Patents by Inventor Otis C. ADDINGTON

Otis C. ADDINGTON has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20200222483
    Abstract: A method of treating viral infection, such as viral infection caused by a virus of the Filoviridae family, Flaviviridae family (Flavivirus genus), Deltaretrovirus genus, or Togaviriade family is provided. A composition having at least one cardiac glycoside is used to treat viral infection. The composition can futher include at least one triterpene. Alternatively, the composition comprises at least one, at least two, or at least three triterpenes.
    Type: Application
    Filed: March 20, 2020
    Publication date: July 16, 2020
    Applicant: PHOENIX BIOTECHNOLOGY, INC.
    Inventors: Robert A. NEWMAN, Otis C. ADDINGTON
  • Patent number: 10702567
    Abstract: A method of treating viral infection, such as viral infection caused by a virus of the Filoviridae family, Flaviviridae family (Flavivirus genus), Deltaretrovirus genus, or Togaviriade family is provided. A composition having at least one cardiac glycoside is used to treat viral infection. The composition can further include at least one triterpene. Alternatively, the composition comprises at least one, at least two, or at least three triterpenes.
    Type: Grant
    Filed: May 29, 2019
    Date of Patent: July 7, 2020
    Assignee: PHOENIX BIOTECHNOLOGY, INC.
    Inventors: Robert A. Newman, Otis C. Addington
  • Publication number: 20200206287
    Abstract: A method of treating viral infection, such as viral infection caused by a virus of the Filoviridae family, Flaviviridae family (Flavivirus genus), Deltaretrovirus genus, or Togaviriade family is provided. A composition having at least one cardiac glycoside is used to treat viral infection. The composition can further include at least one triterpene. Alternatively, the composition comprises at least one, at least two, or at least three triterpenes.
    Type: Application
    Filed: February 27, 2020
    Publication date: July 2, 2020
    Applicant: PHOENIX BIOTECHNOLOGY, INC.
    Inventors: Robert A. NEWMAN, Otis C. ADDINGTON
  • Publication number: 20200206288
    Abstract: A method of treating viral infection, such as viral infection caused by a virus of the Filoviridae family, Flaviviridae family (Flavivirus genus), Deltaretrovirus genus, or Togaviriade family is provided. A composition having at least one cardiac glycoside is used to treat viral infection. The composition can further include at least one triterpene. Alternatively, the composition comprises at least one, at least two, or at least three triterpenes.
    Type: Application
    Filed: March 11, 2020
    Publication date: July 2, 2020
    Applicant: PHOENIX BIOTECHNOLOGY, INC.
    Inventors: Robert A. NEWMAN, Otis C. ADDINGTON
  • Publication number: 20200179472
    Abstract: A method of treating viral infection, such as viral infection caused by a virus of the Filoviridae family, Flaviviridae family (Flavivirus genus), Deltaretrovirus genus, or Togaviriade family is provided. A composition having at least one cardiac glycoside is used to treat viral infection. The composition can futher include at least one triterpene. Alternatively, the composition comprises at least one, at leat two, or at least three triterpenes.
    Type: Application
    Filed: February 3, 2020
    Publication date: June 11, 2020
    Applicant: PHOENIX BIOTECHNOLOGY, INC.
    Inventors: Robert A. NEWMAN, Otis C. ADDINGTON
  • Publication number: 20200155630
    Abstract: A method of treating viral infection, such as viral infection caused by a virus of the Filoviridae family, Flaviviridae family (Flavivirus genus), Deltaretrovirus genus, or Togaviriade family is provided. A composition having at least one cardiac glycoside is used to treat viral infection. The composition can further include at least one triterpene. Alternatively, the composition comprises at least one, at least two, or at least three triterpenes.
    Type: Application
    Filed: January 21, 2020
    Publication date: May 21, 2020
    Applicant: PHOENIX BIOTECHNOLOGY, INC.
    Inventors: Robert A. NEWMAN, Otis C. ADDINGTON
  • Patent number: 10596186
    Abstract: A method of treating viral infection, such as viral infection caused by a virus of the Filoviridae, Flaviviridae or Togaviriade family, is provided. A composition having at least one cardiac glycoside is used to treat viral infection. The composition can further include at least one triterpene.
