Abstract: A lamp assembly operable to project light in a forward direction along an optical axis includes at least one light emitting device, a first light collector and a second light collector. The at least one light emitting device includes a light emitting surface. The first light collector is disposed on a first side of the light emitting device and defines a first axis. The first light collector is symmetrically disposed about the first axis. The second light collector is disposed on a second side of the light emitting device opposite the first side and defines a second axis. The second axis is substantially aligned with the first axis. The second light collector is symmetrically disposed about the second axis. The first and second axes are tangential to the light emitting surface.

Abstract: A lamp assembly operable to project light in a forward direction along an optical axis includes at least one light emitting device, a first light collector and a second light collector. The at least one light emitting device includes a light emitting surface. The first light collector is disposed on a first side of the light emitting device and defines a first axis. The first light collector is symmetrically disposed about the first axis. The second light collector is disposed on a second side of the light emitting device opposite the first side and defines a second axis. The second axis is substantially aligned with the first axis. The second light collector is symmetrically disposed about the second axis. The first and second axes are tangential to the light emitting surface.

Abstract: The optics system is a lamp assembly which produces the desired beam pattern by using a reflector, a lens, a retainer lens, and an LED as a light source. The lamp assembly has three main components (the reflector, the lens, and the retainer lens) that maintain proper alignment between the light source and the reflector, the lens, and the retainer lens. The optical system collects substantially 100% of the light from the light source while effectively shaping the beam pattern using both cylindrical and revolved reflector elements. The lens has a saddle-shape which is used with the surface of a revolution to eliminate any “dogbone” light pattern shape. The use of a reflective element forms the foreground of the beam pattern.

Abstract: Genome-wide association studies (GWAS) was recently used to identify SNPs in a genomic region on chromosome 4 that associate with serum urate levels and gout. The present disclosure shows that human ATP-binding cassette, subfamily G, 2 (ABCG2), encoded by the ABCG2 gene contained in this region, is a hitherto unknown urate efflux transporter. The present disclosure further shows that native ABCG2 is located in the brush border membrane of kidney proximal tubule cells, where it mediates renal urate secretion. Introduction of the mutation Q141K encoded by the common SNP rs2231142 by site-directed mutagenesis resulted in reduced urate transport rates compared to wild-type ABCG2. Data from a population-based study of 14,783 individuals support rs2231142 as the causal variant in the region and show highly significant associations with urate levels and gout.

Abstract: The optics system is a lamp assembly which produces the desired beam pattern by using a reflector, a lens, a retainer lens, and an LED as a light source. The lamp assembly has three main components (the reflector, the lens, and the retainer lens) that maintain proper alignment between the light source and the reflector, the lens, and the retainer lens. The optical system collects substantially 100% of the light from the light source while effectively shaping the beam pattern using both cylindrical and revolved reflector elements. The lens has a saddle-shape which is used with the surface of a revolution to eliminate any “dogbone” light pattern shape. The use of a reflective element forms the foreground of the beam pattern.

Abstract: Genome-wide association studies (GWAS) was recently used to identify SNPs in a genomic region on chromosome 4 that associate with serum urate levels and gout. The present disclosure shows that human ATP-binding cassette, subfamily G, 2 (ABCG2), encoded by the ABCG2 gene contained in this region, is a hitherto unknown urate efflux transporter. The present disclosure further shows that native ABCG2 is located in the brush border membrane of kidney proximal tubule cells, where it mediates renal urate secretion. Introduction of the mutation Q141K encoded by the common SNP rs2231142 by site-directed mutagenesis resulted in reduced urate transport rates compared to wild-type ABCG2. Data from a population-based study of 14,783 individuals support rs2231142 as the causal variant in the region and show highly significant associations with urate levels and gout.

Abstract: A modular semiconductor light source assembly includes a semiconductor light source, such as a light emitting diode, which is mounted on a substrate which supplies electricity to the light source and which assists in removing waste heat therefrom. Substantially all of the light emitted by the LED is transferred to a lens by a light pipe, the cross section of the light pipe increasing from the light source to the lens and the lens having a general D-shape such that the light pattern formed by the lens is constrained in a first direction orthogonal to a second direction. The assembly can be combined with other similar assemblies or other light sources in a light fixture to produce a desired overall beam pattern such as a automobile headlamp low beam or high beam pattern.

