Patents by Inventor Ozlem GOKER-ALPAN

Ozlem GOKER-ALPAN has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • INHIBITION OF CASPASE PATHWAY AS A TREATMENT FOR LYSOSOMAL STORAGE DISORDERS
    Publication number: 20230404972
    Abstract: Disclosed is a method of preventing, treating or reducing a lysosomal storage disorder (LSD) or a symptom thereof in a subject in need thereof comprising administering a therapeutically effective amount of caspase inhibitor to the subject. The therapeutically effective amount of caspase inhibitor may be a medicament or a composition for preventing, treating or reducing a lysosomal storage disorder (LSD) or a symptom thereof in a subject comprising a caspase inhibitor, and optionally a pharmaceutically acceptable carrier. One preferred caspase inhibitor is the pan caspase inhibitor Emricasan.
    Type: Application
    Filed: November 24, 2021
    Publication date: December 21, 2023
    Applicant: Lysosomal and Rare Disorders Research and Treatment Center, Inc.
    Inventors: Renuka Pudi LIMGALA, Ozlem GOKER-ALPAN
  • METHODS AND COMPOSITIONS FOR TREATING LYSOSOMAL STORAGE DISORDERS: AMBROXOL AS TREATMENT AGENT FOR MUCOPOLYSACCHARIDOSES III (SANFILIPPO SYNDROME)
    Publication number: 20220133653
    Abstract: Methods for treating MPS III diseases are disclosed. The methods involve administering a therapeutically effective amount of a composition comprising ambroxol to a subject with the disease. Also disclosed are pharmaceuticals suitable for treating MPS III diseases.
    Type: Application
    Filed: February 14, 2020
    Publication date: May 5, 2022
    Applicants: Lysosomal and Rare Disorders Research and Treatment Center, Inc., Rare Cures Corporation
    Inventors: Ozlem GOKER-ALPAN, Margarita M. IVANOVA
  • ALPHA-SYNUCLEIN IN PERIPHERAL BLOOD MONONUCLEAR CELLS AS BIOMARKER FOR SYNUCLEINOPATHY
    Publication number: 20190170771
    Abstract: Disclosed is a rapid, non-invasive and highly specific and sensitive diagnostic assay for the identification of individuals with synucleinopathy and for measuring synucleinopathy progression or status. Test kits for diagnosis of an individual suspected of having synucleinopathy are also disclosed.
    Type: Application
    Filed: July 28, 2017
    Publication date: June 6, 2019
    Inventors: Renuka Pudi LIMGALA, Ozlem GOKER-ALPAN