Patents by Inventor Padiyath Mohammed Akbarali

Padiyath Mohammed Akbarali has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Salts of Saxagliptin with organic acids
    Patent number: 9994523
    Abstract: The invention relates to organic salts of Saxagliptin and processes for their preparation.
    Type: Grant
    Filed: May 24, 2013
    Date of Patent: June 12, 2018
    Assignee: Apotex Inc.
    Inventors: Padiyath Mohammed Akbarali, Venkata Ramana Kintali, Shreenivasa Murthy H N, Prakash Bhaskar Shetty, Narendra Manjeshwar Mallya, Venkataramana Lachhi Reddy
  • Solid forms of Ivacaftor and processes for the preparation thereof
    Patent number: 9809551
    Abstract: Provided herein is a polymorphic form of Ivacaftor, namely APO-I, as well as processes for the preparation and pharmaceutical compositions of the same. Also, provided is a new solvate of Ivacaftor, processes for its preparation and use in the preparation of pure Ivacaftor.
    Type: Grant
    Filed: November 13, 2014
    Date of Patent: November 7, 2017
    Assignee: Apotex Inc.
    Inventors: Padiyath Mohammed Akbarali, Kintali Venkata Ramana, Heggadde Nanjunda Bhatta Shreenivasa Murthy, Sankaran Suresh Kumar, Ekkaluru Vijaya Bhaskar, Nechipadappu Sunil Kumar, Karad Manjunath
  • Bosutinib forms and preparation methods thereof
    Patent number: 9776970
    Abstract: The present subject matter relates to solvates and the amorphous form of bosutinib; the solvates namely being a propylene glycol solvate and an acetonitrile solvate. Also provided are processes for preparing the propylene glycol solvate, the amorphous form and the crystalline acetonitrile solvate of bosutinib; as well as compositions comprising said forms. Bosutinib is a 3-quinolinecarbonitrile kinase inhibitor and is indicated for the treatment of adult patients with chronic, accelerated, or blast phase Ph+ chronic myelogenous leukemia (CMS) with resistance or intolerance to prior therapy.
    Type: Grant
    Filed: February 20, 2015
    Date of Patent: October 3, 2017
    Assignee: Apotex Inc.
    Inventors: Padiyath Mohammed Akbarali, Venkata Ramana Kintali, Heggadde Nanjunda Bhatta Shreenivasa Murthy, Girisha Meenkere, Somanath Bhupal Venkata, Raja Ramesh Manda, Vishal Amrutlal Sodha, Abbulu Kante
  • Bosutinib Forms and Preparation Methods Thereof
    Publication number: 20170057923
    Abstract: The present subject matter relates to solvates and the amorphous form of bosutinib; the solvates namely being a propylene glycol solvate and an acetonitrile solvate. Also provided are processes for preparing the propylene glycol solvate, the amorphous form and the crystalline acetonitrile solvate of bosutinib; as well as compositions comprising said forms. Bosutinib is a 3-quinolinecarbonitrile kinase inhibitor and is indicated for the treatment of adult patients with chronic, accelerated, or blast phase Ph+ chronic myelogenous leukemia (CMS) with resistance or intolerance to prior therapy.
    Type: Application
    Filed: February 20, 2015
    Publication date: March 2, 2017
    Applicant: Apotex Inc.
    Inventors: Padiyath Mohammed Akbarali, Venkata Ramana Kintali, Heggadde Nanjunda Bhatta Shreenivasa Murthy, Girisha Meenkere, Somanath Bhupal Venkata, Raja Ramesh Manda, Vishal Amrutlal Sodha, Abbulu Kante
  • Solid Forms of Ivacaftor and Processes for the Preparation Thereof
    Publication number: 20160280654
    Abstract: Provided herein is a polymorphic form of Ivacaftor, namely APO-I, as well as processes for the preparation and pharmaceutical compositions of the same. Also, provided is a new solvate of Ivacaftor, processes for its preparation and use in the preparation of pure Ivacaftor.
    Type: Application
    Filed: November 13, 2014
    Publication date: September 29, 2016
    Inventors: Padiyath Mohammed Akbarali, Kintali Venkata Ramana, Heggadde Nanjunda Bhatta Shreenivasa Murthy, Sankaran Suresh Kumar, Ekkaluru Vijaya Bhaskar, Nechipadappu Sunil Kumar, Karad Manjunath
  • SALTS OF SAXAGLIPTIN WITH ORGANIC ACIDS
    Publication number: 20150353490
    Abstract: The invention relates to organic salts of Saxagliptin and processes for their preparation.
    Type: Application
    Filed: May 24, 2013
    Publication date: December 10, 2015
    Applicant: APOTEX INC.
    Inventors: Padiyath Mohammed AKBARALI, Venkata Ramana KINTALI, Shreenivasa Murthy H N, Prakash Bhaskar SHETTY, Narendra Manjeshwar MALLYA, Venkataramana Lachhi REDDY
  • Process for producing Ibuprofen sodium dihydrate
    Patent number: 7084299
    Abstract: Disclosed herein is a novel process for producing Sodium dihydrate salt of Ibuprofen of Formula (Structure I) by treating a salt of long chain carboxylic acid of Formula (Structure III) with Ibuprofen of Formula (Structure II) in the presence of an aqueous organic solvent.
    Type: Grant
    Filed: March 14, 2005
    Date of Patent: August 1, 2006
    Assignee: Strides Research and Specialty Chemicals Limited
    Inventors: Padiyath Mohammed Akbarali, Kuniyil Kulangara Vijaya Raj, Ramesh Sabu Gani, Sujatha Krishna, Sumangala Venkatrraman, Manjathur Mahalinga
  • Processes for producing triaryl phosphite
    Patent number: 6653494
    Abstract: A one pot process for the preparation of sterically hindered triaryl phosphite is provided. It is suitable for large scale commercial production with an advantage of having carried out the reaction at 0-5° C. in a shortest time of 1 hr using pyridine as Lewis base to remove HCl formed in the reaction; thus avoiding the usage of scrubber. The triaryl phosphite is of the formula P(OR)3 and is produced by reacting a di alkyl—substituted phenol of formula ROH with phosphorus trihalide in a presence of a Lewis base, wherein R represents an aryl compound of a formula C6H3RaRb, wherein Ra is tertiary alkyl, Rb is lower alkyl or tertiary alkyl. The process preferably comprises of mixing a stoichiometric amount of 2,4-dialkyl phenol with phosphorous trihalide in methylene chloride with different stoichiometric amounts of pyridine such as the molar equivalent, 10 mol %, 20 mol % and 50 mol % more than the amount of 2,4 dialkyl phenol. The reaction is preferably carried out at 0-5° C.
    Type: Grant
    Filed: August 2, 2002
    Date of Patent: November 25, 2003
    Assignee: Strides Inc.
    Inventors: Padiyath Mohammed Akbarali, Kuniyil Kulangara Vijay Raj, Karabasana T. Gouda, Ramachandran Radhakrishnan