Patents by Inventor Otfried Kistner

Otfried Kistner has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Production of viral vaccine
    Patent number: 9884105
    Abstract: The present invention relates, in general, to materials and methods for production of an improved vaccine against influenza virus, wherein the vaccine comprises a reassortant virus having a hemagglutinin gene and a neuraminidase gene from the same influenza A virus subtype or influenza B strain of virus and internal genes from a different influenza A virus subtype or influenza B strain of virus. In one aspect, the HA and NA genes and the internal genes are from a highly pathogenic H5N1 strain of influenza A.
    Type: Grant
    Filed: December 16, 2009
    Date of Patent: February 6, 2018
    Assignee: OLOGY BIOSERVICES, INC.
    Inventors: Otfried Kistner, Falko-Guenter Falkner, Hartmut Ehrlich, Noel Barrett
  • ENVELOPED VIRUS VACCINE AND METHOD FOR PRODUCTION
    Publication number: 20170035874
    Abstract: The present invention provides methods of production of a purified enveloped virus antigen. In particular, it provides purified Ross River Virus (RRV) antigens, and vaccines comprising purified, inactivated Ross River Virus (RRV) antigen.
    Type: Application
    Filed: April 29, 2014
    Publication date: February 9, 2017
    Applicant: Baxter Healthcare SA
    Inventors: Otfried Kistner, Manfred Reiter, Axel Bruehmann, Noel Barrett, Wolfgang Mundt, Friedrich Dorner
  • ENVELOPED VIRUS VACCINE AND METHOD FOR PRODUCTION
    Publication number: 20160199478
    Abstract: The present invention provides methods of production of a purified enveloped virus antigen. In particular, it provides purified Ross River Virus (RRV) antigens, and vaccines comprising purified, inactivated Ross River Virus (RRV) antigen.
    Type: Application
    Filed: April 29, 2014
    Publication date: July 14, 2016
    Applicant: Baxter Healthcare SA
    Inventors: Otfried Kistner, Manfred Reiter, Axel Bruehmann, Noel Barrett, Wolfgang Mundt, Friedrich Dorner
  • Inactivation of a pathogen in a sample by a treatment with formalin and UV light
    Patent number: 8703467
    Abstract: The present invention relates to a method for inactivating virus in a sample by treating a virus containing sample with an effective concentration of formalin and by treating the sample with an effective dose of UV light in a flow-through apparatus.
    Type: Grant
    Filed: May 26, 2005
    Date of Patent: April 22, 2014
    Assignees: Baxter International Inc., Baxter Healthcare SA
    Inventors: Manfred Reiter, Wolfgang Mundt, Noel Barrett, Otfried Kistner
  • Method for Producing Viral Vaccines
    Publication number: 20130287811
    Abstract: The present invention provides a method for the manufacture of a preparation comprising virus antigens comprising a) inoculation of cells with infectious virus in a fluid, b) propagation of said virus in said cells, c) collecting said propagated virus, d) inactivating said collected virus, and e) treating said inactivated virus with a detergent, resulting in a preparation comprising viral antigens.
    Type: Application
    Filed: June 26, 2013
    Publication date: October 31, 2013
    Inventors: Otfried Kistner, Christa Tauer, P. Noel Barrett, Wolfgang Mundt
  • Method for producing viral vaccines
    Patent number: 8497112
    Abstract: The present invention provides a method for the manufacture of a preparation comprising virus antigens comprising a) inoculation of cells with infectious virus in a fluid, b) propagation of said virus in said cells, c) collecting said propagated virus, d) inactivating said collected virus, and e) treating said inactivated virus with a detergent, resulting in a preparation comprising viral antigens.
    Type: Grant
    Filed: August 28, 2008
    Date of Patent: July 30, 2013
    Assignees: Baxter International Inc., Baxter Healthcare SA
    Inventors: Otfried Kistner, Christa Tauer, Noel Barrett, Wolfgang Mundt
  • Vaccine to Influenza A Virus
    Publication number: 20110159031
    Abstract: The present invention relates, in general, to compositions and methods for administering a vaccine against influenza to a subject, the vaccine comprising a vaccinia virus vector and a hemagglutinin and neuraminidase gene, separate or in combination, from an influenza A virus.