    Type: Grant
    Filed: February 14, 2019
    Date of Patent: March 24, 2020
    Assignee: PHOENIX BIOTECHNOLOGY, INC.
    Inventors: Robert A. Newman, Otis C. Addington
  • Publication number: 20190328809
    Abstract: A method of treating viral infection, such as viral infection caused by a virus of the Filoviridae family, Flaviviridae family (Flavivirus genus), Deltaretrovirus genus, or Togaviriade family is provided. A composition having at least one cardiac glycoside is used to treat viral infection. The composition can further include at least one triterpene. Alternatively, the composition comprises at least one, at least two, or at least three triterpenes.
    Type: Application
    Filed: May 29, 2019
    Publication date: October 31, 2019
    Applicant: PHOENIX BIOTECHNOLOGY, INC.
    Inventors: Robert A. NEWMAN, Otis C. ADDINGTON
  • Patent number: 10383886
    Abstract: A method of treating neurological condition in a subject by administration of a cardiac glycoside is provided. Alzheimer's disease, Huntington's disease or stroke are treated by administering a therapeutically effective amount of cardiac glycoside, and optionally triterpene(s), to a subject. The cardiac glycoside can be present in a dosage form.
    Type: Grant
    Filed: September 14, 2017
    Date of Patent: August 20, 2019
    Assignee: PHOENIX BIOTECHNOLOGY, INC.
    Inventors: Otis C. Addington, Robert A. Newman
  • Publication number: 20190240277
    Abstract: A method of treating neurological condition in a subject by administration of a neuroprotective composition of a mixture of two or more triterpenes. Alzheimer's disease, Huntington's disease, stroke or Parkinson's disease are treated by administering a therapeutically effective amount of the neuroprotective composition to a subject.
    Type: Application
    Filed: April 17, 2019
    Publication date: August 8, 2019
    Applicant: PHOENIX BIOTECHNOLOGY, INC.
    Inventors: OTIS C. ADDINGTON, ROBERT A. NEWMAN
  • Publication number: 20190175634
    Abstract: A method of treating viral infection, such as viral infection caused by a virus of the Filoviridae, Flaviviridae or Togaviriade family, is provided. A composition having at least one cardiac glycoside is used to treat viral infection. The composition can further include at least one triterpene.
    Type: Application
    Filed: February 14, 2019
    Publication date: June 13, 2019
    Applicant: PHOENIX BIOTECHNOLOGY, INC.
    Inventors: Robert A. NEWMAN, Otis C. ADDINGTON
  • Patent number: 10307450
    Abstract: A method of treating neurological condition in a subject by administration of a neuroprotective composition of a mixture of two or more triterpenes. Alzheimer's disease, Huntington's disease, stroke or Parkinson's disease are treated by administering a therapeutically effective amount of the neuroprotective composition to a subject.
    Type: Grant
    Filed: September 14, 2017
    Date of Patent: June 4, 2019
    Assignee: Phoenix Biotechnology, Inc.
    Inventors: Otis C. Addington, Robert A. Newman
  • Publication number: 20190076381
    Abstract: A method of treating a triterpene-responsive condition, disease or disorder in a subject by administration of an improved triterpene-based composition is provided. An improved triterpene-based composition comprising at least two or at least three triterpenes present at a molar ratio as described herein is also provided.
    Type: Application
    Filed: November 8, 2018
    Publication date: March 14, 2019
    Applicant: PHOENIX BIOTECHNOLOGY, INC.
    Inventors: ROBERT A. NEWMAN, OTIS C. ADDINGTON, DONALD C. LO, LINDA S. KALTENBACH
  • Patent number: 10226497
    Abstract: A method of treating neurological condition in a subject by administration of a pharmaceutical composition that excludes cardiac glycoside and excludes polysaccharide obtained from Nerium species or Thevetia species. Alzheimer's disease, Huntington's disease or stroke are treated by administering a therapeutically effective amount of the pharmaceutical composition to a subject.
    Type: Grant
    Filed: June 8, 2017
    Date of Patent: March 12, 2019
    Assignee: Phoenix Biotechnology, Inc.
