Abstract: A method for fabricating a flexible, blood pumping membrane for use within an artificial ventricle, involves the steps of selecting a mold configured to provide a dome shaped diaphragm biased in a static mode to a systolic configuration and suitable for use within a ventricular housing as a part of a blood pumping membrane. The specific steps include forming the dome shaped diaphragm on a surface of the mold to include (i) a perimeter comprising at least a portion of a diaphragm/housing interface which is configured to connect the dome shaped diaphragm with the ventricular housing to enclose a blood pumping chamber, and (ii) an intermediate annular section of the dome shaped diaphragm extending inward from the diaphragm/housing interface in a configuration corresponding to that portion of the diaphragm when the ventricle is substantially at full systole.