    Type: Application
    Filed: December 22, 2010
    Publication date: June 30, 2011
    Applicants: BAXTER INTERNATIONAL INC., BAXTER HEALTHCARE S.A.
    Inventors: Falko G. Falkner, Otfried Kistner, Annett Hessel, P. Noel Barrett, Hartmut Ehrlich, Georg Holzer
  • Production of Viral Vaccine
    Publication number: 20100189745
    Abstract: The present invention relates, in general, to materials and methods for production of an improved vaccine against influenza virus, wherein the vaccine comprises a reassortant virus having a hemagglutinin gene and a neuraminidase gene from the same influenza A virus subtype or influenza B strain of virus and internal genes from a different influenza A virus subtype or influenza B strain of virus. In one aspect, the HA and NA genes and the internal genes are from a highly pathogenic H5N1 strain of influenza A.
    Type: Application
    Filed: December 16, 2009
    Publication date: July 29, 2010
    Applicants: BAXTER INTERNATIONAL INC., BAXTER HEALTHCARE S.A.
    Inventors: Otfried Kistner, Falko-Guenter Falkner, Hartmut Ehrlich, Noel Barrett
  • Method for Producing Viral Vaccines
    Publication number: 20090060950
    Abstract: The present invention provides a method for the manufacture of a preparation comprising virus antigens comprising a) inoculation of cells with infectious virus in a fluid, b) propagation of said virus in said cells, c) collecting said propagated virus, d) inactivating said collected virus, and e) treating said inactivated virus with a detergent, resulting in a preparation comprising viral antigens.
    Type: Application
    Filed: August 28, 2008
    Publication date: March 5, 2009
    Applicants: BAXTER INTERNATIONAL INC., BAXTER HEALTHCARE
    Inventors: Otfried Kistner, Christa Tauer, Noel Barrett, Wolfgang Mundt
  • Enveloped virus vaccine and method for production
    Publication number: 20070141617
    Abstract: The present invention provides methods of production of a purified enveloped virus antigen. In particular, it provides purified Ross River Virus (RRV) antigens, and vaccines comprising purified, inactivated Ross River Virus (RRV) antigen.
    Type: Application
    Filed: January 24, 2007
    Publication date: June 21, 2007
    Applicant: Baxter Healthcare S.A.
    Inventors: Otfried Kistner, Manfred Reiter, Axel Bruehmann, Noel Barrett, Wolfgang Mundt, Friedrich Dorner
  • Enveloped virus vaccine and method for production
    Patent number: 7195905
    Abstract: The present invention provides methods of production of a purified enveloped virus antigen. In particular, it provides purified Ross River Virus (RRV) antigens, and vaccines comprising purified, inactivated Ross River Virus (RRV) antigen.
    Type: Grant
    Filed: December 10, 2001
    Date of Patent: March 27, 2007
    Assignee: Baxter Healthcare S.A.
    Inventors: Otfried Kistner, Manfred Reiter, Axel Bruehmann, Noel Barrett, Wolfgang Mundt, Friedrich Dorner
  • Inactivation of a pathogen in a sample by a treatment with formalin and UV light
    Publication number: 20060270017
    Abstract: The present invention relates to a method for inactivating virus in a sample by treating a virus containing sample with an effective concentration of formalin and by treating the sample with an effective dose of UV light in a flow-through apparatus.
    Type: Application
    Filed: May 26, 2005
    Publication date: November 30, 2006
    Inventors: Manfred Reiter, Wolfgang Mundt, Noel Barrett, Otfried Kistner
  • Inactivated influenza virus vaccine for nasal or oral application
    Publication number: 20060147468
    Abstract: The invention relates to nasal or oral administration of a compound containing inactivated influenza virus antigen and aluminum as adjuvant for the prophylaxis of influenza virus infections. Said vaccine is especially suitable for inducing a mucosal IgA immune response and systemic IgG immune response.
    Type: Application
    Filed: March 2, 2006
    Publication date: July 6, 2006
    Applicant: Baxter Healthcare S.A.
