Patents by Inventor Oyvind Molberg

Oyvind Molberg has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Prolyl endopeptidase mediated destruction of T cell epitopes in whole gluten
    Patent number: 7563864
    Abstract: Celiac Sprue and/or dermatitis herpetiformis are treated by interfering with HLA binding of immunogenic gluten peptides. The antigenicity of gluten oligopeptides and the ill effects caused by an immune response thereto are decreased by administration of an HLA-binding peptide inhibitor. Such inhibitors are analogs of immunogenic gluten peptides and (i) retain the ability to bind tightly to HLA molecules; (ii) retain the proteolytic stability of these peptides; but (iii) are unable to activate disease-specific T cells.
    Type: Grant
    Filed: April 26, 2005
    Date of Patent: July 21, 2009
    Assignees: Celiac Sprue Research Foundation, Universitetet I Oslo
    Inventors: Thomas Marti, Øyvind Molberg, Ludvig M. Sollid
  • Prolyl endopeptidase mediated destruction of T cell epitopes in whole gluten
    Publication number: 20060286601
    Abstract: Celiac Sprue and/or dermatitis herpetiformis are treated by interfering with HLA binding of immunogenic gluten peptides. The antigenicity of gluten oligopeptides and the ill effects caused by an immune response thereto are decreased by administration of an HLA-binding peptide inhibitor. Such inhibitors are analogs of immunogenic gluten peptides and (i) retain the ability to bind tightly to HLA molecules; (ii) retain the proteolytic stability of these peptides; but (iii) are unable to activate disease-specific T cells.
    Type: Application
    Filed: April 26, 2005
    Publication date: December 21, 2006
    Inventors: Thomas Marti, Oyvind Molberg, Ludvig Sollid