Abstract: A dual axis bioreactor system wherein a bioreactor vessel is mounted at its longitudinal axis to a horizontal axle with the bioreactor vessel thereby being rotatable about its longitudinal axis. The horizontal axle is rotatably mounted to a vertical shaft with the vertical shaft rotating the horizontal axle in a horizontal plane. A gear system limits the rotation of the bioreactor vessel to one rotation about its longitudinal axis for each revolution of the bioreactor vessel about the vertical shaft. A flexible, multilumen conduit is affixed to the base of the bioreactor vessel at the longitudinal axis to provide fluid communication with the bioreactor vessel. The rotation rate of the vertical shaft is carefully controlled to reduce any centrifugation effects upon the contents in the bioreactor vessel while providing mixing therein.

Abstract: An automatic hematocrit reader wherein a sample of blood in a microhematocrit capillary tube is banded with a standing wave from an ultrasonic transducer. A light source and photocell combination is used to determine the relative thicknesses of the bands of red blood cells and the bands of plasma. The hematocrit of the sample of blood is electronically calculated from this data. A calibration strip is included so that the device is calibrated each time the hematocrit is determined. The device includes a mechanical interlock/eject system for the microhematocrit capillary tube and is specifically configured so that the operator does not handle or even touch the microhematocrit capillary tube.

Abstract: Methods and apparatus for controlling the movement of materials having different physical properties when one of the materials is a fluid. The invention does not rely on flocculation, sedimentation, centrifugation, the buoyancy of the materials, or any other gravity dependent characteristic, in order to achieve its desired results. The methods of the present invention provide that a first acoustic wave is propagated through a vessel containing the materials. A second acoustic wave, at a frequency different than the first acoustic wave, is also propagated through the vessel so that the two acoustic waves are superimposed upon each other. The superimposition of the two waves creates a beat frequency wave. The beat frequency wave comprises pressure gradients dividing regions of maximum and minimum pressure. The pressure gradients and the regions of maximum and minimum pressure move through space and time at a group velocity.

Abstract: This invention relates to an electronic level apparatus wherein a hollow torus is rotatably mounted in the level. A body of ferromagnetic fluid creates a horizontal reference and is sensed to provide an audible signal when a predetermined angular orientation is detected by the sensor.

Abstract: This invention is a semiautomatic hematocrit reader apparatus and method. A microhematocrit capillary tube is positioned under a movable cursor which is then moved along the length of the microhematocrit capillary tube. A switch is depressed to make a data entry at predetermined points along the length of a blood/plasma sample in the microhematocrit capillary tube. The relative distances travelled across the packed cell volume versus the plasma is electronically calculated and displayed automatically.

Abstract: This invention is a dual axis, continuous flow centrifuge apparatus and method. A centrifuge head rotates in a vertical orientation about a first axis which, in turn, is rotated in a horizontal plane about a second axis. The rotation of the centrifuge head is matched to the rotation of the second axis to cancel out any net rotation of flexible conduits attached to the centrifuge head. The nonrotating coupling of the conduits permits continuous flow through the centrifuge head in the absence of seals. An angled centrifuge chamber inside the centrifuge head provides a more rapid separation of the components in the liquid passing through the centrifuge head. The path of travel of a particle in a centrifuge chamber inside the centrifuge head follows a generally cycloidal path thereby undergoing a pulsatile centrifugal force component.

Abstract: This invention is an ultrasound apparatus for determining hematocrit. A sample of blood in a microhematocrit capillary tube is acoustically coupled to an ultrasound transducer which creates a standing wave in the blood sample. Red blood cells in the blood sample are packed in bands that correspond to the nodes of the standing wave. The thickness of the bands as a function of the thickness of the remaining plasma is an indication of the hematocrit of the blood sample.

Abstract: Methods and apparatus for maintaining urinary continence in normally incontinent individuals. The present invention involves the non-surgical implantation of a bolus of ferromagnetic material into the bladder. The bolus of ferromagnetic material may comprise a biocompatible membrane, containing a ferromagnetic material. The bolus will normally rest at the juncture between the bladder and the urethra and will prevent the flow of urine from the bladder into the urethra. Essentially, the bolus serves as a seal between the urethra and the bladder. When it is desired to void the bladder, the ferromagnetic bolus is moved out of the intersection between the bladder and the urethra by positioning a magnet along the external surface of the person's body and manipulating the magnet until the desired movement of the bolus is accomplished. Movement of the magnet is sufficient to displace the bolus such that flow may be initiated from the bladder into the urethra.

Abstract: This invention relates to the ultrasound enhancement of sedimentation of particulates in a particulate-bearing fluid medium while the fluid medium is undergoing centrifugation. The ultrasound energy forms standing waves in the fluid and cause particulates in the fluid, whether solids, liquids, or gases, to agglomerate in bands. The bands approximate either the nodes or antinodes of the standing wave, depending on the density of the particulate relative to the fluid. The banded or agglomerated particulate enhances the rate of sedimentation as well as the reverse flow of suspernatent by removing particulate which would otherwise impede this flow.

Abstract: Methods and apparatus for controlling the movement of materials having different physical properties when one of the materials is a fluid. The invention does not rely on flocculation, sedimentation, centrifugation, the buoyancy of the materials, or any other gravity dependent characteristic, in order to achieve its desired results. The methods of the present invention provide that a first acoustic wave is progpagated through a vessel containing the materials. A second acoustic wave, at a frequency different than the first acoustic wave, is also propagated through the vessel so that the two acoustic waves are superimposed upon each other. The superimposition of the two waves creates a beat frequency wave. The beat frequency wave comprises pressure gradients dividing regions of maximum and minimum pressure. The pressure gradients and the regions of maximum and minimum pressure move through space and time at a group velocity.

Abstract: A hand-held centrifuge apparatus for sedimenting a fluid suspension in a sample tube, the sample tube being subjected to centrifugation at an acute angle to the axis of rotation. An electronic circuit activates an electric motor for a preselected time period as a function of voltage supplied by a battery to the motor to provide a predetermined degree of centrifugation to the sample. A voltage tester periodically tests the voltage in the circuit to assure that adequate voltage is being supplied by the battery. A deactivation circuit is actuated if inadequate voltage is sensed and a disabling circuit disables the electronic circuit until adequate voltage is again available. The disabling circuit is masked during acceleration to preclude deactivating the circuit when the motor is in acceleration.

Abstract: An artificial sphincter apparatus and method, the artificial sphincter including a pair of parallel, coaxially mounted rings with at least one ring rotatable relative to the other. Optionally the rings are capable of being split open at their circumference and reclosed for mounting about a living tissue conduit for which surgical severing is not recommended. A plurality of circumferentially mounted tie members extend between the rings and are drawn laterally toward the center of the sphincter, narrowing a passageway therethrough, upon relative rotation between the rings. This action is capable of gently constricting a living tissue conduit within the passageway using a combination of rotational and circumferentially localized discrete radially compressive forces to control the flow of biological materials within the living tissue conduit. A cell impervious thin flexible tubular membrane envelopes the sphincter to isolate it from the immediate environment.