Patents by Inventor Outi Koivistoinen

Outi Koivistoinen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11655478
    Abstract: The present invention relates to a novel promoter for regulating ADH gene expression in an organic acid-resistant yeast, and a method of producing an organic acid by expressing an organic acid production-related gene using the same. When an organic acid production-related target gene is expressed in the organic acid-resistant yeast using the novel promoter according to the present invention, there is an advantage in that the yeast can produce the organic acid with high efficiency while having resistance to the organic acid without inhibiting the growth ability of the yeast.
    Type: Grant
    Filed: February 28, 2019
    Date of Patent: May 23, 2023
    Assignee: SK Innovation Co., Ltd.
    Inventors: Jae Yeon Park, Tae Young Lee, Ki Sung Lee, Outi Koivistoinen, Kari Koivuranta
  • Publication number: 20230111619
    Abstract: The present invention relates to the fields of life sciences, genetics and regulation of gene expression. Specifically, the invention relates to a non-viral transcription activation domain for a eukaryotic host. Also, the present invention relates to a polypeptide or artificial transcription factor comprising the transcription activation domain of the present invention. And furthermore, the present invention relates to a polynucleotide, an expression cassette, expression system, and/or a eukaryotic host. Still, the present invention relates to a method for producing a desired protein product in the eukaryotic host of the present invention or to a method of preparing a non-viral transcription activation domain of the present invention or a polynucleotide encoding said non-viral transcription activation domain.
    Type: Application
    Filed: November 18, 2020
    Publication date: April 13, 2023
    Inventors: Dominik MOJZITA, Outi KOIVISTOINEN, Astrid SALUMÄE
  • Patent number: 11254922
    Abstract: Provided are a novel isoprene synthase derived from sweet potato and a method of preparing isoprene using the same, and more specifically, a novel isoprene synthase derived from sweet potato, a gene encoding the isoprene synthase, a host cell transformed with the gene, and a method of preparing isoprene using the same. The isoprene synthase of the present invention may have higher isoprene productivity as compared to isoprene synthases known in the related art to thereby be effectively used in isoprene biosynthesis and preparation of an isoprene polymer using the same.
    Type: Grant
    Filed: March 15, 2019
    Date of Patent: February 22, 2022
    Assignee: SK Innovation Co., Ltd.
    Inventors: Merja Oja, Anne Huuskonen, Marja Ilmén, Jae Hoon Jo, Simon MoonGeun Jung, Outi Koivistoinen, Sang Min Lee, Laura Ruohonen
  • Publication number: 20210108216
    Abstract: The present invention relates to a novel promoter for regulating ADH gene expression in an organic acid-resistant yeast, and a method of producing an organic acid by expressing an organic acid production-related gene using the same. When an organic acid production-related target gene is expressed in the organic acid-resistant yeast using the novel promoter according to the present invention, there is an advantage in that the yeast can produce the organic acid with high efficiency while having resistance to the organic acid without inhibiting the growth ability of the yeast.
    Type: Application
    Filed: February 28, 2019
    Publication date: April 15, 2021
    Inventors: Jae Yeon PARK, Tae Young LEE, Ki Sung LEE, Outi KOIVISTOINEN, Kari KOIVURANTA
  • Patent number: 10704064
    Abstract: Provided are a recombinant yeast producing 3-hydroxypropionic acid (3-HP) and a method for producing 3-HP using the same, more particularly, a recombinant yeast producing 3-HP, comprising an exogenous AADH gene; an endogenous or exogenous ACC gene; an exogenous MCR gene; and an exogenous HPDH gene, and producing 3-HP through [Pyruvate Acetaldehyde?Acetyl-CoA Malonyl-CoA Malonate semialdehyde 3-HP] biosynthesis pathway, and a method for producing 3-HP using the same.
    Type: Grant
    Filed: August 28, 2015
    Date of Patent: July 7, 2020
    Assignee: SK Innovation Co., Ltd.
    Inventors: Joong Min Park, Jae Yeon Park, Woo Chan Park, Sang Min Lee, Young Bin Seo, Merja Oja, Outi Koivistoinen, Andrew Conley, Marja Ilmen, Laura Ruohonen, Paula Jouhten
  • Publication number: 20190203193
    Abstract: Provided are a novel isoprene synthase derived from sweet potato and a method of preparing isoprene using the same, and more specifically, a novel isoprene synthase derived from sweet potato, a gene encoding the isoprene synthase, a host cell transformed with the gene, and a method of preparing isoprene using the same. The isoprene synthase of the present invention may have higher isoprene productivity as compared to isoprene synthases known in the related art to thereby be effectively used in isoprene biosynthesis and preparation of an isoprene polymer using the same.
