Publication number: 20200131249
Abstract: The invention relates to proteins containing any of the sequences according to general formula (Ih): X1CRX2X3X4X5??(Ih) where X1 is F, Y, L, P, Q, M, V, W, A, T and X2 is A, G, S, T and X3 is V, A, I, L, M, D, H, S and X4 is K, I, Q, R, H, S, F, M, N, L, V and X5 is R, V, I, K, M, Q, E, F, L, N, Y, D, S, H. and its salts, esters and pharmaceutically acceptable prodrugs. The invention further relates to pharmaceutical preparations and kits containing said proteins, to screening procedures using said proteins. The proteins of the invention are useful in the treatment or prevention of diseases that can be treated by inhibiting the complement system.
Type:
Application
Filed:
January 4, 2018
Publication date:
April 30, 2020
Applicant:
EVOLVERITAS KFT.
Inventors:
Peter GAL, Gabor PAL, David SZAKACS