Patents by Inventor Pamela Contag

Pamela Contag has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Apparatus and methods for fluorescence guided surgery
    Patent number: 9080977
    Abstract: Disclosed are apparatus and methods for quantifying fluorescent distribution within a surgery site of a patient in an operating room, wherein the surgery site has been exposed for a surgery procedure. Excitation light is provided at each of a plurality of positions at the surgery site in a method embodiment. The excitation light is significantly more intense than any other light sources that are present in the operating room. Fluorescent emission is detected from the surgery site in response to each of the excitation light positions so as to obtain a fluorescent emission image for each excitation light position. The fluorescent light distribution that is internal to a surface of the surgery site is quantified based on the obtained fluorescent emission images.
    Type: Grant
    Filed: October 23, 2007
    Date of Patent: July 14, 2015
    Assignee: Xenogen Corporation
    Inventors: Pamela Contag, Bradley W. Rice
  • Isolation and identification of mouse and human transcription control elements associated with cytochrome expression
    Patent number: 7449567
    Abstract: The present invention relates to transcription control elements derived from mouse and human genes associated with cytochrome expression, e.g., Cyp3A11 and CYP3A4, respectively. Isolated polynucleotides, expression cassettes, vectors, recombinant cells, and transgenic animals, may comprise such transcription control elements as described herein.
    Type: Grant
    Filed: April 11, 2002
    Date of Patent: November 11, 2008
    Assignee: Xenogen Corporation
    Inventors: Weisheng Zhang, Pamela Contag, Anthony Purchio, Sandy Hashima, Shirley Ma, Kevin Nawotka
  • APPARATUS AND METHODS FOR FLUORESCENCE GUIDED SURGERY
    Publication number: 20080103390
    Abstract: Disclosed are apparatus and methods for quantifying fluorescent distribution within a surgery site of a patient in an operating room, wherein the surgery site has been exposed for a surgery procedure. Excitation light is provided at each of a plurality of positions at the surgery site in a method embodiment. The excitation light is significantly more intense than any other light sources that are present in the operating room. Fluorescent emission is detected from the surgery site in response to each of the excitation light positions so as to obtain a fluorescent emission image for each excitation light position. The fluorescent light distribution that is internal to a surface of the surgery site is quantified based on the obtained fluorescent emission images.
    Type: Application
    Filed: October 23, 2007
    Publication date: May 1, 2008
    Applicant: XENOGEN CORPORATION
    Inventors: Pamela Contag, Bradley Rice
  • Isolation and identification of transcription control elements associated with mouse eosinophil peroxidase expression
    Patent number: 7115793
    Abstract: The present invention relates to novel transcription control elements derived from a mouse eosinophil peroxidase gene. Such transcription control elements may comprise isolated polynucleotides, expression cassettes, vectors, recombinant cells, and transgenic animals, as described herein.
    Type: Grant
    Filed: November 16, 2004
    Date of Patent: October 3, 2006
    Assignee: Xenogen Corporation
    Inventors: Hongbing Zhang, Pamela Contag, Anthony Purchio, Amy Holt
  • Non-invasive localization of a light-emitting conjugate in a mammal
    Publication number: 20050287072
    Abstract: Methods and compositions for detecting and localizing light originating from a mammal are disclosed. Also disclosed are methods for targeting light emission to selected regions, as well as for tracking entities within the mammal. In addition, animal models for disease states are disclosed, as are methods for localizing and tracking the progression of disease or a pathogen within the animal, and for screening putative therapeutic compounds effective to inhibit the disease or pathogen.
    Type: Application
    Filed: June 2, 2005
    Publication date: December 29, 2005
    Inventors: Pamela Contag, Christopher Contag, David Benaron
  • Non-invasive localization of a light-emitting conjugate in a mammal
    Publication number: 20050238582
    Abstract: Methods and compositions for detecting and localizing light originating from a mammal are disclosed. Also disclosed are methods for targeting light emission to selected regions, as well as for tracking entities within the mammal. In addition, animal models for disease states are disclosed, as are methods for localizing and tracking the progression of disease or a pathogen within the animal, and for screening putative therapeutic compounds effective to inhibit the disease or pathogen.
    Type: Application
    Filed: June 8, 2005
    Publication date: October 27, 2005
    Inventors: Pamela Contag, Christopher Contag, David Benaron
  • Isolation and identification of transcription control elements associated with mouse eosinophil peroxidase expression
    Publication number: 20050138678
    Abstract: The present invention relates to novel transcription control elements derived from a mouse eosinophil peroxidase gene. Such transcription control elements may comprise isolated polynucleotides, expression cassettes, vectors, recombinant cells, and transgenic animals, as described herein.
    Type: Application
    Filed: November 16, 2004
    Publication date: June 23, 2005
    Inventors: Hongbing Zhang, Pamela Contag, Anthony Purchio, Amy Holt
  • Transgenic mice comprising transcription control elements associated with mouse eosinophil peroxidase expression
    Patent number: 6858773
    Abstract: The present invention relates to novel transcription control elements derived from a mouse eosinophil peroxidase gene. The novel transcription control elements described in the disclosure may comprise isolated polynucleotides, expression cassettes, vectors, recombinant cells, and transgenic animals.
    Type: Grant
    Filed: April 19, 2002
    Date of Patent: February 22, 2005
    Assignee: Xenogen Corporation
    Inventors: Hongbing Zhang, Pamela Contag, Anthony Purchio, Amy Holt
  • Isolation and identification of mouse and human transcription control elements associated with cytochrome expression
    Publication number: 20030145341
    Abstract: The present invention relates to transcription control elements derived from mouse and human genes associated with cytochrome expression, e.g., Cyp3A11 and CYP3A4, respectively. Isolated polynucleotides, expression cassettes, vectors, recombinant cells, and transgenic animals, may comprise such transcription control elements as described herein.
    Type: Application
    Filed: April 11, 2002
    Publication date: July 31, 2003
    Inventors: Weisheng Zhang, Pamela Contag, Anthony Purchio, Sandy Hashima, Shirley Ma, Kevin Nawotka
  • Isolation and identification of transcription control elements associated with mouse eosinophil peroxidase expression
    Publication number: 20030005472
    Abstract: The present invention relates to novel transcription control elements derived from a mouse eosinophil peroxidase gene. Such transcription control elements may comprise isolated polynucleotides, expression cassettes, vectors, recombinant cells, and transgenic animals, as described herein.
    Type: Application
    Filed: April 19, 2002
    Publication date: January 2, 2003
    Inventors: Hongbing Zhang, Pamela Contag, Anthony Purchio, Amy Holt