Abstract: Embodiments of the present disclosure relate generally to systems and methods for sorting and analyzing cells and, more particularly, to systems and methods for sorting and analyzing cells using magnetophoresis in a microfluidic platform. Some embodiments of a microfluidic device comprise an inlet for receiving a plurality of magnetically-labeled cells, a flow chamber, a magnet positioned alongside the flow chamber, and a plurality of bins having a sensor for detecting the magnetically-labeled cells. In some embodiments, the magnetic flux of the magnet causes the magnetically-labeled cells to be deflected to a particular bin. The sensors of each bin can be used to calculate the surface antigen expression and/or size of the cells within a sample of magnetically-labeled cells.

Abstract: Embodiments of the present disclosure relate generally to systems and methods for sorting and analyzing cells and, more particularly, to systems and methods for sorting and analyzing cells using magnetophoresis in a microfluidic platform. Some embodiments of a microfluidic device comprise an inlet for receiving a plurality of magnetically-labeled cells, a flow chamber, a magnet positioned alongside the flow chamber, and a plurality of bins having a sensor for detecting the magnetically-labeled cells. In some embodiments, the magnetic flux of the magnet causes the magnetically-labeled cells to be deflected to a particular bin. The sensors of each bin can be used to calculate the surface antigen expression and/or size of the cells within a sample of magnetically-labeled cells.