Patents by Inventor Otto Behner

Otto Behner has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 5955482
    Abstract: The present invention relates to the use of 1,4-dihydropyridine-3,5-dicarboxylic acid esters, some of which are known, of the general formula (I) ##STR1## in which A and R.sup.1 -R.sup.3 have the meaning given in the description, as medicaments, in particular for treatment of the central nervous system, and new selected active compounds.
    Type: Grant
    Filed: March 28, 1997
    Date of Patent: September 21, 1999
    Assignee: Bayer Aktiengesellschaft
    Inventors: Klaus Urbahns, Otto Behner, Siegfried Goldmann, Hans-Georg Heine, Bodo Junge, Rudolf Schohe-Loop, Egbert Wehinger, Hartmund Wollweber, Henning Sommermeyer, Thomas Glaser, Reilinde Wittka, Jean-Marie-Viktor de Vry
  • Patent number: 5665741
    Abstract: The present invention relates to the use of 1,4-dihydropyridine-3,5-dicarboxylic acid esters, some of which are known, of the general formula (I) ##STR1## in which A and R.sup.1 -R.sup.3 have the meaning given in the description, as medicaments, in particular for treatment of the central nervous system, and new selected active compounds.
    Type: Grant
    Filed: August 18, 1995
    Date of Patent: September 9, 1997
    Assignee: Bayer Aktiengesellschaft
    Inventors: Klaus Urbahns, Otto Behner, Siegfried Goldmann, Hans-Georg Heine, Bodo Junge, Rudolf Schohe-Loop, Egbert Wehinger, Hartmund Wollweber, Henning Sommermeyer, Thomas Glaser, Reilinde Wittka, Jean-Marie-Viktor de Vry
  • Patent number: 5559139
    Abstract: The invention relates to the new dimethyl 4-(4-chloro-3-trifluoromethylphenyl) -1-cyclopropyl-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate, a process for its preparation and its use as a medicament in ischaemic diseases which are associated with disorders of the microcirculation. This action can occur both in the peripheral and in the cerebral vascular system.
    Type: Grant
    Filed: July 13, 1993
    Date of Patent: September 24, 1996
    Assignee: Bayer Aktiengesellschaft
    Inventors: Otto Behner, Hartmund Wollweber, Bruno Rosen, Siegfried Zaiss, Siegfried Goldmann
  • Patent number: 5432185
    Abstract: Improving circulation, with minimal effect on blood pressure, using N-alkylated 1,4-dihydropyridines of the formula ##STR1## in which R.sup.1 represents hydrogen, nitro, cyano, trifluoromethyl, trifluoromethoxy, halogen or methyl,R.sup.2 represents hydrogen, halogen, nitro, hydroxyl, trifluoromethyl or methyl,R.sup.3 represents hydrogen or cyano, orR.sup.2 and R.sup.3 together form a fused benzo ring,R.sup.4 and R.sup.5 are identical or different and represent straight-chain or branched alkyl having up to 8 carbon atoms, which is optionally substituted by alkoxy having up to 4 carbon atoms, andR.sup.6 represents straight-chain or branched alkyl having up to 10 carbon atoms or represents cycloalkyl having 3 to 7 carbon atoms.Many of the compounds are new.
    Type: Grant
    Filed: May 21, 1993
    Date of Patent: July 11, 1995
    Assignee: Bayer Aktiengesellschaft
    Inventors: Otto Behner, Hartmut Wollweber, Bruno Rosen, Siegfried Zaiss, Siegfried Goldmann
  • Patent number: 5342847
    Abstract: The invention relates to the new dimethyl 2,6-dimethyl-1-n-propyl-4-(trifluoro-methylphenyl)-1,4-dihydropyridine-3-d icarboxylate, a process for its preparation and its use as a medicament in ischaemic diseases which are associated with disorders of the microcirculation. This action can occur both in the peripheral and in the cerebral vascular system.
