for the development of advanced ceramics with improved strength and insulating capacity.Type: GrantFiled: June 9, 1994Date of Patent: February 18, 1997Assignee: Martin Marietta Energy Systems, Inc.Inventors: Michael T. Harris, Osman A. Basaran, Warren G. Sisson, Ronald R. Brunson
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Patent number: 5503372Abstract: A nozzle for an electric dispersion reactor includes two coaxial cylindrical bodies, the inner one of the two delivering disperse phase fluid into a continuous phase fluid. A potential difference generated by a voltage source creates a dispersing electric field at the end of the inner electrode.Type: GrantFiled: August 18, 1994Date of Patent: April 2, 1996Assignee: Martin Marietta Energy Systems, Inc.Inventors: Warren G. Sisson, Michael T. Harris, Timothy C. Scott, Osman A. Basaran
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Patent number: 5480696Abstract: A powder evacuated thermal insulating panel using generally spherical and porous silica particles of a median size less than about 100 nanometers in diameter, a pour packing density of about 0.4 to 0.6 g/cm.sup.3 and an external surface area in the range of about 90 to 600 m.sup.2/ g is described. The silica powders are prepared by reacting a tetraakyl silicate with ammonia and water in an alcohol solvent, distilling the solution after the reaction to remove the ammonia and recover the alcohol. The resulting aqueous slurry was dried, ball-milled, and dried again to provide the silica particles with defined internal and external porosity. The nanometer size and the large external surface area of the silica particles along with the internal and external porosity of the silica particles provide powder evacuated thermal insulating panels with significantly higher R-values than obtainable using previously known silica powders.Type: GrantFiled: August 31, 1994Date of Patent: January 2, 1996Assignee: The United States of America as represented by the United States Department of EnergyInventors: Michael T. Harris, Osman A. Basaran, Thomas G. Kollie, Fred J. Weaver
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Patent number: 5464195Abstract: A nozzle for an electric dispersion reactor includes two concentric electrodes, the inner one of the two delivering disperse phase fluid into a continuous phase fluid. A potential difference generated by a voltage source creates a dispersing electric field at the end of the inner electrode.Type: GrantFiled: March 23, 1993Date of Patent: November 7, 1995Assignee: Martin Marietta Energy Systems, Inc.Inventors: Warren G. Sisson, Osman A. Basaran, Michael T. Harris
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Patent number: 5395604Abstract: A powder evacuated thermal insulating panel using generally spherical and porous silica particles of a median size less than about 100 nanometers in diameter, a pour packing density of about 0.4 to 0.6 g/cm.sup.3 and an external surface area in the range of about 90 to 600 m.sup.2/ g is described. The silica powders are prepared by reacting a tetraakyl silicate with ammonia and water in an alcohol solvent, distilling the solution after the reaction to remove the ammonia and recover the alcohol. The resulting aqueous slurry was dried, ball-milled, and dried again to provide the silica particles with defined internal and external porosity. The nanometer size and the large external surface area of the silica particles along with the internal and external porosity of the silica particles provide powder evacuated thermal insulating panels with significantly higher R-values than obtainable using previously known silica powders.Type: GrantFiled: May 3, 1994Date of Patent: March 7, 1995Assignee: Martin Marietta Energy Systems, Inc.Inventors: Michael T. Harris, Osman A. Basaran, Thomas G. Kollie, Fred J. Weaver
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Patent number: 5376449Abstract: A powder evacuated thermal insulating panel using generally spherical and porous silica particles of a median size less than about 100 nanometers in diameter, a pour packing density of about 0.4 to 0.6 g/cm.sup.3 and an external surface area in the range of about 90 to 600 m.sup.2 /g is described. The silica powders are prepared by reacting a tetraakyl silicate with ammonia and water in an alcohol solvent, distilling the solution after the reaction to remove the ammonia and recover the alcohol. The resulting aqueous slurry was dried, ball-milled, and dried again to provide the silica particles with defined internal and external porosity. The nanometer size and the large external surface area of the silica particles along with the internal and external porosity of the silica particles provide powder evacuated thermal insulating panels with significantly higher R-values than obtainable using previously known silica powders.Type: GrantFiled: July 9, 1993Date of Patent: December 27, 1994Assignee: Martin Marietta Energy Systems, Inc.Inventors: Michael T. Harris, Osman A. Basaran, Thomas G. Kollie, Fred J. Weaver