Abstract: A headlamp fixture and a control system for controlling a vehicular lighting system to produce particular lighting patterns required under different regulatory regimes is disclosed. The headlamps employ semiconductor light sources to create the desired patterns and can include at least two inclined light source elements which are alternately illuminated to produce required side illumination or can include single light source elements which can be rotated clockwise and counterclockwise to produce the required side illumination. The lighting system can employ an output from a GPS receiver to determine the country or region in which the vehicle is being driven to automatically configure the operation of lighting system components, such as the side illumination of the headlamps and/or the activation and deactivation of daytime running lights, to meet the regulatory requirements of the country or region.

Abstract: An automotive lighting system employing semiconductor light sources includes LED light sources (52) which are mounted to an edge of a heat pipe (44) such that emitted light from the LED light sources travels toward a reflector (32) at the back of the housing (24) of the system, where it is reflected and/or focused forward through the lens (40) of the system. The heat pipe is thermally connected to a heat sink (35) which extends outside of the housing and which operates to remove heat from the LED light sources. The thickness of the heat pipe is significantly less than the size of the reflector, so that only a small amount of reflected light from the LED light sources is obscured.

Abstract: The present invention is a lighting arrangement having at least one light source, light at least two light pipes for receiving light from the light source, and a lens having two or more sections. The lens is configured to receive light from at least one of the at least two light pipes, wherein each one of the sections projects light in a desired isomeric beam pattern.

Abstract: A light engine (20) to provide light from a plurality of semiconductor light sources (40) in an automotive lighting system, such as a headlamp, includes a substrate (24) upon which the semiconductor light sources are mounted. The semiconductor light sources are spaced from one another on the substrate for cooling purposes. The substrate also preferably includes at least one layer (48) of heat transfer material which assists in transferring waste heat from the semiconductor light sources to a heat sink or other cooling means. The light engine (20) further includes a transfer device (28) comprising a bundle of fiber optic cables (60), one cable for each semiconductor light source (40), and each cable has a receiving end (32) which is located adjacent a respect one semiconductor light source (40) and an emitter end (36) which is located in close proximity to the emitter end of each other cable emitter end.

Abstract: A headlamp fixture and a control system for controlling a vehicular lighting system to produce particular lighting patterns required under different regulatory regimes is disclosed. The headlamps employ semiconductor light sources to create the desired patterns and can include at least two inclined light source elements which are alternately illuminated to produce required side illumination or can include single light source elements which can be rotated clockwise and counterclockwise to produce the required side illumination. The lighting system can employ an output from a GPS receiver to determine the country or region in which the vehicle is being driven to automatically configure the operation of lighting system components, such as the side illumination of the headlamps and/or the activation and deactivation of daytime running lights, to meet the regulatory requirements of the country or region.

Abstract: A vehicle headlamp includes a reflector, a source and a lens. The headlamp is configured so that light from the source reflects from the reflector and is output from the headlamp through the lens. Concave reflector sections are formed by dividing the reflector. Each reflector section has a primary focal point and primary axis. The primary focal points of the reflector sections are coincident and the primary axes of the reflector sections are angled with respect to one another.

Abstract: A vehicle headlamp includes a reflector, a source and a lens. The headlamp is configured so that light from the source reflects from the reflector and is output from the headlamp through the lens. Concave reflector sections are formed by dividing the reflector. Each reflector section has a primary focal point and primary axis. The primary focal points of the reflector sections are coincident and the primary axes of the reflector sections are angled with respect to one another.

Abstract: A distributed lighting system has a light source and a set of optical conduits. Input ends of the set of optical conduits may be placed in close proximity to the light source to increase the efficiency with which light is transmitted from the light source to the optical conduits. The efficiency also may be increased by placing a light collector between the light source and the input ends of the optical conduits.