Abstract: A system for determining microbiome from host metabolome using a machine learning model is provided. The system 100 includes a sample collection device 102, an analytical device 104, a network 106, and a microbiome profile determination server 108 that includes a machine learning model 110. The sample collection device 102 collects sample (e.g. blood) from the host. The analytical device 104 analyzes the sample to obtain mass spectral data of one or more metabolites present in the sample. The microbiome profile determination server 108 is configured to (i) receive the mass spectral data from the analytical device 104 through the network 106, (ii) identify metabolome data associated with the sample by analysing and annotating the mass spectral data of the sample against known metabolites in public database, and (iii) determine the microbiome profile of the host based on the metabolome data using the machine learning model 110.

Abstract: The invention relates to polymers comprising metal-containing nucleic acid duplexes. Methods of using the metal-containing nucleic acid duplexes to provoke physiological responses in a host animal are provided, such as immunological methods that produce antibodies in the host.

Abstract: The invention relates to polymers comprising metal-containing nucleic acid duplexes. Methods of using the metal-containing nucleic acid duplexes to provoke physiological responses in a host animal are provided, such as immunological methods that produce antibodies in the host.

Abstract: The invention relates to polymers comprising metal-containing nucleic acid duplexes. Methods of using the metal-containing nucleic acid duplexes to provoke physiological responses in a host animal are provided, such as immunological methods that produce antibodies in the host.

Abstract: The invention provides conductive polymers comprising metal-containing nucleic acid duplexes electrically coupled to an electron source. Methods for making conductive metal-containing nucleic acid duplexes are provided, comprising subjecting a nucleic acid duplex to basic conditions in the presence of a divalent metal cation. Methods of using conductive metal-containing nucleic acid duplexes are provided, including methods of genomic analysis, methods of molecular screening and immunological methods that produce antibodies to such molecules.