Patents by Inventor Otto Schuster

Otto Schuster has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 6066332
    Abstract: A medicament for immediately treating painful, inflammatory and/or febrile diseases contains as active substance ibuprofen as a racemate, as a racemic mixture with its enantiomers, as a pseudoracemate (mixtures of equal parts of S- and R-ibuprofen) or as a mixture of different parts of S- and R-ibuprofen in a range between pure S- and pure R-ibuprofen in the form of a pharmaceutically applicable nanosol and satisfies all requirements of an immediate-effect pharmaceutic form. It can in addition be combined with a slow-release medicament that contains as active substance ibuprofen as a racemic compound, as a pseudoracemate (mixtures of equal parts of S- and R-ibuprofen) or as a mixture of different parts of S- and R-ibuprofen in a range between pure S- and pure R-ibuprofen, in the form of a pharmaceutically applicable, gelatine-based nanosol.
    Type: Grant
    Filed: December 1, 1995
    Date of Patent: May 23, 2000
    Assignees: Alfatec-Pharma GmbH, PAZ Arzneimittelentwicklungsgesellschaft mbH
    Inventors: Jens-Christian Wunderlich, Otto Schuster, Helmut Lukas, Ursula Schick
  • Patent number: 5844135
    Abstract: A temperature sensor for measuring and/or monitoring the temperature of a medium flowing in a flow conduit of an internal combustion engine. The sensor has a one-piece plastic body with a sensor and plug part, a resistor element, connecting plug tongues, and a housing that receives the sensor part. In order to reduce production and installation costs and to attain other advantages as well, the housing is of temperature-resistant plastic that absorbs little moisture, sprayed directly onto the sensor part. For sealingly and securing the housing in a receiving bore in the wall of the flow conduit, a radially protruding annular bead is injection molded to the housing, and a sealing ring is plastic between the plug part and the annular bead.
    Type: Grant
    Filed: September 20, 1996
    Date of Patent: December 1, 1998
    Assignee: Robert Bosch GmbH
    Inventors: Hartmut Brammer, Joachim Kuhrau, Otto Schuster, Walter Schieferle, Anita Rose, Bernd Kuenzl, Hermann Bundschuh, Herbert Biederwolf
  • Patent number: 5560924
    Abstract: Immediate-effect medicaments containing a pharmacologically active 2-arylpropionic acid derivate as a pharmaceutically applicable nanosol have a considerably improved action start and bioavailability of the active substance. The 2-arylpropionic acid derivates, for example ibuprofen, flurbiprofen and ketoprofen, that are scarcely soluble in an aqueous medium, are present in a gelatine-stabilized nanosol in a form that allows these active substances to be quickly and completely resorbed already in the stomach. The disclosed colloidal disperse system composed of a 2-arylpropionic acid derivate is prepared by selecting a gelatine or gelatine derivate according to their isoelectric point (IEP), so that their IEP is adapted to the charge of the 2-arylpropionic acid derivate particles, leading to a neutral charge when the gelatine or its derivate is combined with the undissolved 2-arylpropionic acid derivate at a determined pH value.
    Type: Grant
    Filed: September 29, 1994
    Date of Patent: October 1, 1996
    Assignees: Alfatec-Pharma GmbH, PAZ Arzneimittelentwicklungsgesell schaft mbH
    Inventors: Jens-Christian Wunderlich, Ursula Schick, Jurgen Werry, Jurgen Freidenreich, Helmut Lukas, Otto Schuster
  • Patent number: 5556638
    Abstract: A medicament for immediately treating painful, inflammatory and/or febrile acute diseases contains flurbiprofen as a racemate, a mixture of a racemate with its enantiomers, a pseudoracemate (mixtures of equal parts of S- and R-flurbiprofen) or as a mixture of different parts of S- and R-flurbiprofen in the range extending between pure S and pure R-flurbiprofen as active substance in the form of a pharmaceutically applicable nanosol. This medicament satisfies all requirements of an immediate-effect pharmaceutic form.