    Inventors: Noel Barrett, Otfried Kistner, Marijan Gerencer, Friedrich Dorner
  • Inactivated influenza virus vaccine for nasal or oral application
    Patent number: 7052701
    Abstract: The invention relates to nasal or oral administration of a compound containing inactivated influenza virus antigen and aluminum as adjuvant for the prophylaxis of influenza virus infections. Said vaccine is especially suitable for inducing a mucosal IgA immune response and systemic IgG immune response.
    Type: Grant
    Filed: January 4, 2005
    Date of Patent: May 30, 2006
    Assignee: Baxter Healthcare S.A.
    Inventors: Noel Barrett, Otfried Kistner, Marijan Gerencer, Friedrich Dorner
  • Inactivated influenza virus vaccine for nasal or oral application
    Publication number: 20050196413
    Abstract: The invention relates to nasal or oral administration of a compound containing inactivated influenza virus antigen and aluminum as adjuvant for the prophylaxis of influenza virus infections. Said vaccine is especially suitable for inducing a mucosal IgA immune response and systemic IgG immune response.
    Type: Application
    Filed: January 4, 2005
    Publication date: September 8, 2005
    Applicant: Baxter Healthcare S.A.
    Inventors: Noel Barrett, Otfried Kistner, Marijan Gerencer, Friedrich Dorner
  • Inactivated influenza virus vaccine for nasal or oral application
    Patent number: 6861244
    Abstract: The invention relates to nasal or oral administration of a compound containing inactivated influenza virus antigen and aluminum as adjuvant for the prophylaxis of influenza virus infections. Said vaccine is especially suitable for inducing a mucosal IgA immune response and systemic IgG immune response.
    Type: Grant
    Filed: August 13, 2003
    Date of Patent: March 1, 2005
    Assignee: Baxter Healthcare S.A.
    Inventors: Noel Barrett, Otfried Kistner, Marijan Gerencer, Friedrich Dorner
  • Inactivated influenza virus vaccine for nasal or oral application
    Publication number: 20040096464
    Abstract: The invention relates to nasal or oral administration of a compound containing inactivated influenza virus antigen and aluminum as adjuvant for the prophylaxis of influenza virus infections. Said vaccine is especially suitable for inducing a mucosal IgA immune response and systemic IgG immune response.
    Type: Application
    Filed: August 13, 2003
    Publication date: May 20, 2004
    Applicant: Baxter Healthcare S.A.
    Inventors: Noel Barrett, Otfried Kistner, Marijan Gerencer, Friedrich Dorner
  • Inactivated influenza virus vaccine for nasal or oral application
    Patent number: 6635246
    Abstract: The invention relates to nasal or oral administration of a compound containing inactivated influenza virus antigen and aluminum as adjuvant for the prophylaxis of influenza virus infections. Said vaccine is especially suitable for inducing a mucosal IgA immune response and systemic IgG immune response.
    Type: Grant
    Filed: December 5, 2001
    Date of Patent: October 21, 2003
    Assignee: Baxter Healthcare S.A.
    Inventors: Noel Barrett, Otfried Kistner, Marijan Gerencer, Friedrich Dorner
  • Enveloped virus vaccine and method for production
    Publication number: 20030108859
    Abstract: The present invention provides methods of production of a purified enveloped virus antigen. In particular, it provides purified Ross River Virus (RRV) antigens, and vaccines comprising purified, inactivated Ross River Virus (RRV) antigen.
    Type: Application
    Filed: December 10, 2001
    Publication date: June 12, 2003
    Inventors: Otfried Kistner, Manfred Reiter, Axel Bruehmann, Noel Barrett, Wolfgang Mundt, Friedrich Dorner
  • Influenza virus vaccine composition
    Patent number: 6372223
    Abstract: This invention describes an influenza virus vaccine containing an influenza virus antigen obtained from a cell culture, with an influenza virus antigen content between 1 &mgr;g and 5 &mgr;g per dose and aluminum as an adjuvant as well as a method for its preparation.
    Type: Grant
    Filed: June 12, 2001
    Date of Patent: April 16, 2002
    Assignee: Baxter Aktiengesellschaft
    Inventors: Otfried Kistner, Noel Barrett, Wolfgang Mundt, Friedrich Dorner