Abstract: A packaged skin treatment composition comprising: (a) a receptacle with a neck and having stored therein a treatment composition containing microscopic three dimensional spherical structures having membranous outer walls and secluded internal spaces, (b) a wiper affixed within the neck and having an internal barrel portion, (c) a closure for the receptacle, (d) an applicator comprised of a rod with a proximal end affixed to the closure and a distal end terminating in an enlarged portion, wherein when the rod is extracted from the receptacle the treatment composition loads onto the applicator in an amount sufficient to permit application of the treatment composition containing the microscopic spherical structures to the treatment surface.

Abstract: A sheet pack comprising an absorbent layer impregnated with a treatment composition containing at least one ingredient that when topically applied to skin stimulates a gene that is variably expressed over a 24 hour period in native untreated skin cells; the sheet pack contained in a package with user instructions to topically apply the sheet pack to the skin at a time when the gene that is stimulated by the ingredient is being maximally expressed in native untreated skin cells; and methods for treating skin and methods for making a sheet pack.

Abstract: A method for making a unit dose package containing a Pro-Resolution Pathway Stimulator that may be an Inflammatory Metabolite Inhibitor or a Pro-Resolving Activator or both, comprising testing active ingredients for activity in stimulating pro-resolution pathways and formulating actives into a composition that is packaged in a unit dose container for single use application.

Abstract: A packaged skin treatment composition comprising: (a) a receptacle with a neck and having stored therein a treatment composition containing microscopic three dimensional spherical structures having membranous outer walls and secluded internal spaces, (b) a wiper affixed within the neck and having an internal barrel portion, (c) a closure for the receptacle, (d) an applicator comprised of a rod with a proximal end affixed to the closure and a distal end terminating in an enlarged portion, wherein when the rod is extracted from the receptacle the treatment composition loads onto the applicator in an amount sufficient to permit application of the treatment composition containing the microscopic spherical structures to the treatment surface.

Abstract: A sheet pack comprising an absorbent layer impregnated with a treatment composition containing at least one ingredient that when topically applied to skin stimulates a gene that is variably expressed over a 24 hour period in native untreated skin cells; the sheet pack contained in a package with user instructions to topically apply the sheet pack to the skin at a time when the gene that is stimulated by the ingredient is being maximally expressed in native untreated skin cells; and methods for treating skin and methods for making a sheet pack.

Abstract: A sheet pack comprising an absorbent layer impregnated with a treatment composition containing at least one ingredient that when topically applied to skin stimulates a gene that is variably expressed over a 24 hour period in native untreated skin cells; the sheet pack contained in a package with user instructions to topically apply the sheet pack to the skin at a time when the gene that is stimulated by the ingredient is being maximally expressed in native untreated skin cells; and methods for treating skin and methods for making a sheet pack.

Abstract: A sheet pack comprising an absorbent layer impregnated with a treatment composition containing at least one ingredient that when topically applied to skin stimulates a gene that is variably expressed over a 24 hour period in native untreated skin cells; the sheet pack contained in a package with user instructions to topically apply the sheet pack to the skin at a time when the gene that is stimulated by the ingredient is being maximally expressed in native untreated skin cells; and methods for treating skin and methods for making a sheet pack.

Abstract: A sheet pack comprising an absorbent layer impregnated with a treatment composition containing at least one ingredient that when topically applied to skin stimulates a gene that is variably expressed over a 24 hour period in native untreated skin cells; the sheet pack contained in a package with user instructions to topically apply the sheet pack to the skin at a time when the gene that is stimulated by the ingredient is being maximally expressed in native untreated skin cells; and methods for treating skin and methods for making a sheet pack.

Abstract: A sheet pack comprising an absorbent layer impregnated with a treatment composition containing at least one ingredient that when topically applied to skin stimulates a gene that is variably expressed over a 24 hour period in native untreated skin cells; the sheet pack contained in a package with user instructions to topically apply the sheet pack to the skin at a time when the gene that is stimulated by the ingredient is being maximally expressed in native untreated skin cells; and methods for treating skin and methods for making a sheet pack.

Abstract: Ampoule containing a Pro-Resolution Pathway Stimulator, methods for making, and treating for skin having discrete areas of inflammation using ampoule composition containing Pro-Resolution Pathway Stimulator.

Abstract: A cosmetic applicator for a fluid material which comprises a container and a dispenser. Generally, the dispenser works by an actuating mechanism. In particular, a user depresses an ergonomically shaped top portion, which then actuates a pump that pumps a fluid cosmetic material from the lower portion of the container by means of a conduit through an aperture. The fluid cosmetic material pumped through the conduit and the aperture from the lower portion of the container rises through the conduit and saturates the closed cell sponge tip. The user then glides the closed cell sponge tip across her skin to apply the fluid cosmetic material. The cosmetic applicator is hermetically sealed with a cap, which can be removed by the user.

Abstract: The present invention provides a cosmetic applicator for a fluid material which comprises a container and a dispenser. Generally, the dispenser works by an actuating mechanism. In particular, a user depresses an ergonomically shaped top portion, which then actuates a pump that pumps a fluid cosmetic material from the lower portion of the container by means of a conduit through an aperture. The fluid cosmetic material pumped through the conduit and the aperture from the lower portion of the container rises through the conduit and saturates the closed cell sponge tip. The user then glides the closed cell sponge tip across her skin to apply the fluid cosmetic material. The cosmetic applicator is hermetically sealed with a cap, which can be removed by the user.