    Type: Application
    Filed: March 15, 2019
    Publication date: July 4, 2019
    Inventors: Merja Oja, Anne Huuskonen, Marja Ilmén, Jae Hoon Jo, Simon MoonGeun Jung, Outi Koivistoinen, Sang Min Lee, Laura Ruohonen
  • Patent number: 10287565
    Abstract: Provided are a novel isoprene synthase derived from sweet potato and a method of preparing isoprene using the same, and more specifically, a novel isoprene synthase derived from sweet potato, a gene encoding the isoprene synthase, a host cell transformed with the gene, and a method of preparing isoprene using the same. The isoprene synthase of the present invention may have higher isoprene productivity as compared to isoprene synthases known in the related art to thereby be effectively used in isoprene biosynthesis and preparation of an isoprene polymer using the same.
    Type: Grant
    Filed: July 28, 2015
    Date of Patent: May 14, 2019
    Assignee: SK Innovation Co., Ltd.
    Inventors: Merja Oja, Anne Huuskonen, Marja Iimen, Laura Ruohonen, Outi Koivistoinen, Simon Moon Geun Jung, Jae Hoon Jo, Sang Min Lee
  • Patent number: 9783809
    Abstract: The present invention concerns a eukaryotic host selected from microorganisms, and a method for producing glycolic acid using said eukaryotic host cells, especially cells of a genetically modified fungal host. Further this invention relates to a glycolic acid product obtained using the method described here and the use of genetically modified microorganism cells in production of glycolic acid.
    Type: Grant
    Filed: October 4, 2012
    Date of Patent: October 10, 2017
    Assignee: Teknologian tutkimuskeskus VTT Oy
    Inventors: Outi Koivistoinen, Joosu Kuivanen, Peter Richard, Merja Penttilä
  • Publication number: 20170240932
    Abstract: Provided are a recombinant yeast producing 3-hydroxypropionic acid (3-HP) and a method for producing 3-HP using the same, more particularly, a recombinant yeast producing 3-HP, comprising an exogenous AADH gene; an endogenous or exogenous ACC gene; an exogenous MCR gene; and an exogenous HPDH gene, and producing 3-HP through [Pyruvate Acetaldehyde?Acetyl-CoA Malonyl-CoA Malonate semialdehyde 3-HP] biosynthesis pathway, and a method for producing 3-HP using the same.
    Type: Application
    Filed: August 28, 2015
    Publication date: August 24, 2017
    Inventors: Joong Min Park, Jae Yeon Park, Woo Chan Park, Sang Min Lee, Young Bin Seo, Merja Oja, Outi Koivistoinen, Andrew Conley, Marja Ilmen, Laura Ruohonen, Paula Jouhten
  • Publication number: 20170211056
    Abstract: Provided are a novel isoprene synthase derived from sweet potato and a method of preparing isoprene using the same, and more specifically, a novel isoprene synthase derived from sweet potato, a gene encoding the isoprene synthase, a host cell transformed with the gene, and a method of preparing isoprene using the same. The isoprene synthase of the present invention may have higher isoprene productivity as compared to isoprene synthases known in the related art to thereby be effectively used in isoprene biosynthesis and preparation of an isoprene polymer using the same.
    Type: Application
    Filed: July 28, 2015
    Publication date: July 27, 2017
    Inventors: Merja Oja, Anne Huuskonen, Marja Iimen, Laura Ruohonen, Outi Koivistoinen, Simon Moon Geun Jung, Jae Hoon Jo, Sang Min Lee
  • Publication number: 20140295510
    Abstract: The present invention concerns a eukaryotic host selected from microorganisms, and a method for producing glycolic acid using said eukaryotic host cells, especially cells of a genetically modified fungal host. Further this invention relates to a glycolic acid product obtained using the method described here and the use of genetically modified microorganism cells in production of glycolic acid.
    Type: Application
    Filed: October 4, 2012
    Publication date: October 2, 2014
    Inventors: Outi Koivistoinen, Joosu Kuivanen, Peter Richard, Merja Penttilä