Abstract: Described herein are methods for delivering live cells into tissue, such as skin or other animal tissue, that has been treated with a laser (e.g. at a minimally coagulating setting) to produce voids/channels/grooves in the tissue. It has been surprisingly discovered that voids having a minimal coagulation zone around the ablation void provide a receptive environment into which live cells are readily delivered (without the need for injections into the target tissue) and can therefore survive and persist.

Abstract: Photocosmetic device for use in medical or non-medical environments (e.g., a home, barbershop, or spa), which can be used for a variety of tissue treatments. Radiation is delivered to the tissue via optical systems designed to pattern the radiation and project the radiation to a particular depth. The device has a variety of cooling systems including phase change cooling solids and liquids to cool treated skin and the radiation sources. Contact sensors and motion sensor may be used to enhance treatment. The device may be modular to facilitate manufacture and replacement of parts.