Abstract: A microfluidic chip and holder assembly includes a base having a seat and at least a first fluid channel that extends through the base. The first fluid channel has an inlet that is spaced from the seat for connection to a fluid supply and an outlet that is in the seat. A microfluidic chip is received by the seat, and the microfluidic chip has a fluid pathway. A cover is mounted over the microfluidic chip to sandwich the microfluidic chip between the cover and the base. The cover bears against the microfluidic chip to force the microfluidic chip to bear against the base and form a sealed connection between the outlet of the fluid channel and the fluid pathway of the microfluidic chip.

Abstract: A holder for a microfluidic chip includes a base having an outward facing surface, a seat defined in the outward facing surface for receiving a microfluidic chip, and a first circular wall extending around the seat and having a first screw thread. A cover is mountable to the base over the seat for retaining the microfluidic chip on the seat. The cover has a window and a second circular wall extending around the window. The second circular wall has a second screw thread. The second screw thread is engageable with the first screw thread to screw the cover to the base with the window overlying the seat.