Abstract: The present disclosure provides monoclonal antibodies that bind to endothelial monocyte activating polypeptide II and methods of treatment using the same.

Abstract: Systems, methods, and devices of the various embodiments enable graph based routing of containers and adjustments of container routing based on one or more current material handling system state. The various embodiments enable examination and evaluation of the material handling systems using graphs to find an optimal route from a starting node in the material handling system to an ending node in the material handling system. In an embodiment, the graph may be a directed graph of edges and nodes of a material handling system. In an embodiment, the directed graph may include edge weights and the edge weights may be used to determine the optimal route for the container. In an embodiment, the edge weights may be updated as events occur in the material handling system which may result in dynamic routing of containers through the material handling system.

Abstract: Systems, methods, and devices of the various embodiments enable graph based routing of containers and adjustments of container routing based on one or more current material handling system state. The various embodiments enable examination and evaluation of the material handling systems using graphs to find an optimal route from a starting node in the material handling system to an ending node in the material handling system. In an embodiment, the graph may be a directed graph of edges and nodes of a material handling system. In an embodiment, the directed graph may include edge weights and the edge weights may be used to determine the optimal route for the container. In an embodiment, the edge weights may be updated as events occur in the material handling system which may result in dynamic routing of containers through the material handling system.

Abstract: A flow meter is disclosed with a hollow blocking rotor. The flow meter includes a housing that has a cavity with an inlet and an outlet. The flow meter also includes a pair of displacement rotors with a blocking rotor disposed between the displacement rotors. The blocking rotor includes a pair of convex walls and a pair of concave walls. The blocking rotor further includes a shaft coupled to the pair of concave walls. Each concave wall is disposed between and coupled to a pair of opposing convex walls. The concave walls provide clearance for rotation of the displacement rotors when the displacement rotors sweep along the concave walls. The hollow configuration of the blocking rotor reduces the impedance of the flow meter.

Abstract: A flow meter is disclosed with a hollow blocking rotor. The flow meter includes a housing that has a cavity with an inlet and an outlet. The flow meter also includes a pair of displacement rotors with a blocking rotor disposed between the displacement rotors. The blocking rotor includes a pair of convex walls and a pair of concave walls. The blocking rotor further includes a shaft coupled to the pair of concave walls. Each concave wall is disposed between and coupled to a pair of opposing convex walls. The concave walls provide clearance for rotation of the displacement rotors when the displacement rotors sweep along the concave walls. The hollow configuration of the blocking rotor reduces the impedance of the flow meter.

Abstract: Provided herein are novel heteroaryl compounds, compositions comprising the compounds, and methods of treatment or prevention comprising administration of the compounds. The compounds are effective in the targeting of cells defective in the von Hippel-Lindau gene and in inducing autophagic cell death. The methods are directed to treating or preventing diseases such as cancer, and in particular cancers resulting from von Hippel-Lindau disease. The compounds of the invention may be administered in combination with another therapeutic agent.

Abstract: The boat engine cooling system provides cooling of the engine of a boat or other nautical vehicle through both chemical coolant, such as an antifreeze solution, and environmental water; i.e., the water the vehicle is passing through. In use, heated engine coolant is expelled by the engine and passes through a coolant inlet port formed through a hollow tank, where it is transported through a coolant pipe to the engine. Further, water from the environment (i.e., the lake, ocean or other body of water the vehicle is passing through) is injected into a cooling reservoir in the hollow tank through a water inlet port. The engine coolant passing through a central portion of the coolant pipe is cooled by the water in the cooling reservoir prior to circulating back through the engine.

Abstract: A method and system for storing and evolving hydrogen employ chemical compounds that can be hydrogenated to store hydrogen and dehydrogenated to evolve hydrogen. A catalyst lowers the energy required for storing and evolving hydrogen. The method and system can provide hydrogen for devices that consume hydrogen as fuel.