    Inventors: Otis C. Addington, Robert A. Newman
  • Publication number: 20180042976
    Abstract: A method of treating neurological condition in a subject by administration of a neuroprotective composition of a mixture of two or more triterpenes. Alzheimer's disease, Huntington's disease, stroke or Parkinson's disease are treated by administering a therapeutically effective amount of the neuroprotective composition to a subject.
    Type: Application
    Filed: September 14, 2017
    Publication date: February 15, 2018
    Applicant: Phoenix Biotechnology, Inc.
    Inventors: Otis C. ADDINGTON, Robert A. NEWMAN
  • Patent number: 9877979
    Abstract: A method of treating neurological condition in a subject by administration of a cardiac glycoside is provided. Alzheimer's disease, Huntington's disease or stroke are treated by administering a therapeutically effective amount of cardiac glycoside to a subject. The cardiac glycoside can be present in a dosage form.
    Type: Grant
    Filed: May 2, 2016
    Date of Patent: January 30, 2018
    Assignee: Phoenix Biotechnology, Inc.
    Inventors: Otis C. Addington, Robert A. Newman
  • Publication number: 20180000852
    Abstract: A method of treating neurological condition in a subject by administration of a cardiac glycoside is provided. Alzheimer's disease, Huntington's disease or stroke are treated by administering a therapeutically effective amount of cardiac glycoside, and optionally triterpene(s), to a subject. The cardiac glycoside can be present in a dosage form.
    Type: Application
    Filed: September 14, 2017
    Publication date: January 4, 2018
    Applicant: PHOENIX BIOTECHNOLOGY, INC.
    Inventors: Otis C. ADDINGTON, Robert A. NEWMAN
  • Patent number: 9846156
    Abstract: A method of treatment employing cardiac glycoside is disclosed. A prognostic assay and kit and method of use thereof are provided. The kit and assay are used to determine the likelihood of a diseased cell or tissue having a therapeutic response to treatment with a cardiac glycoside in a disease having an etiology associated with excessive cell proliferation. The kit and assay are used to determine the ratio of isoforms of the ? subunit of Na, K-ATPase obtained from the diseased cell or tissue. The kit can be used to predict the therapeutic responsiveness of cancer or tumor in a subject to treatment with a cardiac glycoside. The kit and assay can be incorporated in a method of treating a disease or disorder having an etiology associated with excessive cell proliferation with a composition comprising a cardiac glycoside.
    Type: Grant
    Filed: October 21, 2016
    Date of Patent: December 19, 2017
    Inventors: Otis C. Addington, Peiying Yang, Robert A. Newman
  • Publication number: 20170274031
    Abstract: A method of treating neurological condition in a subject by administration of a pharmaceutical composition that excludes cardiac glycoside and excludes polysaccharide obtained from Nerium species or Thevetia species. Alzheimer's disease, Huntington's disease or stroke are treated by administering a therapeutically effective amount of the pharmaceutical composition to a subject.
    Type: Application
    Filed: June 8, 2017
    Publication date: September 28, 2017
    Applicant: Phoenix Biotechnology, Inc.
    Inventors: Otis C. ADDINGTON, Robert A. NEWMAN
  • Publication number: 20170067897
    Abstract: A method of treatment employing cardiac glycoside is disclosed. A prognostic assay and kit and method of use thereof are provided. The kit and assay are used to determine the likelihood of a diseased cell or tissue having a therapeutic response to treatment with a cardiac glycoside in a disease having an etiology associated with excessive cell proliferation. The kit and assay are used to determine the ratio of isoforms of the ? subunit of Na, K-ATPase obtained from the diseased cell or tissue. The kit can be used to predict the therapeutic responsiveness of cancer or tumor in a subject to treatment with a cardiac glycoside. The kit and assay can be incorporated in a method of treating a disease or disorder having an etiology associated with excessive cell proliferation with a composition comprising a cardiac glycoside.
    Type: Application
    Filed: October 21, 2016
    Publication date: March 9, 2017
    Applicant: PHOENIX BIOTECHNOLOGY, INC.
    Inventors: Otis C. ADDINGTON, Peiying YANG, Robert A. NEWMAN