Patents by Inventor Pablo Manuel Avilés Marín

Pablo Manuel Avilés Marín has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMBINATION THERAPY WITH AN ANTITUMOR ALKALOID
    Publication number: 20230404999
    Abstract: The present invention relates to the combination of PM01183 with several anticancer drugs, in particular other anticancer drugs selected from antitumor platinum coordination complexes, antimetabolites, mitotic inhibitors, anticancer antibiotics, topoisomerase I and/or II inhibitors, proteasome inhibitors, histone deacetylase inhibitors, nitrogen mustard alkylating agents, nitrosourea alkylating agents, nonclassical alkylating agents, estrogen antagonists, androgen antagonists, mTOR inhibitors, tyrosine kinase inhibitors, and other agents selected from aplidine, ET-743, PM02734 and PM00104, and the use of these combinations in the treatment of cancer.
    Type: Application
    Filed: January 11, 2023
    Publication date: December 21, 2023
    Inventors: Victoria MONEO OCAÑA, Gema SANTAMARÍA NÚÑEZ, Luis Francisco GARCÍA FERNÁNDEZ, Carlos María GALMARINI, María José GUILLÉN NAVARRO, Pablo Manuel AVILÉS MARÍN
  • Combination therapy with an antitumor alkaloid
    Patent number: 11590129
    Abstract: The present invention relates to the combination of PM01183 with several anticancer drugs, in particular other anticancer drugs selected from antitumor platinum coordination complexes, antimetabolites, mitotic inhibitors, anticancer antibiotics, topoisomerase I and/or II inhibitors, proteasome inhibitors, histone deacetylase inhibitors, nitrogen mustard alkylating agents, nitrosourea alkylating agents, nonclassical alkylating agents, estrogen antagonists, androgen antagonists, mTOR inhibitors, tyrosine kinase inhibitors, and other agents selected from aplidine, ET-743, PM02734 and PM00104, and the use of these combinations in the treatment of cancer.
    Type: Grant
    Filed: November 28, 2017
    Date of Patent: February 28, 2023
    Assignee: PHARMA MAR, S.A.
    Inventors: Victoria Moneo Ocaña, Gema Santamaría Núñez, Luis Francisco García Fernández, Carlos María Galmarini, María José Guillén Navarro, Pablo Manuel Avilés Marín
  • COMBINATION THERAPY WITH AN ANTITUMOR ALKALOID
    Publication number: 20180078551
    Abstract: The present invention relates to the combination of PM01183 with several anticancer drugs, in particular other anticancer drugs selected from antitumor platinum coordination complexes, antimetabolites, mitotic inhibitors, anticancer antibiotics, topoisomerase I and/or II inhibitors, proteasome inhibitors, histone deacetylase inhibitors, nitrogen mustard alkylating agents, nitrosourea alkylating agents, nonclassical alkylating agents, estrogen antagonists, androgen antagonists, mTOR inhibitors, tyrosine kinase inhibitors, and other agents selected from aplidine, ET-743, PM02734 and PM00104, and the use of these combinations in the treatment of cancer.
    Type: Application
    Filed: November 28, 2017
    Publication date: March 22, 2018
    Inventors: Victoria MONEO OCAÑA, Gema SANTAMARÍA NÚÑEZ, Luis Francisco GARCÍA FERNÁNDEZ, Carlos María GALMARINI, María José GUILLÉN NAVARRO, Pablo Manuel AVILÉS MARÍN
  • COMBINATION THERAPY WITH AN ANTITUMOR ALKALOID
    Publication number: 20180078550
    Abstract: The present invention relates to the combination of PM01183 with several anticancer drugs, in particular other anticancer drugs selected from antitumor platinum coordination complexes, antimetabolites, mitotic inhibitors, anticancer antibiotics, topoisomerase I and/or II inhibitors, proteasome inhibitors, histone deacetylase inhibitors, nitrogen mustard alkylating agents, nitrosourea alkylating agents, nonclassical alkylating agents, estrogen antagonists, androgen antagonists, mTOR inhibitors, tyrosine kinase inhibitors, and other agents selected from aplidine, ET-743, PM02734 and PM00104, and the use of these combinations in the treatment of cancer.
    Type: Application
    Filed: November 28, 2017
    Publication date: March 22, 2018
    Inventors: Victoria MONEO OCAÑA, Gema SANTAMARÍA NÚÑEZ, Luis Francisco GARCÍA FERNÁNDEZ, Carlos María GALMARINI, María José GUILLÉN NAVARRO, Pablo Manuel AVILÉS MARÍN
  • COMBINATION THERAPY WITH AN ANTITUMOR ALKALOID
    Publication number: 20180008602
    Abstract: The present invention relates to the combination of PM01183 with several anticancer drugs, in particular other anticancer drugs selected from antitumor platinum coordination complexes, antimetabolites, mitotic inhibitors, anticancer antibiotics, topoisomerase I and/or II inhibitors, proteasome inhibitors, histone deacetylase inhibitors, nitrogen mustard alkylating agents, nitrosourea alkylating agents, nonclassical alkylating agents, estrogen antagonists, androgen antagonists, mTOR inhibitors, tyrosine kinase inhibitors, and other agents selected from aplidine, ET-743, PM02734 and PM00104, and the use of these combinations in the treatment of cancer.
