Abstract: The present disclosure pertains to a system and method for monitoring lung disease in a patient that is based on information that is derivable from home therapy devices including a ventilation therapy device and an oxygen saturation monitor such as a pulse oximeter. The measured parameters are used to model shunt fraction and a volume of dead space. Based on changes in gas exchange and results of a nitrogen washout test, a change in gas exchange impairment in the patient is observed and is then used to determine progression of a disease, identify a cause of the impairment, and/or to guide treatment of the patient.

Abstract: Provided are concepts for generating an indicator of chronic obstructive pulmonary disease (COPD) in a subject. In particular, an elasticated bag suitable for inflation is utilised, such that a change in a measurable characteristic of the elasticated during exhalation of the subject is detected. The change in the measurable characteristic may be analyzed so as to generate an indicator of COPD. Thus, this indicator may be used by a skilled professional in deciding whether to further investigate the possible presence of COPD.

Abstract: A method for controlling a ventilator to provide variable volume (VV) with average volume assured pressure support (AVAPS), including: producing a VV target volume using a VV distribution function; producing a volume error Verror that is the difference between the VV target volume and a measured volume of the previous breath; scaling the volume error Verror; producing a VV target difference as the difference between VV target volume and the VV target volume of the previous breath; producing a modified volume error by adding the VV target difference to the scaled volume error Verror; producing a delta pressure support ?PS based upon the modified volume error and a dynamic compliance; and producing a current pressure support value based upon the delta pressure support ?PS and the pressure support value of the previous breath.

Abstract: The present disclosure pertains to a system and method for monitoring lung disease in a patient that is based on information that is derivable from home therapy devices including a ventilation therapy device and an oxygen saturation monitor such as a pulse oximeter. The measured parameters are used to model shunt fraction and a volume of dead space. Based on changes in gas exchange and results of a nitrogen washout test, a change in gas exchange impairment in the patient is observed and is then used to determine progression of a disease, identify a cause of the impairment, and/or to guide treatment of the patient.

Abstract: A system and method for determining a patient condition includes receiving sensor information over an observation period, generating one or more metrics based on the sensor information, comparing the one or metrics to reference information to determine deviation information, and generating a risk score indicating a probability that a patient is experiencing an COPD-related event based on the deviation information. The sensor information is received from one or more sensors at predetermined locations of a patient location.