    Type: Grant
    Filed: September 16, 1994
    Date of Patent: September 17, 1996
    Assignee: Alfatec Pharma GMBH
    Inventors: Jens-Christian Wunderlich, Otto Schuster, Helmut Lukas, Ursula Schick
  • Patent number: 5541227
    Abstract: An ibuprofen-containing medicament which contains ibuprofen only in the (S)-(+)-form is disclosed. (S)-(+)-ibuprofen is more than twice as active as the racemate which has until now been used in the treatment of rheumatism. This permits reduction of the quantity of active ingredient and the size of the tablets or dragees.
    Type: Grant
    Filed: January 24, 1991
    Date of Patent: July 30, 1996
    Assignee: Johnson & Johnson - Merck Pharmaceuticals Co.
    Inventors: Dieter Loew, Otto Schuster, H. Lucas
  • Patent number: 5519057
    Abstract: An ibuprofen-containing medicament which contains ibuprofen only in the (S)-(+)-form is disclosed. (S)-(+)ibuprofen is more than twice as active as the racemate which has until now been used in the treatment of rheumatism. This permits reduction of the quantity of active ingredient and the size of the tablets or dragees.
    Type: Grant
    Filed: September 11, 1989
    Date of Patent: May 21, 1996
    Assignee: Johnson & Johnson--Merck Pharmaceuticals Co.
    Inventors: Dieter Loew, Otto Schuster, H. Lukas
  • Patent number: 4983765
    Abstract: A process is described in which a mixture of enantiomeric arylpropionic acid is split and one of enantiomeric forms of the acid is recovered. The mixture is transformed into a diastereoisomeric salt by a reaction with a chiralic base and an inert solvent, and the desired acid enantiomer is removed from the reaction product. The transformation to a diastereoisomeric salt takes place in a polar solvent. The salt produced is recrystallized several times and the thus purified salt is split in a dilute mineral acid.
    Type: Grant
    Filed: June 27, 1989
    Date of Patent: January 8, 1991
    Assignee: PAZ Arzneimittel-Entwicklungsgesellschaft mbH
    Inventors: Helmut Lukas, Otto Schuster, Gunther Rau
  • Patent number: 4877620
    Abstract: An ibuprofen-containing medicament which contains ibuprofen only in the (S)-(+)-form is disclosed. (S)-(+)-ibuprofen is more than twice as active as the racemate which has until now been used in the treatment of rheumatism. This permits reduction of the quantity of active ingredient and the size of the tablets or dragees.
    Type: Grant
    Filed: November 10, 1987
    Date of Patent: October 31, 1989
    Assignee: MEDICE Chem.- Pharm. Fabrik Putter GmbH & Co. KG
    Inventors: Dieter Loew, Otto Schuster, H. Lukas
  • Patent number: 4425117
    Abstract: A device for the release of a substance at a defined or desired location in the alimentary tract. The device has a capsule having a separating wall therein, which forms a first chamber and a second chamber in the capsule. A hole is present in the wall of the first chamber. A compression spring, that is in a compressed state, is affixed to a body located in the second chamber. A needle is mounted on the compression spring facing the separation wall. A resonant circuit, in the second chamber, is tuned to an electromagnetic field of high frequency. The resonant circuit has a coupling coil, positioned around the body, a capacitor, connected to the other end of the coil and extending away from the first chamber, and a resistance wire, attached to the coupling coil and the capacitor. A fuse wire is connected to the compression spring, extends through the longitudinal passageway of the body and is connected to the body end facing away from the first chamber. The fuse wire contacts the resistance wire.
    Type: Grant
    Filed: December 2, 1981
    Date of Patent: January 10, 1984
    Assignee: Battelle-Institut e.V.
    Inventors: Berhhard Hugemann, Otto Schuster