Abstract: Methods and apparatus for classifying or predicting the classes for samples based on gene expression are described. Also described are methods and apparatus for ascertaining or discovering new, previously unknown classes based on gene expression.

Abstract: Methods for predicting phenotypic classes of brain tumors, such as brain tumor type or treatment outcome, for brain tumor samples based on gene expression profiles are described.

Abstract: The present invention relates to methods and apparatus for grouping or clustering gene expression patterns from a plurality of genes. The invention utilizes a Self Organizing Map to cluster the gene expression patterns into groups that exhibit similar patterns. The clustering enables one to easily analyze gene expression data from potentially thousands of genes.

Abstract: Sets of genetic markers for specific tumor classes are described, as well as methods of identifying a biological sample based on these markers. Also described are diagnostic, prognostic, and therapeutic screening uses for these markers, as well as oligonucleotide arrays comprising these markers.

Abstract: An enterprise-wide web data mining system, computer program product, and method of operation thereof, that uses Internet based data sources, and which operates in an automated and cost effective manner. The enterprise web mining system comprises: a database coupled to a plurality of data sources, the database operable to store data collected from the data sources; a data mining engine coupled to the web server and the database, the data mining engine operable to generate a plurality of data mining models using the collected data; a server coupled to a network, the server operable to: receive a request for a prediction or recommendation over the network, generate a prediction or recommendation using the data mining models, and transmit the generated prediction or recommendation.

Abstract: Identification of MYC target genes whose expression is either induced or repressed by c-myc induction in human fibroblasts is disclosed. Also disclosed are methods of inducing or repressing expression of MYC target genes.