    Type: Application
    Filed: September 21, 2017
    Publication date: January 11, 2018
    Inventors: Victoria MONEO OCAÑA, Gema SANTAMARÍA NÚÑEZ, Luis Francisco GARCÍA FERNÁNDEZ, Carlos María GALMARINI, María José GUILLÉN NAVARRO, Pablo Manuel AVILÉS MARÍN
  • Combination Therapy with an Antitumor Alkaloid
    Publication number: 20130266666
    Abstract: The present invention relates to the combination of PM01183 with several anticancer drugs, in particular other anticancer drugs selected from antitumor platinum coordination complexes, antimetabolites, mitotic inhibitors, anticancer antibiotics, topoisomerase I and/or II inhibitors, proteasome inhibitors, histone deacetylase inhibitors, nitrogen mustard alkylating agents, nitrosourea alkylating agents, nonclassical alkylating agents, estrogen antagonists, androgen antagonists, mTOR inhibitors, tyrosine kinase inhibitors, and other agents selected from aplidine, ET-743, PM02734 and PM00104, and the use of these combinations in the treatment of cancer.
    Type: Application
    Filed: November 11, 2011
    Publication date: October 10, 2013
    Applicant: PHARMA MAR, S.A.
    Inventors: Victoria Moneo Ocaña, Gema Santamaría Núñez, Luis Francisco García Fernández, Carlos Maria Galmarini, María José Guillén Navarro, Pablo Manuel Avilés Marín
  • Multiple myeloma treatments
    Patent number: 8435992
    Abstract: Methods for treating cancer by using compound PM00104, in particular, for treating multiple myeloma are provided.
    Type: Grant
    Filed: May 18, 2009
    Date of Patent: May 7, 2013
    Assignee: Pharma Mar S.A.
    Inventors: Enrique Ocio, Atanasio Pandiella, Jesús San Miguel, Pablo Manuel Avilés Marín
  • Antitumoral treatments
    Patent number: 8258098
    Abstract: The present invention relates to combinations of aplidine or aplidine analogues with other titumoral agents, and the use of these combinations in the treatment of cancer, in particular in the treatment of lung cancer, breast cancer, colon cancer, prostate cancer, renal cancer, melanoma, multiple myeloma, leukemia and lymphoma.
    Type: Grant
    Filed: February 28, 2007
    Date of Patent: September 4, 2012
    Assignee: Pharma Mar, S.A.
    Inventors: Glynn Thomas Faircloth, Pablo Manuel Aviles Marin, Doreen LePage, Jesus San Miguel Izquierdo, Atanasio Pandiella
  • Multiple Myeloma Treatments
    Publication number: 20110076343
    Abstract: Methods for treating cancer by using compound PM00104, in particular, for treating multiple myeloma are provided.
    Type: Application
    Filed: May 18, 2009
    Publication date: March 31, 2011
    Applicant: Pharma Mar, S.A.
    Inventors: Enrique Ocio, Atanasio Pandiella, Jesús San Miguel, Pablo Manuel Avilés Marín
  • Combination Therapy with an Antitumor Alkaloid
    Publication number: 20110070232
    Abstract: The present invention relates to combinations of PM00104 with other anticancer drugs, and the use of these combinations in the treatment of cancer.
    Type: Application
    Filed: May 18, 2009
    Publication date: March 24, 2011
    Applicant: Pharma Mar, S.A.
    Inventors: Doreen LePage, Pablo Manuel Aviles Marin, Maria Jose Guillen Navarro
  • Anticancer Treatments
    Publication number: 20110009335
    Abstract: The present invention relates to combinations of aplidine with another anticancer drug selected from sorafenib, temsirolimus, and sunitinib, and the use of these combinations in the treatment of cancer.
    Type: Application
    Filed: March 6, 2009
    Publication date: January 13, 2011
    Inventors: Doreen LePage, Pablo Manuel Aviles Marin, Maria Jose Guillen
  • ANTITUMORAL TREATMENTS
    Publication number: 20090246168
    Abstract: The present invention relates to combinations of aplidine or aplidine analogues with other antitumoral agents, and the use of these combinations in the treatment of cancer, in particular in the treatment of lung cancer, breast cancer, colon cancer, prostate cancer, renal cancer, melanoma, multiple myeloma, leukemia and lymphoma.
    Type: Application
    Filed: February 28, 2007
    Publication date: October 1, 2009
    Applicant: PHARMA MAR, S.A.
    Inventors: Glynn Thomas Faircloth, Pablo Manuel Aviles Marin, Doreen LePage, Jesus San Miguel Izquierdo, Atanasio Pandiella