    Type: Grant
    Filed: January 16, 1993
    Date of Patent: August 30, 1994
    Assignee: Bayer Aktiengesellschaft
    Inventors: Otto Behner, Hartmund Wollweber, Siegfried Goldmann, Bruno Rosen, Siegfried Zaiss
  • Patent number: 5234935
    Abstract: Improving circulation, with minimal effect on blood pressure, using N-alkylated 1,4-dihydropyridines of the formula ##STR1## in which R.sup.1 represents hydrogen, nitro, cyano, trifluoromethyl, trifluoromethoxy, halogen or methyl,R.sup.2 represents hydrogen, halogen, nitro, hydroxyl, trifluoromethyl or methyl,R.sup.3 represents hydrogen or cyano, orR.sup.2 and R.sup.3 together form a fused benzo ring,R.sup.4 and R.sup.5 are identical or different and represent straight-chain or branched alkyl having up to 8 carbon atoms, which is optionally substituted by alkoxy having up to 4 carbon atoms, andR.sup.6 represents straight-chain or branched alkyl having up to 10 carbon atoms or represents cycloalkyl having 3 to 7 carbon atoms.Many of the compounds are new.
    Type: Grant
    Filed: April 4, 1991
    Date of Patent: August 10, 1993
    Assignee: Bayer Aktiengesellschaft
    Inventors: Otto Behner, Hartmut Wollweber, Bruno Rosen, Siegfried Zaiss, Siegfried Goldmann
  • Patent number: 4575501
    Abstract: 2-Arylhydrazino-2-thiazolines, acyl derivatives of these compounds and 2-arylazo-2-thiazolines, of the general formula ##STR1## and salts thereof, are new, are prepared as described and find use for combating ectoparasites and endoparasites, such as cattle and sheep ticks, and gastric and intestinal nematodes in ruminants and carnivors.
    Type: Grant
    Filed: August 6, 1982
    Date of Patent: March 11, 1986
    Assignee: Bayer Aktiengesellschaft
    Inventors: Otto Behner, Wilhelm Stendel, Peter Andrews
  • Patent number: 3993766
    Abstract: Acaricidal agents and compositions utilizing a 2-amino-.DELTA..sup.2 -thiazoline in which the amino group bears an ortho substituted phenyl group, naphth-l-yl, 5,6,7,8-tetrahydronaphth-l-yl or 1,3,5-trimethylpyrazol-4-yl, and salts thereof.
    Type: Grant
    Filed: March 28, 1975
    Date of Patent: November 23, 1976
    Assignee: Bayer Aktiengesellschaft
    Inventors: Otto Behner, Wilhelm Stendel
  • Patent number: 3989844
    Abstract: Oximes of the formula: ##SPC1##And their acid salts, wherein A is a branched or unbranched, saturated or unsaturated alkylene chain of 0-6 carbon atoms, B is a basic nitrogen-containing group such as an amino, alkylamino, dialkylamino, cycloalkylamino, dicycloalkylamino, cycloalkylalkylamino, dicycloalkylalkylamino, alkylarylamino, alkylaralkylamino, a piperidino, pyrrolidino, hexamethyleneimino, morpholino, thiomorpholino, N-alkylpiperazino or N-(2-hydroxyalkyl)-piperazino group, n is 1 or 2 and X is --CH.sub.2 --, --(CH.sub.2).sub.3 -- or --CH = CH--, and R.sub.1 and R.sub. 2 are each hydrogen, halogen, alkyl of 1-4 carbon atoms, alkoxy, alkylmercapto groups of 1-4 carbon atoms, hydroxyl, nitro, amino or trifluoromethyl, are useful for their anti-depressant activity. Pharmaceutical compositions may be prepared which comprise an anti-depressant amount of at least one such compound in combination with a pharmaceutically acceptable inert diluent or carrier.
    Type: Grant
    Filed: June 11, 1971
    Date of Patent: November 2, 1976
    Assignee: Bayer Aktiengesellschaft
    Inventors: Siegismund Schutz, Otto Behner, Friedrich Hoffmeister
  • Patent number: 3963778
    Abstract: 1. A compound selected from the group consisting ofAnd pharmaceutically acceptable non-toxic acid salts thereof.
    Type: Grant
    Filed: July 14, 1969
    Date of Patent: June 15, 1976
    Assignee: Bayer Aktiengesellschaft
    Inventors: Siegismund Schutz, Otto Behner, Friedrich Hoffmeister
  • Patent number: 3936463
    Abstract: Benzomorphanes of the formula: ##SPC1##WhereinR is cyclopropylmethyl or cyclobutylmethyl;R.sup.1 and R.sup.2 are the same or different and each is lower alkyl;R.sup.
    Type: Grant
    Filed: December 3, 1973
    Date of Patent: February 3, 1976
    Assignee: Bayer Aktiengesellschaft
    Inventors: Otto Behner, Ulrich Horlein, Friedrich Hoffmeister, Hans Werner Schubert