Patents by Inventor Otto Saiko

Otto Saiko has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 4654350
    Abstract: Imidazo(4,5-c)pyridines of the formula ##STR1## wherein X is O, S or NH;Y is --NR.sup.2 --CH.dbd.N-- or --N.dbd.CH--NR.sup.2 --;R.sup.1 is 1-benzothienylmethyl, naphthylmethyl, or benzyl which is mono- or di-substituted by F, Cl, NO.sub.2, CF.sub.3 or a combination thereof, and;R.sup.2 is alkyl of 1-4 C atoms or cyclopropylmethyl,or a physiologically acceptable acid addition salt thereof,have valuable pharmacological activity, e.g., as GABA agonists.
    Type: Grant
    Filed: June 12, 1986
    Date of Patent: March 31, 1987
    Assignee: Merck Patent Gesellschaft Mit Beschrankter Haftung
    Inventors: Klaus Irmscher, Otto Saiko, Klaus-Otto Minck, Hans-Peter Wolf
  • Patent number: 4251538
    Abstract: Indolealkylamines of the formula ##STR1## wherein Ind is 1-R.sup.4 -2-R.sup.5 -indol-3-yl or the corresponding group in which the benzene ring is monosubstituted to trisubstituted by alkyl, O-alkyl, S-alkyl, OH, F, Cl, Br, CF.sub.3 or CN; A is --(CH.sub.2).sub.4 --, --(CH.sub.2).sub.3 --CO-- or --CO--(CH.sub.2).sub.2 --CO--; R.sup.1 is H or methyl; R.sup.2 is H or together with R.sup.3 is a C--C bond; R.sup.3 is H or together with R.sup.2 is a C--C bond; R.sup.4 and R.sup.5 are each H, alkyl, or phenyl; and Ar is phenyl or phenyl monosubstituted or disubstituted by alkyl, F, Cl, Br, I or CF.sub.3 ; wherein alkyl in each case is of 1-4 carbon atoms;and the physiologically acceptable acid addition salts thereof possess valuable pharmacological properties.
    Type: Grant
    Filed: June 22, 1979
    Date of Patent: February 17, 1981
    Assignee: Merck Patent Gesellschaft mit beschrankter Haftung
    Inventors: Hans-Heinrich Hausberg, Volker Koppe, Eike Poetsch, Otto Saiko, Christoph Seyfried