Patents by Inventor Paivi Liesi

Paivi Liesi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Biologically active peptides and their use for repairing injured nerves
    Patent number: 7741436
    Abstract: The present invention relates to biologically active peptides derived from the neurite outgrowth-promoting domain of laminin-1, i.e. the ?1-chain of laminin-1. These peptides include the decapeptide RDIAEIIKDI (SEQ ID NO: 1) and the truncated peptides derived therefrom comprising the biologically active domain thereof, the tripeptide KDI. The invention is directed to the biologically active tripeptide motif KDI, and to its use in promoting regeneration of neuronal or non-neuronal tissues and, in specific, to its use in the treatment of spinal cord injuries.
    Type: Grant
    Filed: June 18, 2008
    Date of Patent: June 22, 2010
    Inventor: Päivi Liesi
  • Methods of inhibiting glutamate receptors by administering the tripeptide KDI
    Patent number: 7659255
    Abstract: The present invention relates to a method of using biologically active peptide compounds comprising the tri-peptide motif KDI derived from the neurite outgrowth-promoting domain of laminin-1 as inhibitors of ionotropic glutamate receptors. The peptide compounds are therefore useful in methods of treating disorders responsive to the blockade of these receptors, such as Alzheimer's disease, Parkinson's disease, ALS or stroke.
    Type: Grant
    Filed: May 12, 2005
    Date of Patent: February 9, 2010
    Inventor: Paivi Liesi
  • BIOLOGICALLY ACTIVE PEPTIDES AND THEIR USE FOR REPAIRING INJURED NERVES
    Publication number: 20080249021
    Abstract: The present invention relates to biologically active peptides derived from the neurite outgrowth-promoting domain of laminin-1, i.e. the ?1 -chain of laminin-1. These peptides include the decapeptide RDIAEIIKDI (SEQ ID NO:1) and the truncated peptides derived therefrom comprising the biologically active domain thereof, the tripeptide KDI. The invention is directed to the biologically active tripeptide motif KDI, and to its use in promoting regeneration of neuronal or non-neuronal tissues and, in specific, to its use in the treatment of spinal cord injuries.
    Type: Application
    Filed: June 18, 2008
    Publication date: October 9, 2008
    Inventor: Paivi LIESI
  • Biologically active peptides as glutamate receptor inhibitors
    Publication number: 20050288231
    Abstract: The present invention relates to biologically active peptides derived from the neurite outgrowth-promoting domain of luminin-1, i.e. the ?1-chain of laminin-1. These peptides include the decapeptide RDIAEIIKDI (SEQ ID NO: 1) and the truncated peptides derived therefrom comprising the biologically active domain thereof, the tripeptide KDI. The invention is directed to the biologically active tripeptide motifKDI, and to its use in promoting regeneration of neuronal or non-neuronal tissues and, in specific, to its use in the treatment of spinal cord injuries.
    Type: Application
    Filed: May 12, 2005
    Publication date: December 29, 2005
    Inventor: Paivi Liesi
  • Biologically active peptides and their use for repairing injured nerves
    Publication number: 20040266991
    Abstract: The present invention relates to biologically active peptides derived from the neurite outgrowth-promoting domain of laminin-1, i.e. the &ggr;1-chain of laminin-1. These peptides include the decapeptide RDIAEIIKDI and the truncated peptides derived therefrom comprising the biologically active domain thereof, the tripeptide KDI. The invention is directed to the biologically active tripeptide motif KDI, and to its use in promoting regeneration of neuronal or non-neuronal tissues and, in specific, to its use in the treatment of spinal cord injuries.
    Type: Application
    Filed: April 16, 2004
    Publication date: December 30, 2004
    Inventor: Paivi Liesi