Abstract: The present disclosure is related to a polymorphic form of ritonavir prepared by novel methods that require less time to produce the polymorphic form, the methods of preparing the polymorphic form, pharmaceutical compositions comprising the polymorphic form produced by the provided methods, and corresponding methods of treatment with the polymorphic form produced by the provided methods.

Abstract: Compositions comprising, for example, caffeine, sodium benzoate and one or more of lactic acid, acetic acid, aspartic acid and glutamic acid, processes for making the compositions and methods of using the compositions. The methods include accelerating emergence from anesthesia and/or countering the effects of anesthesia, including reversing the effects of anesthesia. The methods also include treating opioid intoxication or overdose.

Abstract: The present disclosure is directed to compositions of caffeine citrate. In addition, the present disclosure includes processes of making compositions of caffeine citrate and methods of treatment using caffeine citrate. Such methods include methods of accelerating emergence from anesthesia by delivering compositions of caffeine citrate of the disclosure.