Abstract: A pre-tied suturing knot for use with a surgical needle for endoscopic procedures and the method for making and using the pre-tied knot for tying the suture in situ. The pre-tied knot is tied from suturing thread and surrounds the shaft of a needle holder or grasper. A needle holder is placed on the U-shaped loop and the U-shaped loop or bight is pulled back upon itself to create a first loop, a second loop and two loopholes. The distal end of the suture thread is threaded over the proximal end and through the loopholes creating the nascent knot. The pre-tied knot is utilized after the tissue has been pierced with the needle. Thereafter, the needle holder is withdrawn from the suturing site, thereby pulling the suture thread against and through the tissue edges and moving the pre-tied knot along the shaft of the needle holder over the clamp and into position near the suturing site.