Patents by Inventor Pablo Antonio Martin-Gago

Pablo Antonio Martin-Gago has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Benzene disulfonamide for the treatment of cancer
    Patent number: 10913710
    Abstract: The present invention relates to novel substituted benzene disulfonamides, as well as pharmaceutical compositions containing at least one of these substituted benzene disulfonamides together with at least one pharmaceutically acceptable carrier, excipient and/or diluent. Said substituted benzene disulfonamides are binding to the prenyl binding pocket of PDE6? and therefore, are useful for the prophylaxis and treatment of cancer by inhibition of the binding of PDE6? to farnesylated Ras proteins and thereby, inhibition of oncogenic Ras signaling in cells.
    Type: Grant
    Filed: January 11, 2018
    Date of Patent: February 9, 2021
    Assignee: Max-Planck-Gesellschaft zur Forderung der Wissenschaften e.V
    Inventors: Herbert Waldmann, Pablo Antonio Martin-Gago, Sandip Murarka, Christian Klein, Philippe Bastiaens, Alfred Wittinghofer, Eyad Kalawy Fansa
  • BENZENE DISULFONAMIDE FOR THE TREATMENT OF CANCER
    Publication number: 20190359563
    Abstract: The present invention relates to novel substituted benzene disulfonamides, as well as pharmaceutical compositions containing at least one of these substituted benzene disulfonamides together with at least one pharmaceutically acceptable carrier, excipient and/or diluent. Said substituted benzene disulfonamides are binding to the prenyl binding pocket of PDE6? and therefore, are useful for the prophylaxis and treatment of cancer by inhibition of the binding of PDE6? to farnesylated Ras proteins and thereby, inhibition of oncogenic Ras signaling in cells.
    Type: Application
    Filed: January 11, 2018
    Publication date: November 28, 2019
    Inventors: Herbert Waldmann, Pablo Antonio Martin-Gago, Sandip Murarka, Christian Klein, Philippe Bastiaens, Alfred Wittinghofer