Patents by Inventor Owen O. Witto

Owen O. Witto has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Chimeric messenger RNA detection methods
    Patent number: 5057410
    Abstract: The invention provides highly sensitive methods for detecting specific sequences contained in chimeric mRNA. The mRNA sequences are reverse transcribed into complementary DNA (cDNA), amplified by the Polymerase Chain Reaction, and detected by hybridization with a labeled sequence specific oligonucleotide probe. The method is particularly valuable for the detection of chimeric mRNAs experessed by activated oncogenes that result from aberrant genetic rearragements such as chromosomal translocations.
    Type: Grant
    Filed: August 5, 1988
    Date of Patent: October 15, 1991
    Assignee: Cetus Corporation
    Inventors: Ernest S. Kawasaki, Francis P. McCormick, Owen O. Witto