Patents by Inventor Owen Witte

Owen Witte has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Positron emission tomography probe to monitor selected sugar metabolism in vivo
    Patent number: 9592309
    Abstract: The invention disclosed herein discloses selected ribose isomers that are useful as PET probes (e.g. [18F]-2-fluoro-2-deoxy-arabinose). These PET probes are useful, for example, in methods designed to monitor physiological processes including ribose metabolism and/or to selectively observe certain tissue/organs in vivo. The invention disclosed herein further provides methods for making and using such probes.
    Type: Grant
    Filed: May 9, 2013
    Date of Patent: March 14, 2017
    Assignee: The Regents of the University of California
    Inventors: Owen Witte, Peter M. Clark, Blanca Graciela Flores Castillo, Michael E. Jung, Nikolai M. Evdokimov
  • POSITRON EMISSION TOMOGRAPHY PROBE TO MONITOR SELECTED SUGAR METABOLISM IN VIVO
    Publication number: 20150133777
    Abstract: The invention disclosed herein discloses selected ribose isomers that are useful as PET probes (e.g. [18F]-2-fluoro-2-deoxy-arabinose). These PET probes are useful, for example, in methods designed to monitor physiological processes including ribose metabolism and/or to selectively observe certain tissue/organs in vivo. The invention disclosed herein further provides methods for making and using such probes.
    Type: Application
    Filed: May 9, 2013
    Publication date: May 14, 2015
    Inventors: Owen Witte, Peter M. Clark, Blanca Graciela Flores Castillo, Michael E. Jung, Nikolai M. Evdokimov
  • Capture agents and related methods and systems for detecting and/or sorting targets
    Patent number: 8394590
    Abstract: Polynucleotide-encoded capture agents for target detection and in particular modular polynucleotide-capture agents comprising a target binding component, a scaffold component and an encoding component formed by standardized molecular units that can be coupled and decoupled in a controlled fashion, and related compositions methods and systems.
    Type: Grant
    Filed: October 8, 2010
    Date of Patent: March 12, 2013
    Assignees: California Institute of Technology, University of California
    Inventors: Gabriel A. Kwong, Caius G. Radu, Owen Witte, James R. Heath, Antoni Ribas
  • CAPTURE AGENTS AND RELATED METHODS AND SYSTEMS FOR DETECTING AND/OR SORTING TARGETS
    Publication number: 20110166034
    Abstract: Polynucleotide-encoded capture agents for target detection and in particular modular polynucleotide-capture agents comprising a target binding component, a scaffold component and an encoding component formed by standardized molecular units that can be coupled and decoupled in a controlled fashion, and related compositions methods and systems.
    Type: Application
    Filed: October 8, 2010
    Publication date: July 7, 2011
    Inventors: Gabriel A. Kwong, Caius G. Radu, Owen Witte, James R. Heath, Antoni Ribas
  • PSCA antibodies and hybridomas producing them
    Publication number: 20080318254
    Abstract: The invention provides a novel prostate cell-surface antigen, designated Prostate Stem Cell Antigen (PSCA), which is widely over-expressed across all stages of prostate cancer, including high grade prostatic intraepithelial neoplasia (PIN), androgen-dependent and androgen-independent prostate tumors.
    Type: Application
    Filed: January 29, 2004
    Publication date: December 25, 2008
    Applicant: The Regents of the University of California
    Inventors: Robert Reiter, Owen Witte
  • PSCA prostate stem cell antigen and uses thereof
    Publication number: 20080318253
    Abstract: The invention provides a novel prostate cell-surface antigen, designated Prostate Stem Cell Antigen (PSCA), which is widely over-expressed across all stages of prostate cancer, including high grade prostatic intraepithelial neoplasia (PIN), androgen-dependent and androgen-independent prostate tumors.
    Type: Application
    Filed: August 21, 2002
    Publication date: December 25, 2008
    Inventors: Robert Reiter, Owen Witte, Douglas Saffran, Aya Jakobovits
  • MOUSE MODELS OF HUMAN PROSTATE CANCER
    Publication number: 20070006331
    Abstract: The present invention provides an immune deficient mouse having a human prostate xenograft of locally advanced or metastatic prostate cancer and uses thereof.
    Type: Application
    Filed: September 12, 2006
    Publication date: January 4, 2007
    Applicant: The Regents of the University of California
    Inventors: Charles Sawyers, Karen Klein, Owen Witte, Robert Reiter
  • PSCA: prostate stem cell antigen and uses thereof
    Publication number: 20050152909
    Abstract: The invention provides a novel prostate cell-surface antigen, designated Prostate Stem Cell Antigen (PSCA), which is widely over-expressed across all stages of prostate cancer, including high grade prostatic intraepithelial neoplasia (PIN), androgen-dependent and androgen-independent prostate tumors.
    Type: Application
    Filed: November 23, 2004
    Publication date: July 14, 2005
    Applicant: The Regents of the University of California
    Inventors: Robert Reiter, Owen Witte, Douglas Saffran, Aya Jakobovits
  • PSCA: prostate stem cell antigen and uses thereof
    Publication number: 20050059099
    Abstract: The invention provides a novel prostate cell-surface antigen, designated Prostate Stem Cell Antigen (PSCA), which is widely over-expressed across all stages of prostate cancer, including high grade prostatic intraepithelial neoplasia (PIN), androgen-dependent and androgen-independent prostate tumors.
    Type: Application
    Filed: January 29, 2004
    Publication date: March 17, 2005
    Applicants: The Regents of the University of California, Agensys, Inc.
    Inventors: Robert Reiter, Owen Witte, Douglas Saffran, Aya Jakobovits
  • PSCA antibodies and hybridomas producing them
    Publication number: 20050026229
    Abstract: The invention provides a novel prostate cell-surface antigen, designated Prostate Stem Cell Antigen (PSCA), which is widely over-expressed across all stages of prostate cancer, including high grade prostatic intraepithelial neoplasia (PIN), androgen-dependent and androgen-independent prostate tumors.
    Type: Application
    Filed: January 29, 2004
    Publication date: February 3, 2005
    Applicant: The Regents of the University of California
    Inventors: Robert Reiter, Owen Witte
  • PSCA: prostate stem cell antigen and uses thereof
    Publication number: 20050003465
    Abstract: The invention provides a novel prostate cell-surface antigen, designated Prostate Stem Cell Antigen (PSCA), which is widely over-expressed across all stages of prostate cancer, including high grade prostatic intraepithelial neoplasia (PIN), androgen-dependent and androgen-independent prostate tumors.
    Type: Application
    Filed: January 29, 2004
    Publication date: January 6, 2005
    Applicants: The Regents of the University of California, Agensys, Inc.
    Inventors: Robert Reiter, Owen Witte, Douglas Saffran, Aya Jakobovits
  • Hematopoietic restricted tyrosine kinase (BPK)
    Patent number: 5550054
    Abstract: Novel hematopoietic-restricted tyrosine kinases are provided, where the tyrosine kinases provide for autophosphorylation and transphosphorylation. Modulation of the activity of the subject compositions can be used to restrict growth and differentiation, to correct genetic deficiencies, and to elucidate the activation pathway involved with the subject tyrosine kinases. In addition, the tyrosine kinases may be used in a variety of assays as a label or in the production of the phosphorylated peptides.
    Type: Grant
    Filed: February 21, 1995
    Date of Patent: August 27, 1996
    Assignee: The Regents of the University of California
    Inventors: Owen Witte, Satoshi Tsukada, Douglas Saffran, David Rawlings