Abstract: 2-phenoxy-, 2-phenylthio-, and 2-phenylamino-alkyl-2-oxazolines suitable for pharmaceutical use as hypolipemic and hypocholestric agents are disclosed.

Abstract: Novel 6-amino-5.alpha.,19-cycloandrostane derivatives of formula I and their pharmaceutically acceptable addition salts ##STR1## wherein X denotes any of the groups of the formula =CH(OR), =CO or =C=N-OR.sub.1,Y denotes any of the groups of the formula =CO, =CH(OR.sub.1), =C=N-OR.sub.1, =C(OR.sub.1)-C.tbd.CH or ##STR2## wherein R denotes a hydrogen atom, a C.sub.1-4 alkyl group or a C.sub.2-5 acyl group, andR.sub.1 denotes a hydrogen atom, a straight-chained or branched C.sub.1-5 alkyl group, a straight-chained or branched C.sub.1-5 hydroxyalkyl group, a C.sub.3-8 cycloalkyl group, an allyl group, or a benzyl group, andR.sub.3 has the same meaning as R.sub.2 but if R.sub.2 is a sec. or tert. alkyl group or an alicyclic group, then R.sub.3 can only be a hydrogen atom; and if R.sub.2 is a benzyl group then R.sub.3 can only be a hydrogen atom or a primary alkyl group, furtherR.sub.2 and R.sub.3 may denote together with the adjcacent nitrogen atom a piperidine, a morpholine, or an N-methylpiperazine group.

Abstract: This invention relates to compounds of the formula ##SPC1##WhereinR.sup.1 is hydrogen or an alkyl group having 1-4 carbon atoms;R.sup.2 but R.sup.3 are hydrogen and if both R.sup.4 and R.sup.5 are hydrogen, R.sup.2 and R.sup.3 are alkyl groups having 1-4 carbon atoms or hydroxymethyl groups;R.sup.4 and R.sup.5 are hydrogen but where both R.sup.2 and R.sup.3 are hydrogen, R.sup.4 but R.sup.5 stand for alkyl groups having 1-4 carbon atoms, are amino groups, which may be mono or di-substituted by alkyl groups having 1-4 carbon atoms, or are allyloxymethyl groups;X is an oxygen or sulphur atom or an NH group;Y stands for a halogen atom or a halogeno-substituted phenyl group. The disclosure also concerns a process for the preparation of such compounds.