Patents by Inventor Owen Shea
Owen Shea has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20230338577Abstract: Provided herein are compounds of Formula (I), and salts thereof, wherein each instance of RL is independently optionally substituted C6-C40 alkenyl. Further provided are compositions comprising a compound of Formula (I) and an agent. Further provided are methods and kits using the compositions for delivering an agent to a subject or cell and for treating and/or preventing a range of diseases. Further provided are methods of preparing compounds of Formula (I) and precursors thereof.Type: ApplicationFiled: May 2, 2023Publication date: October 26, 2023Applicant: Massachusetts Institute of TechnologyInventors: Daniel Griffith Anderson, Joseph R. Dorkin, Owen Shea Fenton, Kevin John Kauffman, Rebecca L. McClellan
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Patent number: 11679165Abstract: Provided herein are compounds of Formula (I), and salts thereof, wherein each instance of RL is independently optionally substituted C6-C40 alkenyl. Further provided are compositions comprising a compound of Formula (I) and an agent. Further provided are methods and kits using the compositions for delivering an agent to a subject or cell and for treating and/or preventing a range of diseases. Further provided are methods of preparing compounds of Formula (I) and precursors thereof.Type: GrantFiled: May 20, 2020Date of Patent: June 20, 2023Assignee: Massachusetts Institute of TechnologyInventors: Daniel Griffith Anderson, Joseph R. Dorkin, Owen Shea Fenton, Kevin John Kauffman, Rebecca L. McClellan
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Patent number: 11491228Abstract: Provided herein are polymers of Formula (I), and pharmaceutically acceptable salts, co-crystals, tautomers, stereoisomers, and isotopically labeled derivatives thereof, compositions, and formulations thereof. The polymers described herein are biocompatible, non-toxic, water compatible, and operationally simple to formulate. Also provided are methods and kits involving the polymers described herein (e.g., methods of using polymers described herein for delivering agents (e.g., for therapeutic, diagnostic, prophylactic, imaging, ophthalmic, intraoperative, or cosmetic use) to a subject, cell, tissue, or biological sample, as part of materials (e.g., biodegradable materials, biocompatible materials, wound dressing (e.g., bandages), drug depots, coatings), or as scaffolds for tissue engineering. Provided are methods for synthesizing the polymers described herein, and polymers described herein synthesized by the synthetic methods described herein.Type: GrantFiled: July 3, 2019Date of Patent: November 8, 2022Assignee: Massachusetts Institute of TechnologyInventors: Robert S. Langer, Owen Shea Fenton, Jason Andresen, Marion Paolini
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Publication number: 20210349272Abstract: An optical transceiver may include a circuit board, lasers, and a PLC including optical multiplexers and demultiplexers. The PLC may be coupled to fiber optic lines at a forward edge of the PLC, with a rear edge of the PLC receiving light for transmission generated by the lasers. Light received at the forward edge of the PLC may be demultiplexed into data channels and routed to a top surface of the PLC for optoelectronic conversion by photodetectors. In some embodiments each data channel is routed into a corresponding plurality of waveguides, with each of the corresponding plurality of waveguides providing light to the same photodetector. In some embodiments at least some receive side electronic circuitry, other than photodetectors, is stacked on top of the PLC.Type: ApplicationFiled: December 17, 2020Publication date: November 11, 2021Inventors: Bardia Pezeshki, Hindrik Bulthuis, Ramsey Selim, Andrew Grant, Lucas Soldano, Owen Shea, Josef Wendland, Jamie Stokes, Suresh Rangarajan, Josh Oen, Ron Zhang, Rob Kalman, Drew Lundsten
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Publication number: 20200386956Abstract: An optical transceiver may include a circuit board, lasers, and a PLC including optical multiplexers and demultiplexers. The PLC may be coupled to fiber optic lines at a forward edge of the PLC, with a rear edge of the PLC receiving light for transmission generated by the lasers. Light received at the forward edge of the PLC may be demultiplexed into data channels and routed to a top surface of the PLC for optoelectronic conversion by photodetectors. In some embodiments each data channel is routed into a corresponding plurality of waveguides, with each of the corresponding plurality of waveguides providing light to the same photodetector. In some embodiments at least some receive side electronic circuitry, other than photodetectors, is stacked on top of the PLC.Type: ApplicationFiled: December 20, 2019Publication date: December 10, 2020Inventors: Bardia Pezeshki, Hendrick Bulthuis, Ramsey Selim, Andrew Grant, Lucas Soldano, Owen Shea, Josef Wendland, Jamie Stokes, Suresh Rangarajan, Josh Oen, Ron Zhang, Rob Kalman, Drew Lundsten
