Abstract: An instrument for the manipulation of the light wavefront, and a method for the manipulation of the light wavefront. The instrument for the manipulation of the light wavefront comprises: two or more active light modulation areas, and an optical system that determines an optical path between the active light modulation areas, which conjugates the planes (2, 6; 9, 12) of the active light modulation areas, the optical system comprising at least one mirror (4; 11) and at least one lens (3, 5; 10), wherein the active light modulation areas have a phase modulation depth of equal to or less than ? radians.

Abstract: Method to design manufacture an intraocular lens, comprising an optical part and haptics part, in which the optical part comprises an anterior surface with negative refractive power and a posterior surface with positive refractive power, in which in order to determine the refractive power D of the anterior surface of the optical part and the refractive power D? of the posterior surface of the optical part the following steps are performed: a plurality of light rays are provided over the normal eye, both on the optical axis (1001) and forming different angles (714, 715, 716) with respect to the optical axis (1001), for each light ray with its angle the axial length of the eye and the refractive power of the cornea are measured, determination of the shape of the retina (200) through a mathematical fit to an aspherical surface that contains the measured points, calculation of the arc length S that goes from the intersection of the optical axis with the retina (200) of the eye to the intersection of the light

Abstract: A lens for use in an intraocular lens system for treating age-related macular degeneration (AMD), the lens including an anterior surface, a posterior surface, and a plurality of haptics configured to align the anterior light-converging intraocular lens with an optical axis of the eye. The plurality of haptics may have a symmetrical design and comprising ciliary-sulcus-engaging surfaces configure to position the lens within in a ciliary sulcus of an eye. At least one of the anterior surface and the posterior surface may be rendered as aspherical surfaces selected to induce spherical aberration while minimizing optical aberration and thereby provide for a continuum of retinal images to be focused at an area macula of a retina of the eye between two retinal eccentricities.

Abstract: An intraocular lens system comprising a single lens comprising two optical surfaces selected to maintain image quality at the foveal centre whilst reducing image aberration at preferred retinal locus locations outside of the fovea region.

Abstract: An intraocular lens system comprising at least one intraocular lens having an anterior surface and a posterior surface, wherein at least one surface of the lens is aspherical to provide for a continuum of retinal images to be focused at the retina in an area between two retinal eccentricities. The system may include an anterior light-converging intraocular lens 16 for positioning within the eye, the anterior lens having an anterior surface and a posterior surface; and a posterior light-diverging intraocular lens 17 for positioning within the eye posterior to the anterior lens, the posterior lens having an anterior surface and a posterior surface; wherein one or both surfaces of the anterior lens and/or one or both surfaces of the posterior lens are aspherical.

Abstract: Intraocular lens and methods for optimization of depth of focus and the image quality in the periphery of the visual field.

Abstract: A Light Adjustable Lens (LAL) comprises a central region, centered on a central axis, having a position-dependent central optical power, and a peripheral annulus, centered on an annulus axis and surrounding the central region, having a position-dependent peripheral optical power; wherein the central optical power is at least 0.5 diopters different from an average of the peripheral optical power, and the central axis is laterally shifted relative to the annulus axis. A method of adjusting the LAL comprises implanting a LAL; applying a first illumination to the LAL with a first illumination pattern to induce a position-dependent peripheral optical power in at least a peripheral annulus, centered on an annulus axis; determining a central region and a corresponding central axis of the LAL; and applying a second illumination to the LAL with a second illumination pattern to induce a position-dependent central optical power in the central region of the LAL.

Abstract: An intraocular lens system comprising a single lens comprising two optical surfaces selected to maintain image quality at the foveal centre whilst reducing image aberration at preferred retinal locus locations outside of the fovea region.

Abstract: A Light Adjustable Lens (LAL) comprises a central region, centered on a central axis, having a position-dependent central optical power, and a peripheral annulus, centered on an annulus axis and surrounding the central region, having a position-dependent peripheral optical power; wherein the central optical power is at least 0.5 diopters different from an average of the peripheral optical power, and the central axis is laterally shifted relative to the annulus axis. A method of adjusting the LAL comprises implanting a LAL; applying a first illumination to the LAL with a first illumination pattern to induce a position-dependent peripheral optical power in at least a peripheral annulus, centered on an annulus axis; determining a central region and a corresponding central axis of the LAL; and applying a second illumination to the LAL with a second illumination pattern to induce a position-dependent central optical power in the central region of the LAL.

Abstract: Method to design manufacture an intraocular lens, comprising an optical part and haptics part, in which the optical part comprises an anterior surface with negative refractive power and a posterior surface with positive refractive power, in which in order to determine the refractive power D of the anterior surface of the optical part and the refractive power D? of the posterior surface of the optical part the following steps are performed: a plurality of light rays are provided over the normal eye, both on the optical axis (1001) and forming different angles (714, 715, 716) with respect to the optical axis (1001), for each light ray with its angle the axial length of the eye and the refractive power of the cornea are measured, determination of the shape of the retina (200) through a mathematical fit to an aspherical surface that contains the measured points, calculation of the arc length S that goes from the intersection of the optical axis with the retina (200) of the eye to the intersection of the light

Abstract: An intraocular lens system comprising a single lens comprising two optical surfaces selected to maintain image quality at the foveal centre whilst reducing image aberration at preferred retinal locus locations outside of the fovea region.

