Patents by Inventor Otto O. Yang, Ph.D.

Otto O. Yang, Ph.D. has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Chimeric Antigen Receptors against Human Cytomegalovirus
    Publication number: 20240082403
    Abstract: Disclosed herein are CMV-specific CARs. In some embodiments. the present invention is directed to a method of treating, reducing, or inhibiting an infection by a cytomegalovirus in a subject, which comprises administering to the subject (a) an expression vector that encodes a CMV-specific CAR as described herein, or (b) one or more cells that are transduced with the expression vector.
    Type: Application
    Filed: October 12, 2020
    Publication date: March 14, 2024
    Inventors: Otto O. Yang, Ph.D., Ayub Ali, Don J. Diamond, Flavia Chiuppesi, Felix Wussow
  • Fusion Fragment Chimeric Antigen Receptors and Uses Thereof
    Publication number: 20210252068
    Abstract: Disclosed herein are fusion fragment chimeric antigen receptors (FF-CARs), engineered cells expressing FF-CARs, and methods of using thereof to treat, reduce, or inhibit infections by enveloped viruses in subjects.
    Type: Application
    Filed: June 13, 2019
    Publication date: August 19, 2021
    Inventors: Otto O. Yang, Ph.D., Balamurugan Arumugam
  • Vault Particles Having a Modified R8 Flexible Region
    Publication number: 20200255488
    Abstract: Disclosed herein are major vault proteins having modified R8 flexible regions, vault particles comprising major vault proteins having modified R8 flexible regions, and methods of packaging passenger polypeptides in the modified R8 flexible regions.
    Type: Application
    Filed: October 30, 2018
    Publication date: August 13, 2020
    Inventors: Otto O. Yang, Ph.D., Ke Ding, Jan Mrazek, Ph.D., Z. Hong Zhou, Ph.D.
  • Methods for Selectively Expanding and Enriching Cells Transduced with Chimeric Antigen Receptors and Treating HIV Infection
    Publication number: 20190024049
    Abstract: Disclosed herein are methods for selectively expanding cells expressing chimeric antigen receptors and enriching cells expressing chimeric antigen receptors in compositions and methods of treating HIV infection in subjects by administering the expanded and/or enriched cells.
    Type: Application
    Filed: January 27, 2017
    Publication date: January 24, 2019
    Applicant: The Regents of the University of California
    Inventors: Otto O. Yang, Ph.D., Ayub Ali, Hwee Ng, Scott G. Kitchen, Jerome A. Zack, Irvin Chen