Patents by Inventor Pablo DOMÍNGUEZ DE MARÍA

Pablo DOMÍNGUEZ DE MARÍA has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Fusion proteins comprising an aldolase enzyme joined to a maltose binding protein
    Patent number: 10683493
    Abstract: The present invention refers to an enzyme consisting of a fusion protein particularly useful as shown through-out the present invention for carrying out the carbon-carbon bond-forming reaction known as the aldol Reaction, preferably for carrying out an aldol reaction by using aldehydes as substrates and preferably pyruvate or a salt thereof, for producing hydroxyketoacids. Said enzyme is made by binding an aldolase to a maltose binding protein. The enzymes display full activity under “highly denaturing” substrate loadings (aldehydes, >1 M).
    Type: Grant
    Filed: May 17, 2017
    Date of Patent: June 16, 2020
    Assignees: CONSEJO SUPERIOR DE INVESTIGACIONES CIENTÍFICAS, TECHNICAL UNIVERSITY OF DARMSTADT, SUSTAINABLE MOMENTUM, S.L.
    Inventors: Pedro Clapés Saborit, Karel Hernández Sánchez, Jesús Joglar Tamargo, Jordi Bujons Vilás, Wolf-Dieter Fessner, Pablo Domínguez De María
  • FUSION PROTEINS COMPRISING AN ALDOLASE ENZYME JOINED TO A MALTOSE BINDING PROTEIN
    Publication number: 20190194638
    Abstract: The present invention refers to an enzyme consisting of a fusion protein particularly useful as shown through-out the present invention for carrying out the carbon-carbon bond-forming reaction known as the aldol Reaction, preferably for carrying out an aldol reaction by using aldehydes as substrates and preferably pyruvate or a salt thereof, for producing hydroxyketoacids. Said enzyme is made by binding an aldolase to a maltose binding protein. The enzymes display full activity under “highly denaturing” substrate loadings (aldehydes, >1 M).
    Type: Application
    Filed: May 17, 2017
    Publication date: June 27, 2019
    Inventors: Pedro CLAPÉS SABORIT, Karel HERNÁNDEZ SÁNCHEZ, Jesús JOGLAR TAMARGO, Jordi BUJONS VILÁS, Wolf-Dieter FESSNER, Pablo DOMÍNGUEZ DE MARÍA