Abstract: A Light Adjustable Lens (LAL) comprises a central region, centered on a central axis, having a position-dependent central optical power, and a peripheral annulus, centered on an annulus axis and surrounding the central region, having a position-dependent peripheral optical power; wherein the central optical power is at least 0.5 diopters different from an average of the peripheral optical power, and the central axis is laterally shifted relative to the annulus axis. A method of adjusting the LAL comprises implanting a LAL; applying a first illumination to the LAL with a first illumination pattern to induce a position-dependent peripheral optical power in at least a peripheral annulus, centered on an annulus axis; determining a central region and a corresponding central axis of the LAL; and applying a second illumination to the LAL with a second illumination pattern to induce a position-dependent central optical power in the central region of the LAL.

Abstract: Optical instrument for measuring the density of macular pigment in the eye and associated method. The instrument includes: a light source (500), several lenses L1, L2, L3 between the light source and the eye, a diaphragm D1 conjugate to the eye pupil plane, a photodetector (520), a mirror M that directs the light exiting the eye to the photodetector (520), a diaphragm D2 conjugated to the pupil plane of the eye, at least one lens L4 between diaphragm D2 and the photodetector (520), the light source (500) has a central part (501) and a peripheral part (502), the light source (500) being modulated at four different frequencies corresponding to green light in the central part and in the peripheral part, blue light in the central part and in the peripheral part, projecting the light from the light source (500) on the fundus of the eye.

Abstract: An intraocular lens system comprising at least one intraocular lens having an anterior surface and a posterior surface, wherein at least one surface of the lens is aspherical to provide for a continuum of retinal images to be focused at the retina in an area between two retinal eccentricities. The system may include an anterior light-converging intraocular lens 16 for positioning within the eye, the anterior lens having an anterior surface and a posterior surface; and a posterior light-diverging intraocular lens 17 for positioning within the eye posterior to the anterior lens, the posterior lens having an anterior surface and a posterior surface; wherein one or both surfaces of the anterior lens and/or one or both surfaces of the posterior lens are aspherical.

Abstract: An intraocular lens system comprising at least one intraocular lens having an anterior surface and a posterior surface, wherein at least one surface of the lens is aspherical to provide for a continuum of retinal images to be focused at the retina in an area between two retinal eccentricities. The system may include an anterior light-converging intraocular lens 16 for positioning within the eye, the anterior lens having an anterior surface and a posterior surface; and a posterior light-diverging intraocular lens 17 for positioning within the eye posterior to the anterior lens, the posterior lens having an anterior surface and a posterior surface; wherein one or both surfaces of the anterior lens and/or one or both surfaces of the posterior lens are aspherical.

Abstract: Optoelectronic binocular instrument for the automatic correction of presbyopia and method for the binocular correction of the presbyopia. The instrument has two optoelectronic lenses (103, 110; 203, 204) and a capturing subsystem for taking images of the eye. By means of the pupil tracking, which performs the processing of the eye's images, the system determines the distance where the subject is looking at. The pupil tracking works at a very high speed, using a high-performance graphic processor and a highly parallelized algorithm for pupil tracking. The method consists of two phases. In the first one a calibration is accomplished, the subject is asked to look at targets at different distances and the size and position of the pupil is measured. In the second phase the correction is performed by the instrument, the system continuously captures and processes images to calculate the correction to apply and, finally, corrects the presbyopia by applying said correction.

Abstract: In general, the present invention relates to optical elements, which can be modified post-manufacture such that different versions of the element will have different optical properties. In particular, the present invention relates to lenses, such as intraocular lenses, which can be converted into aspheric lenses post-fabrication. Also, the present invention relates to a method for forming aspheric lenses post-fabrication.

Abstract: Intraocular tens and methods for optimization of depth of focus and the image quality in the periphery of the visual field.

Abstract: An intraocular lens system comprising a single lens comprising two optical surfaces selected to maintain image quality at the foveal centre whilst reducing image aberration at preferred retinal locus locations outside of the fovea region.

Abstract: A system for predicting optical power for an intraocular lens based upon measured biometric parameters in a patient's eye includes: a biometric reader capable of measuring one or more biometric parameters of the patient's eye and obtaining at least one value for at least one of the one or more biometric parameters, and further measuring a representation of a corneal topography of the patient's eye; a processor; and a computer readable medium coupled to the processor and having stored thereon a program that upon execution causes the processor to: receive the at least one value; obtain a corneal spherical aberration (SA) based upon the representation of the corneal topography; and calculate an optimized optical power to obtain a desired postoperative condition by applying the received at least one value and the obtained corneal spherical aberration to a modified regression.