Patents by Inventor Owen Anthony O'CONNOR

Owen Anthony O'CONNOR has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • HISTONE ACETYLTRANSFERASE ACTIVATORS AND COMPOSITIONS AND USES THEREOF
    Publication number: 20230165813
    Abstract: The invention provides pharmaceutical compositions and methods for treating cancer, neurodegenerative disorders, conditions associated with accumulated amyloid-beta peptide deposits, Tau protein levels, and/or accumulations of alpha-synuclein by administering a HAT modulator and a HDAC modulator to a subject.
    Type: Application
    Filed: August 4, 2022
    Publication date: June 1, 2023
    Inventors: Owen Anthony O'CONNOR, Jennifer Effie AMENGUAL, Donald W. LANDRY, Ottavio ARANCIO, Luigi SCOTTO, Shixian DENG, Rosa PURGATORIO, Jole FIORITO
  • Histone acetyltransferase activators and compositions and uses thereof
    Patent number: 11406608
    Abstract: The invention provides pharmaceutical compositions and methods for treating cancer, neurodegenerative disorders, conditions associated with accumulated amyloid-beta peptide deposits, Tau protein levels, and/or accumulations of alpha-synuclein by administering a HAT modulator and a HDAC modulator to a subject.
    Type: Grant
    Filed: May 8, 2020
    Date of Patent: August 9, 2022
    Assignee: THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK
    Inventors: Owen Anthony O'Connor, Jennifer Effie Amengual, Donald W. Landry, Ottavio Arancio, Luigi Scotto, Shixian Deng, Rosa Purgatorio, Joie Fiorito
  • Histone acetyltransferase activators and uses thereof
    Patent number: 11191768
    Abstract: The invention provides compounds and compositions comprising compounds that modulate histone acyl transferase (HAT). The invention further provides methods for treating neurodegenerative disorders, conditions associated with accumulated amyloid-beta peptide deposits, Tau protein levels, and/or accumulations of alpha-synuclein as well as cancer by administering a compound that modulates HAT to a subject.
    Type: Grant
    Filed: December 2, 2019
    Date of Patent: December 7, 2021
    Assignee: The Trustees of Columbia University in the City of New York
    Inventors: Ottavio Arancio, Shixian Deng, Donald W. Landry, Jole Fiorito, Rosa Purgatorio, Owen Anthony O'Connor, Jennifer Effie Amengual
  • HISTONE ACETYLTRANSFERASE ACTIVATORS AND COMPOSITIONS AND USES THEREOF
    Publication number: 20200330410
    Abstract: The invention provides pharmaceutical compositions and methods for treating cancer, neurodegenerative disorders, conditions associated with accumulated amyloid-beta peptide deposits, Tau protein levels, and/or accumulations of alpha-synuclein by administering a HAT modulator and a HDAC modulator to a subject.
    Type: Application
    Filed: May 8, 2020
    Publication date: October 22, 2020
    Inventors: Owen Anthony O'CONNOR, Jennifer Effie AMENGUAL, Donald W. LANDRY, Ottavio ARANCIO, Luigi SCOTTO, Shixian DENG, Rosa PURGATORIO, Jole FIORITO
  • Histone acetyltransferase activators and compositions and uses thereof
    Patent number: 10653648
    Abstract: The invention provides pharmaceutical compositions and methods for treating cancer, neurodegenerative disorders, conditions associated with accumulated amyloid-beta peptide deposits, Tau protein levels, and/or accumulations of alpha-synuclein by administering a HAT modulator and a HDAC modulator to a subject.
    Type: Grant
    Filed: July 20, 2017
    Date of Patent: May 19, 2020
    Assignee: THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK
    Inventors: Owen Anthony O'Connor, Jennifer Effie Amengual, Donald W. Landry, Ottavio Arancio, Luigi Scotto, Shixian Deng, Rosa Purgatorio, Jole Fiorito
  • HISTONE ACETYLTRANSFERASE ACTIVATORS AND USES THEREOF
    Publication number: 20200101078
    Abstract: The invention provides compounds and compositions comprising compounds that modulate histone acyl transferase (HAT). The invention further provides methods for treating neurodegenerative disorders, conditions associated with accumulated amyloid-beta peptide deposits, Tan protein levels, and/or accumulations of alpha-synuclein as well as cancer by administering a compound that modulates HAT to a subject.
    Type: Application
    Filed: December 2, 2019
    Publication date: April 2, 2020
    Inventors: Ottavio ARANCIO, Shixian DENG, Donald W. LANDRY, Jole FIORITO, Rosa PURGATORIO, Owen Anthony O'CONNOR, Jennifer Effie AMENGUAL
  • Histone Acetyltransferase Activators and Uses Thereof
    Publication number: 20180360842
    Abstract: The invention provides compounds and compositions comprising compounds that modulate histone acyl transferase (HAT). The invention further provides methods for treating neurodegenerative disorders, conditions associated with accumulated amyloid-beta peptide deposits, Tau protein levels, and/or accumulations of alpha-synuclein as well as cancer by administering a compound that modulates HAT to a subject.
    Type: Application
    Filed: January 11, 2018
    Publication date: December 20, 2018
    Inventors: Ottavio ARANCIO, Shi Xian DENG, Donald W. LANDRY, Jole FIORITO, Rosa PURGATORIO, Owen Anthony O'CONNOR, Jennifer Effie AMENGUAL
  • HISTONE ACETYLTRANSFERASE ACTIVATORS AND COMPOSITIONS AND USES THEREOF
    Publication number: 20180021273
    Abstract: The invention provides pharmaceutical compositions and methods for treating cancer, neurodegenerative disorders, conditions associated with accumulated amyloid-beta peptide deposits, Tau protein levels, and/or accumulations of alpha-synuclein by administering a HAT modulator and a HDAC modulator to a subject.
    Type: Application
    Filed: July 20, 2017
    Publication date: January 25, 2018
    Inventors: Owen Anthony O'CONNOR, Jennifer Effie AMENGUAL, Donald W. LANDRY, Ottavio ARANCIO, Luigi SCOTTO, Shi Xian DENG, Rosa PURGATORIO, Jole FIORITO
  • HISTONE ACETYLTRANSFERASE ACTIVATORS AND USES THEREOF
    Publication number: 20170182054
    Abstract: The invention provides compounds and compositions comprising compounds that modulate histone acyl transferase (HAT). The invention further provides methods for treating neurodegenerative disorders, conditions associated with accumulated amyloid-beta peptide deposits, Tau protein levels, and/or accumulations of alpha-synuclein as well as cancer by administering a compound that modulates HAT to a subject.
    Type: Application
    Filed: March 30, 2015
    Publication date: June 29, 2017
    Inventors: Ottavio ARANCIO, Shixian DENG, Donald W. LANDRY, Jole FIORITO, Rosa PURGATORIO, Owen Anthony O'CONNOR, Jennifer Effie AMENGUAL