Abstract: A system and method for arbitrating among memory requests. According to a preferred embodiment, the system comprises a global memory and a plurality of datapaths. Each datapath comprises a datapath processor for executing instructions of an instruction sequence and for providing a plurality of memory request signal types in accordance with the instructions, wherein the plurality of memory request signal types comprises instruction memory request signals, scalar memory request signals, first-in and first-out memory request signals, statistical decoder memory request signals, and block transfer memory request signals. Each datapath also comprises local memory, a global port for transferring data between the local memory and the global memory, and a dual port comprising first and second local ports for transferring data between the local memory and the datapath processor, wherein the first and second local ports permit simultaneous transfer of data between the local memory and the datapath processor.

Abstract: A method and apparatus for processing data. According to a preferred embodiment, the apparatus comprises a plurality of datapaths, each datapath comprising datapath processor, and a statistical decoder input channel device. The statistical decoder input channel device prefetches variable length encoded data from a variable length encoded data source in response to a request by a program running on a datapath processor of a datapath of the plurality of datapaths. The statistical decoder input channel device comprises a statistical decoder processor and memory for decoding the variable length encoded data to provide fixed length decoded data, and a transmission output channel for transmitting the fixed length decoded data to the datapath.

Abstract: A system and method for processing data. According to a preferred embodiment, the system comprises a global memory and a plurality of datapaths. Each datapath comprises a datapath processor for executing instructions of an instruction sequence and for providing a plurality of memory request signal types in accordance with the instructions, local memory, a global port for transferring data between the local memory and the global memory, and a dual port comprising first and second local ports for transferring data between the local memory and the datapath processor, wherein the first and second local ports permit simultaneous transfer of data between the local memory and the datapath processor.

Abstract: A data processing system having execution units for executing instruction sequences determines at least two conditionals in accordance with the instructions and sets respective flags according to the determined conditionals. These flags are stored and later retrieved sequentially and the execution unit executes selected instructions of the instruction sequence according to the sequentially retrieved mask flags. These masked flags may be stored sequentially in a stack for sequential retrieval at a later time.

Abstract: The use of specific primers and a probe in a reverse transcriptase-polymerase chain reaction provides a method for specifically identifying bovine respiratory syncytial virus in cattle.

Abstract: A single-instruction multiple-data video signal processor employs a dual-ported local memory architecture in each local memory including a dedicated port for transfers between the local memory and a global memory. A block transfer controller, in combination with the dedicated port, permit each access to the global memory by a datapath processor to be overlapped with its instruction processing, thus usually avoiding stalling of the video signal processor.

Abstract: The use of E. suis specific primers in PCR with DNA from swine blood increases the sensitivity of current DNA hybridization protocols for determining whether swine are infected with E. suis prior to the development of any clinical symptoms. The present invention provides these E. suis primers and a method to use these primers in a PCR protocol to provide a highly sensitive diagnostic assay for early signs of an E. suis infection.

Abstract: A data bus having a given size (e.g., 32 bits) provides for transfer of information between various logic and memory elements within, or among, one or more integrated circuits. Certain of the information transfers require the full information path, while others use only a portion (e.g., 8 or 16 bit transfers). To expedite the transfers of the smaller size words, a given word is replicated to fill up the full data base. This avoids the necessity of specifying the exact location of the smaller word on the data bus.

Abstract: A fire extinguisher includes a pressure vessel containing an extinguishing agent and pressurized gas and a valve remotely operated by a manual control at the outlet end of the delivery hose for controlling the discharge of the extinguishing agent from the pressure vessel to the delivery hose. This discharge control valve is opened and closed by a pneumatic cylinder operated by pressurized gas from a valve pneumatically operated by a manually actuated valve mounted near the outlet end of the delivery hose.

Abstract: A fire extinguishing system includes a container of extinguishing agent and a valve for controlling the discharge of the extinguishing agent. The discharge control valve is opened and closed by a pneumatic cylinder operated by pressurized gas through a solenoid-actuated directional control valve. The solenoid of the directional control valve is coupled with a pneumatic timing relay actuated by a temperature sensor. With this arrangement, a pre-determined amount of extinghishing agent is discharged from the container and delivered to the hazard area and then the discharge shut-off. The discharge cycle is repeated, if necessary, until the fire is extinguished. The system is then automatically reset and ready to deliver further extinguishing agent on demand. The system also includes manual or automatic means for purging the delivery line downstream of the discharge control valve.