Abstract: The invention relates to pharmaceutically active substances from the group comprising midazolam and compounds with a methyl-substituted nitrogen atom that is the ring atom of a nitrogenous heterocycle. These substances are used to reduce the oxygen consumption during a physical activity. They can be administered together with an effective amount of D-glucose, D-maltose, ethanol, a glucogenic amine, a glucogenic amino acid or an amino acid metabolizable via glyoxylate or a dipeptide or a pharmaceutically acceptable salt of such an amino acid and an effective amount of thiamine, of a pharmaceutically acceptable thiamine salt or of a combination of folic acid and cyanocobalamine, with the proviso that the third component is thiamine or a pharmaceutically acceptable thiamine salt if the second component is D-glucose, D-maltose, a glucogenic amine, a glucogenic amino acid non-metabolizable via glyoxylate, or a dipeptide or a pharmaceutically acceptable salt of such an amino acid.

Abstract: The invention relates to a method of decreasing oxygen consumption during physical work and to preparations having such effect. The effect is achieved by administering efficient quantities of certain combinations of (a) D-glucose, D-maltose, ethanol, glucogenic amine, glucogenic amino acid or an amino acid metabolizable through glyoxal, or a dipeptide or pharmaceutically acceptable salt of such an amino acid, and (b) a vitamin components selected from thiamine, thiamine salts or combinations of folic acid and cyanocobalamin. Simultaneous administration of the combinations is efficient when taken prior to or during physical efforts or even one day before. Preferably, the combinations are administered in the form of gelled preparations containing a gelling agent.

Abstract: The invention relates to a method of decreasing oxygen consumption during physical work and to preparations having such effect. The effect is achieved by administering efficient quantities of certain combinations of (a) D-glucose, D-maltose, ethanol, glucogenic amine, glucogenic amino acid or an amino acid metabolizable through glyoxal, or a dipeptide or pharmaceutically acceptable salt of such an amino acid, and (b) a vitamin components selected from thiamine, thiamine salts or combinations of folic acid and cyanocobalamin. Simultaneous administration of the combinations is efficient when taken prior to or during physical efforts or even one day before. Preferably, the combinations are administered in the form of gelled preparations containing a gelling agent.