Patents by Inventor Ottrina S. Bond

Ottrina S. Bond has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compositions and methods for selective inhibition of VEGF
    Patent number: 8470792
    Abstract: Disclosed herein are siRNA compositions and methods useful for inhibiting expression of vascular endothelial growth factor (VEGF) isoforms. Such compositions and methods further involve siRNA capable of selectively targeting angiogenic VEGF isoforms while selectively sparing anti-angiogenic isoforms. Diseases which involve angiogenesis stimulated by overexpression of VEGF, such as diabetic retinopathy, age related macular degeneration and many types of cancer, can be treated by administering small interfering RNAs as disclosed.
    Type: Grant
    Filed: December 4, 2009
    Date of Patent: June 25, 2013
    Assignee: Opko Pharmaceuticals, LLC.
    Inventors: Phillip Frost, Nadine Dejneka, Ottrina S. Bond, Naveed Shams
  • COMPOSITIONS AND METHODS FOR SELECTIVE INHIBITION OF VEGF
    Publication number: 20100151007
    Abstract: Disclosed herein are siRNA compositions and methods useful for inhibiting expression of vascular endothelial growth factor (VEGF) isoforms. Such compositions and methods further involve siRNA capable of selectively targeting angiogenic VEGF isoforms while selectively sparing anti-angiogenic isoforms. Diseases which involve angiogenesis stimulated by overexpression of VEGF, such as diabetic retinopathy, age related macular degeneration and many types of cancer, can be treated by administering small interfering RNAs as disclosed.
    Type: Application
    Filed: December 4, 2009
    Publication date: June 17, 2010
    Applicant: OPKO OPHTHALMICS, LLC
    Inventors: Phillip Frost, Nadine Dejneka, Ottrina S. Bond, Naveed Shams