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Publication number: 20200353099Abstract: Provided herein are compounds of Formula (I), and salts thereof, wherein each instance of RL is independently optionally substituted C6-C40 alkenyl. Further provided are compositions comprising a compound of Formula (I) and an agent. Further provided are methods and kits using the compositions for delivering an agent to a subject or cell and for treating and/or preventing a range of diseases. Further provided are methods of preparing compounds of Formula (I) and precursors thereof.Type: ApplicationFiled: May 20, 2020Publication date: November 12, 2020Applicant: Massachusetts Institute of TechnologyInventors: Daniel Griffith Anderson, Joseph R. Dorkin, Owen Shea Fenton, Kevin John Kauffman, Rebecca L. McClellan
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Patent number: 10695444Abstract: Provided herein are compounds of Formula (I), and salts thereof, wherein each instance of RL is independently optionally substituted C6-C40 alkenyl. Further provided are compositions comprising a compound of Formula (I) and an agent. Further provided are methods and kits using the compositions for delivering an agent to a subject or cell and for treating and/or preventing a range of diseases. Further provided are methods of preparing compounds of Formula (I) and precursors thereof.Type: GrantFiled: February 6, 2019Date of Patent: June 30, 2020Assignee: Massachusetts Institute of TechnologyInventors: Daniel Griffith Anderson, Joseph R. Dorkin, Owen Shea Fenton, Kevin John Kauffman, Rebecca L. McClellan
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Publication number: 20200009256Abstract: Provided herein are polymers of Formula (I), and pharmaceutically acceptable salts, co-crystals, tautomers, stereoisomers, and isotopically labeled derivatives thereof, compositions, and formulations thereof. The polymers described herein are biocompatible, non-toxic, water compatible, and operationally simple to formulate. Also provided are methods and kits involving the polymers described herein (e.g., methods of using polymers described herein for delivering agents (e.g., for therapeutic, diagnostic, prophylactic, imaging, ophthalmic, intraoperative, or cosmetic use) to a subject, cell, tissue, or biological sample, as part of materials (e.g., biodegradable materials, biocompatible materials, wound dressing (e.g., bandages), drug depots, coatings), or as scaffolds for tissue engineering. Provided are methods for synthesizing the polymers described herein, and polymers described herein synthesized by the synthetic methods described herein.Type: ApplicationFiled: July 3, 2019Publication date: January 9, 2020Applicant: Massachusetts Institute of TechnologyInventors: Robert S. Langer, Owen Shea Fenton, Jason Andresen, Marion Paolini
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Publication number: 20190278035Abstract: An optical transceiver may include a circuit board, lasers, and a PLC including optical multiplexers and demultiplexers. The PLC may be coupled to fiber optic lines at a forward edge of the PLC, with a rear edge of the PLC receiving light for transmission generated by the lasers. Light received at the forward edge of the PLC may be demultiplexed into data channels and routed to a top surface of the PLC for optoelectronic conversion by photodetectors. In some embodiments each data channel is routed into a corresponding plurality of waveguides, with each of the corresponding plurality of waveguides providing light to the same photodetector. In some embodiments at least some receive side electronic circuitry, other than photodetectors, is stacked on top of the PLC.Type: ApplicationFiled: March 11, 2019Publication date: September 12, 2019Inventors: Bardia Pezeshki, Hendrick Bulthuis, Ramsey Selim, Andrew Grant, Lucas Soldano, Owen Shea, Josef Wendland, Jamie Stokes, Suresh Rangarajan, Josh Oen, Ron Zhang, Rob Kalman, Drew Lundsten
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Publication number: 20190240349Abstract: Provided herein are compounds of Formula (I), and salts thereof, wherein each instance of RL is independently optionally substituted C6-C40 alkenyl. Further provided are compositions comprising a compound of Formula (I) and an agent. Further provided are methods and kits using the compositions for delivering an agent to a subject or cell and for treating and/or preventing a range of diseases. Further provided are methods of preparing compounds of Formula (I) and precursors thereof.Type: ApplicationFiled: February 6, 2019Publication date: August 8, 2019Inventors: Daniel Griffith Anderson, Joseph R. Dorkin, Owen Shea Fenton, Kevin John Kauffman, Rebecca L. McClellan
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Patent number: 10201618Abstract: Provided herein are compounds of Formula (I), and salts thereof, wherein each instance of RL is independently optionally substituted C6-C40 alkenyl. Further provided are compositions comprising a compound of Formula (I) and an agent. Further provided are methods and kits using the compositions for delivering an agent to a subject or cell and for treating and/or preventing a range of diseases. Further provided are methods of preparing compounds of Formula (I) and precursors thereof.Type: GrantFiled: June 17, 2016Date of Patent: February 12, 2019Assignee: Massachusetts Institute of TechnologyInventors: Daniel Griffith Anderson, Joseph R. Dorkin, Owen Shea Fenton, Kevin John Kauffman, Rebecca L. McClellan
