Patents by Inventor Pamela Jean Mitchell

Pamela Jean Mitchell has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Anti-myostatin antibodies
    Patent number: 8066995
    Abstract: Anti-myostatin antibodies are identified that are characterized as having high affinity and may be chimeric, humanized or fully human antibodies, immunoconjugates of the antibodies or antigen-binding fragments thereof. The antibodies of the invention are useful for increasing muscle mass, increasing bond density, or for the treatment of various disorders in mammalian and avian species, X17251.
    Type: Grant
    Filed: November 3, 2009
    Date of Patent: November 29, 2011
    Assignee: Eli Lilly and Company
    Inventors: Julian Davies, Bryan Edward Jones, Andrew Ihor Korytko, Pamela Jean Mitchell, Rosamund Carol Smith, Linda O'Bryan (Nee Tobias), Rong Wang
  • Anti-myostatin antibodies
    Patent number: 7745583
    Abstract: A neutralizing epitope is identified within amino acids 40-64 of the mature form of human myostatin. Antibodies that bind this epitope with high affinity preferentially bind GDF-8 over GDF-11 and may be chimeric, humanized or fully human antibodies, immunoconjugates of the antibodies or antigen-binding fragments thereof. The antibodies of the invention are useful for increasing muscle mass, increasing hone density, or for the treatment of various disorders in mammalian and avian species.
    Type: Grant
    Filed: November 4, 2009
    Date of Patent: June 29, 2010
    Assignee: Eli Lilly and Company
    Inventors: Bomie Han, Andrew Ihor Korytko, Pamela Jean Mitchell, Rosamund Carol Smith, Linda O'Bryan (Nee Tobias), Rong Wang
  • ANTI-MYOSTATIN ANTIBODIES
    Publication number: 20100087631
    Abstract: A neutralizing epitope is identified within amino acids 40-64 of the mature form of human myostatin. Antibodies that bind this epitope with high affinity preferentially bind GDF-8 over GDF-11 and may he chimeric, humanized or fully human antibodies, immunoconjugates of the antibodies or antigen-binding fragments thereof. The antibodies of the invention are useful for increasing muscle mass, increasing hone density, or for the treatment of various disorders in mammalian and avian species.
    Type: Application
    Filed: November 4, 2009
    Publication date: April 8, 2010
    Applicant: ELI LILLY AND COMPANY
    Inventors: BOMIE HAN, ANDREW KORYTKO, PAMELA JEAN MITCHELL, LINDA O'BRYAN (NEE TOBIAS), RONG WANG, ROSAMUND CAROL SMITH
  • ANTI-MYOSTATIN ANTIBODIES
    Publication number: 20100080811
    Abstract: Anti-myostatin antibodies are identified that are characterized as having high affinity and may be chimeric, humanized or fully human antibodies, immunoconjugates of the antibodies or antigen-binding fragments thereof. The antibodies of the invention are useful for increasing muscle mass, increasing bone density, or for the treatment of various disorders in mammalian and avian species.
    Type: Application
    Filed: November 3, 2009
    Publication date: April 1, 2010
    Inventors: JULIAN DAVIES, BRYAN EDWARD JONES, ANDREW IHOR KORYTKO, PAMELA JEAN MITCHELL, ROSAMUND CAROL SMITH, LINDA MAUREEN O'BRYAN (NEE TOBIAS), RONG WANG
  • Anti-myostatin antibodies
    Patent number: 7635760
    Abstract: A neutralizing epitope is identified within amino acids 40-64 of the mature form of human myostatin. Antibodies that bind this epitope with high affinity preferentially bind GDF-8 over GDF-11 and may be chimeric, humanized or fully human antibodies, immunoconjugates of the antibodies or antigen-binding fragments thereof. The antibodies of the invention are useful for increasing muscle mass, increasing bone density, or for the treatment of various disorders in mammalian and avian species.
    Type: Grant
    Filed: October 5, 2006
    Date of Patent: December 22, 2009
    Assignee: Eli Lilly and Company
    Inventors: Bomie Han, Andrew Korytko, Pamela Jean Mitchell, Linda O'Bryan, Rong Wang, Rosamund Carol Smith
  • Anti-myostatin antibodies
    Patent number: 7632499
    Abstract: Anti-myostatin antibodies are identified that are characterized as having high affinity and may be chimeric, humanized or fully human antibodies, immunoconjugates of the antibodies or antigen-binding fragments thereof. The antibodies of the invention are useful for increasing muscle mass, increasing bone density, or for the treatment of various disorders in mammalian and avian species.
    Type: Grant
    Filed: October 5, 2006
    Date of Patent: December 15, 2009
    Assignee: Eli Lilly and Company
    Inventors: Julian Davies, Bryan Edward Jones, Andrew Ihor Korytko, Pamela Jean Mitchell, Rosamund Carol Smith, Linda Maureen O'Bryan, Rong Wang
  • ANTI-MYOSTATIN ANTIBODIES
    Publication number: 20090131638
    Abstract: Anti-myostatin antibodies are identified that are characterized as having high affinity and may be chimeric, humanized or fully human antibodies, immunoconjugates of the antibodies or antigen-binding fragments thereof. The antibodies of the invention are useful for increasing muscle mass, increasing bone density, or for the treatment of various disorders in mammalian and avian species.
    Type: Application
    Filed: October 5, 2006
    Publication date: May 21, 2009
    Inventors: Julian Davies, Bryan Edward Jones, Andrew Ihor Korytko, Pamela Jean Mitchell, Rosamund Carol Smith, Linda Maureen O'Bryan (nee Tobias), Rong Wang
  • Anti-Myostatin Antibodies
    Publication number: 20080299126
    Abstract: A neutralizing epitope is identified within amino acids 40-64 of the mature form of human myostatin. Antibodies that bind this epitope with high affinity preferentially bind GDF-8 over GDF-11 and may be chimeric, humanized or fully human antibodies, immunoconjugates of the antibodies or antigen-binding fragments thereof. The antibodies of the invention are useful for increasing muscle mass, increasing bone density, or for the treatment of various disorders in mammalian and avian species.
    Type: Application
    Filed: October 5, 2006
    Publication date: December 4, 2008
    Inventors: Bomie Han, Andrew Korytko, Pamela Jean Mitchell, Linda O'Bryan (nee Tobias), Rong Wang, Rosamund Carol Smith