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Patent number: 10054739Abstract: An optical transceiver may include pairs of lasers, each laser of a particular pair generating light at the same wavelength and each pair of lasers generating light at different wavelengths. The light from the lasers may be demultiplexed onto a pair of outputs, with each output receiving light from different lasers of each pair of lasers.Type: GrantFiled: September 18, 2017Date of Patent: August 21, 2018Assignee: Kaiam Corp.Inventors: Owen Shea, Bardia Pezeshki, Andrew Grant, Jamie Stokes, Henk Bulthuis, Dinh Ton, Ramsey Selim
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Publication number: 20180081117Abstract: An optical transceiver may include pairs of lasers, each laser of a particular pair generating light at the same wavelength and each pair of lasers generating light at different wavelengths. The light from the lasers may be demultiplexed onto a pair of outputs, with each output receiving light from different lasers of each pair of lasers.Type: ApplicationFiled: September 18, 2017Publication date: March 22, 2018Inventors: Owen Shea, Bardia Pezeshki, Andrew Grant, Jamie Stokes, Henk Bulthuis, Dinh Ton, Ramsey Selim
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Patent number: 9840479Abstract: The present disclosure provides polyamine-fatty acid derived lipidoids (e.g., compounds of Formula (I) or (II)) and methods of preparing the lipidoids. A described lipidoid includes R—C(?O)—O— moieties (where R is a lipid moiety), which may be hydrolyzed into non-toxic fatty acids. Also provided are compositions including a described lipidoid and an agent (e.g., polynucleotide, small molecule, peptide, or protein). The present disclosure also provides methods, kits, and uses that involve the lipidoids or compositions for delivering an agent to a subject, tissue, or cell and/or for treating and/or preventing a range of diseases, such as genetic diseases, proliferative diseases, hematological diseases, neurological diseases, immunological diseases, gastrointestinal diseases, respiratory diseases, painful conditions, psychiatric disorders, and metabolic disorders.Type: GrantFiled: July 1, 2015Date of Patent: December 12, 2017Assignee: Massachusetts Institute of TechnologyInventors: Owen Shea Fenton, Joseph Robert Dorkin, Daniel Griffith Anderson, Rebecca L. McClellan
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Publication number: 20160367686Abstract: Provided herein are compounds of Formula (I), and salts thereof, wherein each instance of RL is independently optionally substituted C6-C40 alkenyl. Further provided are compositions comprising a compound of Formula (I) and an agent. Further provided are methods and kits using the compositions for delivering an agent to a subject or cell and for treating and/or preventing a range of diseases. Further provided are methods of preparing compounds of Formula (I) and precursors thereof.Type: ApplicationFiled: June 17, 2016Publication date: December 22, 2016Inventors: Daniel Griffith Anderson, Joseph R. Dorkin, Owen Shea Fenton, Kevin John Kauffman, Rebecca L. McClellan
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Publication number: 20160002178Abstract: The present disclosure provides polyamine-fatty acid derived lipidoids (e.g., compounds of Formula (I) or (II)) and methods of preparing the lipidoids. A described lipidoid includes R—C(?O)—O— moieties (where R is a lipid moiety), which may be hydrolyzed into non-toxic fatty acids. Also provided are compositions including a described lipidoid and an agent (e.g., polynucleotide, small molecule, peptide, or protein). The present disclosure also provides methods, kits, and uses that involve the lipidoids or compositions for delivering an agent to a subject, tissue, or cell and/or for treating and/or preventing a range of diseases, such as genetic diseases, proliferative diseases, hematological diseases, neurological diseases, immunological diseases, gastrointestinal diseases, respiratory diseases, painful conditions, psychiatric disorders, and metabolic disorders.Type: ApplicationFiled: July 1, 2015Publication date: January 7, 2016Applicant: Massachusetts Institute of TechnologyInventors: Owen Shea Fenton, Joseph Robert Dorkin, Daniel Griffith Anderson, Rebecca L. McClellan
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Patent number: 4025435Abstract: Paint filtering apparatus for supporting a filter medium, such as foraminous cloth or the like, above a paint pail. The apparatus includes an impervious plate larger than the mouth of the paint pail and legs for supporting the plate above a surface on which the paint pail can be rested. The plate defines a circular opening having a diameter smaller than the diameter of the mouth of the paint pail. A cylindric rim that is sized to fit within the hole in the plate and having protrusions fastened thereto for bearing on the plate to retain the rim in place. Above the protrusions the rim defines an annular groove, and there is a strap that can be placed in the groove to retain the filter medium within the groove throughout the extent thereof. The rim is smaller than the diameter of a paint bucket so that a paint bucket can be rested on the rim in an inverted position to afford draining of the same without continuing attention.Type: GrantFiled: July 25, 1975Date of Patent: May 24, 1977Inventor: Dennis Owen Shea